BR112021015719A2 - Micro-organismos e métodos para produção de compostos oxigenados a partir de hexoses - Google Patents

Micro-organismos e métodos para produção de compostos oxigenados a partir de hexoses

Info

Publication number
BR112021015719A2
BR112021015719A2 BR112021015719A BR112021015719A BR112021015719A2 BR 112021015719 A2 BR112021015719 A2 BR 112021015719A2 BR 112021015719 A BR112021015719 A BR 112021015719A BR 112021015719 A BR112021015719 A BR 112021015719A BR 112021015719 A2 BR112021015719 A2 BR 112021015719A2
Authority
BR
Brazil
Prior art keywords
xylitol
meg
products
microorganisms
optionally
Prior art date
Application number
BR112021015719A
Other languages
English (en)
Inventor
Johannes Koch Daniel
Felipe Galzerani
Pederson Parizzi Lucas
Original Assignee
Braskem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Braskem Sa filed Critical Braskem Sa
Publication of BR112021015719A2 publication Critical patent/BR112021015719A2/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • C12P7/18Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic polyhydric
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90Isomerases (5.)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42Hydroxy-carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/001Amines; Imines
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00Preparation of nitrogen-containing organic compounds
    • C12P13/04Alpha- or beta- amino acids
    • C12P13/06Alanine; Leucine; Isoleucine; Serine; Homoserine
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P5/00Preparation of hydrocarbons or halogenated hydrocarbons
    • C12P5/02Preparation of hydrocarbons or halogenated hydrocarbons acyclic
    • C12P5/026Unsaturated compounds, i.e. alkenes, alkynes or allenes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/02Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/24Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26Ketones
    • C12P7/28Acetone-containing products
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/185Escherichia
    • C12R2001/19Escherichia coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01043Phosphogluconate 2-dehydrogenase (1.1.1.43)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y101/00Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01301D-Arabitol-phosphate dehydrogenase (1.1.1.301)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y102/00Oxidoreductases acting on the aldehyde or oxo group of donors (1.2)
    • C12Y102/01Oxidoreductases acting on the aldehyde or oxo group of donors (1.2) with NAD+ or NADP+ as acceptor (1.2.1)
    • C12Y102/01009Glyceraldehyde-3-phosphate dehydrogenase (NADP+) (1.2.1.9)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01008Phosphate acetyltransferase (2.3.1.8)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/01Phosphotransferases with an alcohol group as acceptor (2.7.1)
    • C12Y207/010116-Phosphofructokinase (2.7.1.11)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y207/00Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/02Phosphotransferases with a carboxy group as acceptor (2.7.2)
    • C12Y207/02003Phosphoglycerate kinase (2.7.2.3)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y301/00Hydrolases acting on ester bonds (3.1)
    • C12Y301/01Carboxylic ester hydrolases (3.1.1)
    • C12Y301/010316-Phosphogluconolactonase (3.1.1.31)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y401/00Carbon-carbon lyases (4.1)
    • C12Y401/02Aldehyde-lyases (4.1.2)
    • C12Y401/02022Fructose-6-phosphate phosphoketolase (4.1.2.22)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y501/00Racemaces and epimerases (5.1)
    • C12Y501/03Racemaces and epimerases (5.1) acting on carbohydrates and derivatives (5.1.3)
    • C12Y501/03001Ribulose-phosphate 3-epimerase (5.1.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y503/00Intramolecular oxidoreductases (5.3)
    • C12Y503/01Intramolecular oxidoreductases (5.3) interconverting aldoses and ketoses (5.3.1)
    • C12Y503/01006Ribose-5-phosphate isomerase (5.3.1.6)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y504/00Intramolecular transferases (5.4)
    • C12Y504/02Phosphotransferases (phosphomutases) (5.4.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

microorganismos e métodos para produção de compostosoxigenados a partir de hexoses. a invenção refere-se a micro-organismos recombinantes úteis na biossíntese de monoetileno glicol (meg), ou opcionalmente meg e um coproduto ou mais coprodutos, a partir de uma matéria-prima ou mais matérias-primas de hexose. a presente invenção refere-se também a micro-organismos recombinantes úteis na biossíntese de ácido glicólico (ga) ou, opcionalmente, ga e um coproduto ou mais coprodutos, a partir de uma matéria-prima ou mais matérias-primas de hexose. a presente invenção refere-se a micro-organismos recombinantes úteis na biossíntese de xilitol, ou opcionalmente xilitol e um coproduto ou mais coprodutos, a partir de uma matéria-prima ou mais matérias-primas de hexose. são também providos métodos de produção de meg (ou ga ou xilitol), ou opcionalmente meg (ou ga ou xilitol) e um coproduto ou mais coprodutos, a partir de uma matéria-prima ou mais matérias-primas de hexose usando os micro-organismos recombinantes, bem como composições compreendendo os micro-organismos recombinantes e/ou os produtos meg (ou ga ou xilitol) ou, opcionalmente, meg (ou ga ou xilitol) e um coproduto ou mais coprodutos.
BR112021015719A 2019-02-20 2020-02-20 Micro-organismos e métodos para produção de compostos oxigenados a partir de hexoses BR112021015719A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201962808247P 2019-02-20 2019-02-20
PCT/BR2020/050052 WO2020168407A1 (en) 2019-02-20 2020-02-20 Microorganisms and methods for the production of oxygenated compounds from hexoses

