CA3013336A1 - Buffer formulations for enhanced antibody stability - Google Patents
Buffer formulations for enhanced antibody stability Download PDFInfo
- Publication number
- CA3013336A1 CA3013336A1 CA3013336A CA3013336A CA3013336A1 CA 3013336 A1 CA3013336 A1 CA 3013336A1 CA 3013336 A CA3013336 A CA 3013336A CA 3013336 A CA3013336 A CA 3013336A CA 3013336 A1 CA3013336 A1 CA 3013336A1
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- CA
- Canada
- Prior art keywords
- antibody formulation
- formulation
- buffered
- antibody
- buffer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
- A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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Landscapes
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| CN106170298B (zh) | 2013-10-16 | 2024-01-09 | 前瞻疗法公司 | 用于提高抗体稳定性的缓冲液制剂 |
| ES2572919T3 (es) * | 2014-05-23 | 2016-06-03 | Ares Trading S.A. | Composición farmacéutica líquida |
| WO2016118707A1 (en) | 2015-01-21 | 2016-07-28 | Oncobiologics, Inc. | Modulation of charge variants in a monoclonal antibody composition |
| CN109563161A (zh) | 2016-02-03 | 2019-04-02 | 安口生物公司 | 用于提高抗体稳定性的缓冲制剂 |
| KR20190024572A (ko) * | 2017-08-30 | 2019-03-08 | (주)셀트리온 | TNFα 관련 질환을 치료하기 위한 피하 투여 요법 |
| US20210031012A1 (en) | 2018-01-26 | 2021-02-04 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a pde4 inhibitor |
| WO2019246312A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an immunomodulator |
| WO2019246271A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an il-12/il-23 inhibitor |
| WO2019246317A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease or condition in a tissue originating from the endoderm |
| US20230312700A1 (en) | 2018-06-20 | 2023-10-05 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a tnf inhibitor |
| WO2019246455A1 (en) | 2018-06-20 | 2019-12-26 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an integrin inhibitor |
| US12171764B2 (en) | 2018-06-20 | 2024-12-24 | Biora Therapeutics, Inc. | Treatment of a disease of the gastrointestinal tract with a JAK or other kinase inhibitor |
| KR20210102954A (ko) * | 2019-01-11 | 2021-08-20 | 삼성바이오에피스 주식회사 | 항체를 포함하는 약학적 조성물, 이를 포함하는 디바이스, 및 이의 용도 |
| KR20220064998A (ko) * | 2019-09-19 | 2022-05-19 | 이노벤트 바이오로직스 (쑤저우) 컴퍼니, 리미티드 | 콜레스테롤 관련 질환을 예방하거나 치료하기 위한 방법에 있어서 항 pcsk9 항체의 용도 |
| IL297986A (en) | 2020-05-08 | 2023-01-01 | Genmab As | Bispecific antibodies against cd3 and cd20 |
| WO2022135395A1 (zh) * | 2020-12-22 | 2022-06-30 | 百奥泰生物制药股份有限公司 | 稳定的抗体制剂及其制备方法和应用 |
| GB202115121D0 (en) * | 2021-10-21 | 2021-12-08 | Ucb Biopharma Sprl | Formulations |
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- 2017-02-01 US US16/072,991 patent/US11285210B2/en active Active
- 2017-02-01 WO PCT/US2017/016040 patent/WO2017136433A1/en not_active Ceased
- 2017-02-01 JP JP2018540113A patent/JP7084308B2/ja active Active
- 2017-02-01 CA CA3013336A patent/CA3013336A1/en active Pending
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- 2017-02-01 EP EP17705527.4A patent/EP3411401A1/en not_active Withdrawn
- 2017-02-01 AU AU2017213775A patent/AU2017213775A1/en not_active Abandoned
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| JP7084308B2 (ja) | 2022-06-14 |
| JP2019504086A (ja) | 2019-02-14 |
| WO2017136433A1 (en) | 2017-08-10 |
| EP3411401A1 (en) | 2018-12-12 |
| MX2018009341A (es) | 2019-05-15 |
| US11285210B2 (en) | 2022-03-29 |
| AU2017213775A1 (en) | 2018-08-16 |
| CN109563161A (zh) | 2019-04-02 |
| US20190030163A1 (en) | 2019-01-31 |
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