CA3091313A1 - Pharmaceutical composition comprising timolol - Google Patents

Pharmaceutical composition comprising timolol Download PDF

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Publication number
CA3091313A1
CA3091313A1 CA3091313A CA3091313A CA3091313A1 CA 3091313 A1 CA3091313 A1 CA 3091313A1 CA 3091313 A CA3091313 A CA 3091313A CA 3091313 A CA3091313 A CA 3091313A CA 3091313 A1 CA3091313 A1 CA 3091313A1
Authority
CA
Canada
Prior art keywords
pharmaceutical composition
timolol
present
eye
semifluorinated alkane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3091313A
Other languages
English (en)
French (fr)
Inventor
Frank Loscher
Sonja Krosser
Diana Strehl
Bernhard Hauptmeier
Kirsten EICKHOFF
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novaliq GmbH
Original Assignee
Novaliq GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novaliq GmbH filed Critical Novaliq GmbH
Publication of CA3091313A1 publication Critical patent/CA3091313A1/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA3091313A 2018-03-28 2019-03-25 Pharmaceutical composition comprising timolol Pending CA3091313A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP18164563 2018-03-28
EP18164563.1 2018-03-28
EP18185436 2018-07-25
EP18185436.5 2018-07-25
PCT/EP2019/057429 WO2019185543A1 (en) 2018-03-28 2019-03-25 Pharmaceutical composition comprising timolol

Publications (1)

Publication Number Publication Date
CA3091313A1 true CA3091313A1 (en) 2019-10-03

Family

ID=65818028

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3091313A Pending CA3091313A1 (en) 2018-03-28 2019-03-25 Pharmaceutical composition comprising timolol

Country Status (12)

Country Link
US (2) US20210121471A1 (enExample)
EP (1) EP3773469A1 (enExample)
JP (1) JP7496778B2 (enExample)
KR (1) KR102882058B1 (enExample)
CN (1) CN111867560B (enExample)
AU (1) AU2019246035B2 (enExample)
BR (1) BR112020017841A2 (enExample)
CA (1) CA3091313A1 (enExample)
IL (1) IL276888B2 (enExample)
MX (1) MX2020010078A (enExample)
SG (1) SG11202007860XA (enExample)
WO (1) WO2019185543A1 (enExample)

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CN111182893A (zh) 2017-10-04 2020-05-19 诺瓦利克有限责任公司 包含f6h8的眼用组合物
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CN111867560A (zh) 2020-10-30
WO2019185543A1 (en) 2019-10-03
SG11202007860XA (en) 2020-09-29
BR112020017841A2 (pt) 2020-12-22
JP2021518352A (ja) 2021-08-02
IL276888B1 (en) 2024-08-01
US20210121471A1 (en) 2021-04-29
AU2019246035B2 (en) 2024-07-18
KR102882058B1 (ko) 2025-11-07
AU2019246035A1 (en) 2020-09-10
EP3773469A1 (en) 2021-02-17
US12599607B2 (en) 2026-04-14
MX2020010078A (es) 2021-02-26
JP7496778B2 (ja) 2024-06-07
IL276888A (en) 2020-10-29
US20240366621A1 (en) 2024-11-07
KR20200136403A (ko) 2020-12-07
CN111867560B (zh) 2024-08-13

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