Publications (1)

Publication Number Publication Date
BR112021015719A2 true BR112021015719A2 (pt) 2021-12-14

Family

ID=70005560

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112021015719A BR112021015719A2 (pt) 2019-02-20 2020-02-20 Micro-organismos e métodos para produção de compostos oxigenados a partir de hexoses

Country Status (6)

Country Link
US (1) US12006526B2 (pt)
EP (1) EP3908663A1 (pt)
JP (1) JP7504112B2 (pt)
CN (1) CN113710807A (pt)
BR (1) BR112021015719A2 (pt)
WO (1) WO2020168407A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102233375B1 (ko) * 2018-12-11 2021-03-31 씨제이제일제당 주식회사 신규 싸이코스-6-인산의 탈인산화 효소, 이를 포함하는 싸이코스 생산용 조성물, 및 이를 이용한 싸이코스 제조방법
CN111593014B (zh) * 2020-06-24 2022-07-05 江南大学 联产1,3-丙二醇和d-1,2,4-丁三醇的方法
CN112210551A (zh) * 2020-10-15 2021-01-12 天津科技大学 一种d-阿洛酮糖-3-差向异构酶固定化酶制备方法
EP4287822A1 (en) * 2021-01-28 2023-12-13 Pioneer Hi-Bred International, Inc. Clubroot resistance in brassica
CN113447585B (zh) * 2021-06-28 2022-03-15 中国食品药品检定研究院 基于液相色谱评价体外辅助生殖用液质量的方法
WO2023220546A1 (en) * 2022-05-09 2023-11-16 Cargill, Incorporated Genetically modified yeast and fermentation processes for the production of arabitol

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW313589B (pt) 1991-12-12 1997-08-21 Wacker Chemie Gmbh
US7226761B2 (en) 1992-11-05 2007-06-05 Danisco Sweeteners Oy Manufacture of five-carbon sugars and sugar alcohols
JP4066543B2 (ja) 1998-01-12 2008-03-26 味の素株式会社 発酵法によるl−セリンの製造法
US20060110805A1 (en) 2004-05-19 2006-05-25 Biotechnology Research And Development Corporation Microbial production of xylitol via hexose phosphate and pentose phosphate intermediate
WO2007140816A1 (en) * 2006-06-09 2007-12-13 Metabolic Explorer Glycolic acid production by fermentation from renewable resources
WO2007144018A1 (en) 2006-06-12 2007-12-21 Metabolic Explorer Ethanolamine production by fermentation
DE102006027683A1 (de) 2006-06-14 2007-12-20 Siemens Ag Verfahren und Vorrichtung zur Vernetzung einer automatisierten Anlage
ES2549003T3 (es) 2008-12-31 2015-10-22 Metabolic Explorer Método para la preparación de dioles
EP2233562A1 (en) * 2009-03-24 2010-09-29 Metabolic Explorer Method for producing high amount of glycolic acid by fermentation
US8969053B2 (en) 2009-07-30 2015-03-03 Metabolic Explorer Mutant YqhD enzyme for the production of a biochemical by fermentation
KR20130093481A (ko) 2010-04-13 2013-08-22 게노마티카 인코포레이티드 에틸렌 글리콜을 생산하기 위한 미생물 및 방법
PE20140009A1 (es) 2010-10-19 2014-01-18 Global Bioenergies Produccion de alquenos mediante conversion enzimatica combinada de acidos 3-hidroxialcanoicos
WO2013066568A1 (en) 2011-10-07 2013-05-10 Danisco Us Inc. Utilization of phosphoketolase in the production of mevalonate, isoprenoid precursors, and isoprene
KR101351879B1 (ko) 2012-02-06 2014-01-22 명지대학교 산학협력단 에탄―1,2―디올 생산 미생물 및 이를 이용한 에탄―1,2―디올 생산 방법
WO2013126721A1 (en) 2012-02-23 2013-08-29 Massachusetts Institute Of Technology Engineering microbes and metabolic pathways for the production of ethylene glycol
WO2014049382A2 (en) 2012-09-26 2014-04-03 Metabolic Explorer Ethylenediamine fermentative production by a recombinant microorganism
CN104178443B (zh) * 2013-05-24 2017-04-12 中国科学院天津工业生物技术研究所 生产丁二酸的重组大肠杆菌及其应用
PL3019604T3 (pl) 2013-07-09 2021-01-25 Global Bioenergies Warianty dekarboksylazy difosfomewalonianowej
WO2015042588A1 (en) 2013-09-23 2015-03-26 Braskem S.A. Engineered enzyme having acetoacetyl-coa hydrolase activity, microorganisms comprising same, and methods of using same
FR3028529B1 (fr) * 2014-11-19 2016-12-30 Inst Nat De La Rech Agronomique Inra Procede de production d'au moins un metabolite d'interet par transformation d'un pentose dans un microorganisme
WO2017156166A1 (en) 2016-03-09 2017-09-14 Braskem S.A. Microorganisms and methods for the co-production of ethylene glycol and three carbon compounds
US20200048662A1 (en) * 2016-10-11 2020-02-13 Braskem S.A. Microorganisms and methods for the co-production of ethylene glycol and isobutene

