CA3069047A1 - A universal vaccine based on shared tumor neoantigens for prevention and treatment of micro satellite instable (msi) cancers - Google Patents
A universal vaccine based on shared tumor neoantigens for prevention and treatment of micro satellite instable (msi) cancers Download PDFInfo
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- CA3069047A1 CA3069047A1 CA3069047A CA3069047A CA3069047A1 CA 3069047 A1 CA3069047 A1 CA 3069047A1 CA 3069047 A CA3069047 A CA 3069047A CA 3069047 A CA3069047 A CA 3069047A CA 3069047 A1 CA3069047 A1 CA 3069047A1
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- A61K2039/515—Animal cells
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Landscapes
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- Wood Science & Technology (AREA)
- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
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| EP17181026 | 2017-07-12 | ||
| EP17181026.0 | 2017-07-12 | ||
| PCT/EP2018/069032 WO2019012082A1 (en) | 2017-07-12 | 2018-07-12 | UNIVERSAL VACCINE BASED ON SHARED TUMOR NEO-ANTIGENS FOR THE PREVENTION AND TREATMENT OF MICRO-SATELLITE INSTABILITY CANCER (MSI) |
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| CA3069047A1 true CA3069047A1 (en) | 2019-01-17 |
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| CA3069047A Pending CA3069047A1 (en) | 2017-07-12 | 2018-07-12 | A universal vaccine based on shared tumor neoantigens for prevention and treatment of micro satellite instable (msi) cancers |
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| WO2020022897A1 (en) | 2018-07-26 | 2020-01-30 | Frame Pharmaceuticals B.V. | Method of preparing subject-specific immunogenic compositions based on a neo open-reading-frame peptide database |
| EP3827265A1 (en) | 2018-07-26 | 2021-06-02 | Frame Pharmaceuticals B.V. | Cancer vaccines for kidney cancer |
| IL321692A (en) | 2018-07-26 | 2025-08-01 | Curevac Netherlands B V | Cancer vaccines for colorectal cancer |
| US20210162032A1 (en) | 2018-07-26 | 2021-06-03 | Frame Pharmaceuticals B.V. | Cancer vaccines for breast cancer |
| WO2020022901A1 (en) | 2018-07-26 | 2020-01-30 | Frame Pharmaceuticals B.V. | Cancer vaccines for uterine cancer |
| US20210252123A1 (en) | 2018-07-26 | 2021-08-19 | Frame Pharmaceuticals B.V. | ARID1A, CDKN2A, KMT2B, KMT2D, TP53 and PTEN VACCINES FOR CANCER |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| WO2020163802A1 (en) * | 2019-02-07 | 2020-08-13 | Arizona Board Of Regents On Behalf Of Arizona State University | Cancer specific frameshift vaccines |
| CA3161800A1 (en) | 2019-11-18 | 2021-05-27 | Janssen Biotech, Inc. | Vaccines based on mutant calr and jak2 and their uses |
| US20230212243A1 (en) * | 2020-05-12 | 2023-07-06 | Institut Curie | Neoantigenic Epitopes Associated with SF3B1 Mutations |
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| US20060160090A1 (en) * | 2003-04-11 | 2006-07-20 | Macina Robert A | Composition splice variants and methods relating to cancer specific genes and proteins |
| CN1824325A (zh) * | 2005-12-16 | 2006-08-30 | 武汉大学 | 人乳头病毒dna嵌合疫苗及制备方法和应用 |
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2018
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| CN111328420A (zh) | 2020-06-23 |
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| HUE061840T2 (hu) | 2023-08-28 |
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| ES2940087T3 (es) | 2023-05-03 |
| RU2019144505A (ru) | 2021-08-12 |
| BR112020000590A2 (pt) | 2020-07-14 |
| IL271966B1 (en) | 2024-09-01 |
| JP2020532288A (ja) | 2020-11-12 |
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| PL3652606T3 (pl) | 2023-04-24 |
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| IL271966B2 (en) | 2025-01-01 |
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| AU2018298849B2 (en) | 2022-07-14 |
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