CA3115383A1 - Modified t lymphocytes having improved specificity - Google Patents
Modified t lymphocytes having improved specificityInfo
- Publication number
- CA3115383A1 CA3115383A1 CA3115383A CA3115383A CA3115383A1 CA 3115383 A1 CA3115383 A1 CA 3115383A1 CA 3115383 A CA3115383 A CA 3115383A CA 3115383 A CA3115383 A CA 3115383A CA 3115383 A1 CA3115383 A1 CA 3115383A1
- Authority
- CA
- Canada
- Prior art keywords
- antigen
- modified
- lymphocyte
- polypeptide
- domain
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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Classifications
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| US11071754B2 (en) | 2013-03-11 | 2021-07-27 | Case Western Reserve University | Method of generating tumor-specific T cells |
| US9944898B2 (en) * | 2013-03-11 | 2018-04-17 | Case Western Reserve University | Method of generating tumor-specific T cells |
| CN105518018B (zh) | 2013-03-15 | 2020-04-03 | 细胞基因公司 | 修饰的t淋巴细胞 |
| CN105246504A (zh) | 2013-03-15 | 2016-01-13 | 纪念斯隆-凯特琳癌症中心 | 用于免疫疗法的组合物和方法 |
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| CN107109420A (zh) | 2014-07-21 | 2017-08-29 | 诺华股份有限公司 | 使用cll－1嵌合抗原受体的癌症治疗 |
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| KR20180029201A (ko) | 2015-05-18 | 2018-03-20 | 티씨알2 테라퓨틱스 인크. | 융합 단백질을 이용하는 tcr 리프로그래밍을 위한 조성물 및 방법 |
| US11655452B2 (en) * | 2015-06-25 | 2023-05-23 | Icell Gene Therapeutics Inc. | Chimeric antigen receptors (CARs), compositions and methods of use thereof |
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| JP7054924B2 (ja) | 2015-09-23 | 2022-04-15 | サイトイミューン セラピューティクス， インコーポレイテッド | 免疫療法のためのｆｌｔ３指向ｃａｒ細胞 |
| WO2017069958A2 (en) | 2015-10-09 | 2017-04-27 | The Brigham And Women's Hospital, Inc. | Modulation of novel immune checkpoint targets |
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