Also Published As

Publication number Publication date
JP2022521904A (ja) 2022-04-13
US12006526B2 (en) 2024-06-11
JP7504112B2 (ja) 2024-06-21
WO2020168407A1 (en) 2020-08-27
CN113710807A (zh) 2021-11-26
US20200283806A1 (en) 2020-09-10
EP3908663A1 (en) 2021-11-17

Similar Documents

Publication Publication Date Title
BR112021015719A2 (pt) Micro-organismos e métodos para produção de compostos oxigenados a partir de hexoses
CO2018000344A2 (es) Derivados de piperidina 1,4-sustituidos
MX2023004157A (es) Composiciones de oligosacaridos para el uso como alimento para animales y sus metodos para producirlas.
MX2019004568A (es) Produccion mejorada de derivados de acidos grasos.
BR112018067323A2 (pt) micro-organismos e métodos para a coprodução de etileno glicol e três compostos de carbono
BR112014026206A2 (pt) sistemas e métodos celulares para melhorar a síntese de ácidos graxos através da expressão da desidrogenase
BRPI0923702B8 (pt) Composições inseticidas estáveis compreendendo spinosin e uma mistura esteroisomérica de sulfoxaflor, e seu método de produção
BR112013004481A2 (pt) método para a síntese de hexitóis substituídos tal como dianidrogalactitol
BR112012021865A2 (pt) derivados de ceto benzofurano, assim com o respectivo processo de síntese e os intermediários.
BR112015011466A8 (pt) Célula hospedeira fúngica recombinante, constructo de ácido nucleico recombinante, sequência de polpeptídeo isolada, e, métodos para produzir um produto de fermentação e pelo menos um produto final a partir de pelo menos um substrato celulósico
BR112014018859A8 (pt) Ração contendo ingredientes da ração adicionais e aditivos adicionais e outros agentes auxiliares, processo para preparação de uma ração, método para aumento do teor de gordura do leite e para aumento da produção de leite e ração composta de ruminantes
EA201491190A1 (ru) Способ получения hmf и производных hmf из сахаров с восстановлением непревращенных сахаров, подходящих для прямой ферментации до этанола
BR112013027340A2 (pt) processo para recuperar álcool com redução de água do topo de uma coluna de ácido
BR112015009201A2 (pt) composição compreendeendo um polipeptídeo recombinante, ácido nucleico codificando o mesmo, célula hospedeira, bem como métodos para produzir uma beta-glucosidase e para hidrolisar um substrato de biomassa lignocelulósica
AR116615A2 (es) Operaciones de cosecha mejoradas para proteínas recombinadas
BR112014026053A2 (pt) método de preparo de para-xileno a partir de biomassa
EA201691754A1 (ru) Рекомбинантный микроорганизм, экспрессирующий аналог авермектина, и его применение
BR112014030376A2 (pt) processo para a produção de lactato
ECSP17045069A (es) Recuperación de aceite de suspensión de palma
BR112012019307A2 (pt) processo para produzir composições de etanol anidras
BR112017019332A2 (pt) processos para melhorar um rendimento de glicose ou xilose de sacarificação de um material lignocelulósico e para produzir um produto de fermentação a partir de um material lignocelulósico
BR112014009984A2 (pt) método de preparação para glúten de milho fermentado
BR112014000247A8 (pt) Composição, método para degradação de uma biomassa lignocelulósica, método para produção de um produto de fermentação, método para produzir ácido glucônico, ácido xilônico e/ou ácido xilobiônico, método para aumentar a produção de ácido glucônico, ácido xilônico e/ou ácido xilobiônico, método para aumentar a produção de açúcares e uso da composição
BR112014006500A2 (pt) confeito de múltiplas regiões e método de produção do mesmo
AR064282A1 (es) Composiciones de aldehido y alcohol derivadas de aceite de semillas