CA3063715A1 - Combination therapies for treating cancer - Google Patents

Combination therapies for treating cancer Download PDF

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Publication number
CA3063715A1
CA3063715A1 CA3063715A CA3063715A CA3063715A1 CA 3063715 A1 CA3063715 A1 CA 3063715A1 CA 3063715 A CA3063715 A CA 3063715A CA 3063715 A CA3063715 A CA 3063715A CA 3063715 A1 CA3063715 A1 CA 3063715A1
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CA
Canada
Prior art keywords
agent
cancer
macrophage
group
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3063715A
Other languages
English (en)
French (fr)
Inventor
Kaiming Sun
Jing Yu WANG
Zebin Wang
Original Assignee
Tesaro Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tesaro Inc filed Critical Tesaro Inc
Publication of CA3063715A1 publication Critical patent/CA3063715A1/en
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA3063715A 2017-05-18 2018-05-18 Combination therapies for treating cancer Pending CA3063715A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201762508363P 2017-05-18 2017-05-18
US62/508,363 2017-05-18
US201762508481P 2017-05-19 2017-05-19
US62/508,481 2017-05-19
US201762578204P 2017-10-27 2017-10-27
US62/578,204 2017-10-27
PCT/US2018/033437 WO2018213732A1 (en) 2017-05-18 2018-05-18 Combination therapies for treating cancer

Publications (1)

Publication Number Publication Date
CA3063715A1 true CA3063715A1 (en) 2018-11-22

Family

ID=62705671

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3063715A Pending CA3063715A1 (en) 2017-05-18 2018-05-18 Combination therapies for treating cancer

Country Status (12)

Country Link
US (1) US11622961B2 (enExample)
EP (1) EP3624850A1 (enExample)
JP (1) JP2020520921A (enExample)
KR (1) KR20200005662A (enExample)
CN (1) CN110913911A (enExample)
AU (2) AU2018270112A1 (enExample)
BR (1) BR112019024135A2 (enExample)
CA (1) CA3063715A1 (enExample)
IL (1) IL270720A (enExample)
MA (1) MA49144A (enExample)
MX (1) MX2019013755A (enExample)
WO (1) WO2018213732A1 (enExample)

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US20190233533A1 (en) 2016-06-28 2019-08-01 Umc Utrecht Holding B.V. Treatment Of IgE-Mediated Diseases With Antibodies That Specifically Bind CD38
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AU2019336345A1 (en) * 2018-09-04 2021-04-15 Pfizer Inc. CD47 blockade with parp inhibition for disease treatment
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TWI877433B (zh) * 2020-11-30 2025-03-21 大陸商杭州阿諾生物醫藥科技有限公司 用於治療ｐｉｋ３ｃａ突變癌症的組合療法
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CN116726187B (zh) * 2023-07-26 2025-09-30 珠海市人民医院 一种小分子配体-鲁卡帕尼偶联物及其制备方法
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116370607A (zh) * 2023-03-20 2023-07-04 中国人民解放军陆军军医大学第一附属医院 人重组hmgb1在制备治疗胶质瘤化疗增敏剂中的应用

Also Published As

Publication number Publication date
US11622961B2 (en) 2023-04-11
MA49144A (fr) 2020-03-25
IL270720A (en) 2020-01-30
US20210008053A1 (en) 2021-01-14
EP3624850A1 (en) 2020-03-25
BR112019024135A2 (pt) 2020-06-02
MX2019013755A (es) 2020-07-20
CN110913911A (zh) 2020-03-24
JP2020520921A (ja) 2020-07-16
AU2021215113A1 (en) 2021-08-26
KR20200005662A (ko) 2020-01-15
AU2018270112A1 (en) 2019-12-12
WO2018213732A1 (en) 2018-11-22

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