CA3050042A1 - Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid - Google Patents

Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid Download PDF

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Publication number
CA3050042A1
CA3050042A1 CA3050042A CA3050042A CA3050042A1 CA 3050042 A1 CA3050042 A1 CA 3050042A1 CA 3050042 A CA3050042 A CA 3050042A CA 3050042 A CA3050042 A CA 3050042A CA 3050042 A1 CA3050042 A1 CA 3050042A1
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CA
Canada
Prior art keywords
gene
acid
microorganism
glycolic acid
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3050042A
Other languages
English (en)
French (fr)
Inventor
Wanda Dischert
Gwenaelle Corre
Philippe Soucaille
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Metabolic Explorer SA
Original Assignee
Metabolic Explorer SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolic Explorer SA filed Critical Metabolic Explorer SA
Publication of CA3050042A1 publication Critical patent/CA3050042A1/en
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/03—Oxidoreductases acting on the CH-OH group of donors (1.1) with a oxygen as acceptor (1.1.3)
    • C12Y101/03015—(S)-2-Hydroxy-acid oxidase (1.1.3.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/02—Aldehyde-lyases (4.1.2)
    • C12Y401/02009—Phosphoketolase (4.1.2.9)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/02—Aldehyde-lyases (4.1.2)
    • C12Y401/02022—Fructose-6-phosphate phosphoketolase (4.1.2.22)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA3050042A 2017-01-26 2018-01-26 Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid Pending CA3050042A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17305084.0 2017-01-26
EP17305084.0A EP3354742A1 (en) 2017-01-26 2017-01-26 Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid
PCT/EP2018/051919 WO2018138240A1 (en) 2017-01-26 2018-01-26 Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid

Publications (1)

Publication Number Publication Date
CA3050042A1 true CA3050042A1 (en) 2018-08-02

Family

ID=58016654

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3050042A Pending CA3050042A1 (en) 2017-01-26 2018-01-26 Methods and microorganisms for the production of glycolic acid and/or glyoxylic acid

Country Status (8)

Country Link
US (1) US10774320B2 (cg-RX-API-DMAC7.html)
EP (2) EP3354742A1 (cg-RX-API-DMAC7.html)
JP (2) JP7043504B2 (cg-RX-API-DMAC7.html)
KR (1) KR102324663B1 (cg-RX-API-DMAC7.html)
CN (1) CN110234768B (cg-RX-API-DMAC7.html)
BR (1) BR112019015309A2 (cg-RX-API-DMAC7.html)
CA (1) CA3050042A1 (cg-RX-API-DMAC7.html)
WO (1) WO2018138240A1 (cg-RX-API-DMAC7.html)

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US11414664B2 (en) * 2008-12-18 2022-08-16 Dicerna Pharmaceuticals, Inc. Extended dicer substrate agents and methods for the specific inhibition of gene expression
BR112021015719A2 (pt) * 2019-02-20 2021-12-14 Braskem Sa Micro-organismos e métodos para produção de compostos oxigenados a partir de hexoses
CN110760561A (zh) * 2019-10-31 2020-02-07 申友基因组研究院(南京)有限公司 一种酶法检测甘氨酸含量的方法及其应用
EP4631928A1 (en) 2024-04-10 2025-10-15 Metabolic Explorer Method of purification of glycolic acid, composition and use thereof
CN118638831B (zh) * 2024-08-13 2024-10-29 中国农业科学院北京畜牧兽医研究所 具有噬菌体抗性生产甲基苹果酸的大肠杆菌工程菌株、构建及发酵生产方法

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TW294723B (cg-RX-API-DMAC7.html) 1991-09-06 1997-01-01 Du Pont
ATE139796T1 (de) 1992-01-06 1996-07-15 Du Pont Oxydation von glykolsäure zur herstellung von glyoxylsäure unter verwendung von transformierten mikrobiellen zellen als katalysator.
HUT73214A (en) 1993-03-03 1996-06-28 Du Pont Production of glycolate oxidase in methylotrophic yeast
JPH10501984A (ja) 1993-03-03 1998-02-24 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 形質転換微生物を用いて製造されるグリオキシル酸／アミノメチルホスホン酸混合物
CN1124981A (zh) 1993-05-28 1996-06-19 纳幕尔杜邦公司 水合乙醛酸/氨甲基膦酸二烷基酯混合物的制备方法
WO1995001444A1 (en) 1993-07-01 1995-01-12 E.I. Du Pont De Nemours And Company Glycolate oxidase production
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Also Published As

Publication number Publication date
JP7043504B2 (ja) 2022-03-29
KR20190103441A (ko) 2019-09-04
US20190367898A1 (en) 2019-12-05
KR102324663B1 (ko) 2021-11-10
JP2022046736A (ja) 2022-03-23
BR112019015309A2 (pt) 2020-05-19
US10774320B2 (en) 2020-09-15
CN110234768A (zh) 2019-09-13
EP3574106A1 (en) 2019-12-04
EP3354742A1 (en) 2018-08-01
WO2018138240A1 (en) 2018-08-02
CN110234768B (zh) 2023-09-01
JP2020505922A (ja) 2020-02-27

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