ES2940087T3 - Una vacuna universal basada en neoantígenos tumorales compartidos para la prevención y el tratamiento de cánceres con inestabilidad microsatelital (MSI) - Google Patents
Una vacuna universal basada en neoantígenos tumorales compartidos para la prevención y el tratamiento de cánceres con inestabilidad microsatelital (MSI) Download PDFInfo
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- ES2940087T3 ES2940087T3 ES18742985T ES18742985T ES2940087T3 ES 2940087 T3 ES2940087 T3 ES 2940087T3 ES 18742985 T ES18742985 T ES 18742985T ES 18742985 T ES18742985 T ES 18742985T ES 2940087 T3 ES2940087 T3 ES 2940087T3
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
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- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
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Landscapes
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- Plant Pathology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
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| EP17181026 | 2017-07-12 | ||
| PCT/EP2018/069032 WO2019012082A1 (en) | 2017-07-12 | 2018-07-12 | UNIVERSAL VACCINE BASED ON SHARED TUMOR NEO-ANTIGENS FOR THE PREVENTION AND TREATMENT OF MICRO-SATELLITE INSTABILITY CANCER (MSI) |
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| ES2940087T3 true ES2940087T3 (es) | 2023-05-03 |
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| US20220349010A1 (en) | 2018-07-26 | 2022-11-03 | Frame Pharmaceuticals B.V. | Method of preparing subject-specific immunogenic compositions based on a neo open-reading-frame peptide database |
| IL280112B2 (en) | 2018-07-26 | 2025-11-01 | Curevac Netherlands B V | Cancer vaccines for breast cancer |
| CA3106567A1 (en) | 2018-07-26 | 2020-01-30 | Frame Pharmaceuticals B.V. | Cancer vaccines for kidney cancer |
| IL280113B2 (en) | 2018-07-26 | 2025-11-01 | Curevac Netherlands B V | Cancer vaccines for uterine cancer |
| US12005104B2 (en) | 2018-07-26 | 2024-06-11 | Curevac Netherlands B.V. | Cancer vaccines for colorectal cancer |
| WO2020022903A1 (en) | 2018-07-26 | 2020-01-30 | Frame Pharmaceuticals B.V. | ARID1A, CDKN2A, KMT2B, KMT2D, TP53 and PTEN VACCINES FOR CANCER |
| TWI852977B (zh) | 2019-01-10 | 2024-08-21 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
| US20220008525A1 (en) * | 2019-02-07 | 2022-01-13 | Arizona Board Of Regents On Behalf Of Arizona State University | Cancer specific frameshift vaccines |
| CN114980920A (zh) | 2019-11-18 | 2022-08-30 | 詹森生物科技公司 | 基于突变体calr和jak2的疫苗及其用途 |
| US20230212243A1 (en) * | 2020-05-12 | 2023-07-06 | Institut Curie | Neoantigenic Epitopes Associated with SF3B1 Mutations |
| WO2022009052A2 (en) | 2020-07-06 | 2022-01-13 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
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| AU2003232485A1 (en) * | 2002-04-18 | 2003-10-27 | Mtm Laboratories Ag | Neopeptides and methods useful for detection and treatment of cancer |
| WO2004092338A2 (en) * | 2003-04-11 | 2004-10-28 | Diadexus, Inc. | Compositions, splice variants and methods relating to cancer specific genes and proteins |
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2018
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| EP3652606B1 (en) | 2023-01-11 |
| HUE061840T2 (hu) | 2023-08-28 |
| PL3652606T3 (pl) | 2023-04-24 |
| KR20200029443A (ko) | 2020-03-18 |
| CN111328420B (zh) | 2023-07-25 |
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| CN111328420A (zh) | 2020-06-23 |
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| AU2018298849B2 (en) | 2022-07-14 |
| CA3069047A1 (en) | 2019-01-17 |
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| PT3652606T (pt) | 2023-03-16 |
| NZ759940A (en) | 2023-07-28 |
| IL271966A (en) | 2020-02-27 |
| AU2018298849A1 (en) | 2020-01-02 |
| JP7274223B2 (ja) | 2023-05-16 |
| SG11202000250PA (en) | 2020-02-27 |
| EP3652606A1 (en) | 2020-05-20 |
| JP2020532288A (ja) | 2020-11-12 |
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| MX2020000413A (es) | 2020-09-28 |
| BR112020000590A2 (pt) | 2020-07-14 |
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| US11578109B2 (en) | 2023-02-14 |
| WO2019012082A9 (en) | 2019-05-02 |
| KR102709778B1 (ko) | 2024-09-26 |
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