CA3001014A1 - Mrna cap analogs and methods of mrna capping - Google Patents

Mrna cap analogs and methods of mrna capping Download PDF

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Publication number
CA3001014A1
CA3001014A1 CA3001014A CA3001014A CA3001014A1 CA 3001014 A1 CA3001014 A1 CA 3001014A1 CA 3001014 A CA3001014 A CA 3001014A CA 3001014 A CA3001014 A CA 3001014A CA 3001014 A1 CA3001014 A1 CA 3001014A1
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alkyl
compound
halo
optionally substituted
independently
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Abandoned
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CA3001014A
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English (en)
French (fr)
Inventor
Gabor Butora
Matthew Stanton
Thomas Steele
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ModernaTx Inc
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ModernaTx Inc
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Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C07H19/207Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids the phosphoric or polyphosphoric acids being esterified by a further hydroxylic compound, e.g. flavine adenine dinucleotide or nicotinamide-adenine dinucleotide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals
    • C07H19/20Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA3001014A 2015-10-16 2016-10-17 Mrna cap analogs and methods of mrna capping Abandoned CA3001014A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562242881P 2015-10-16 2015-10-16
US62/242,881 2015-10-16
PCT/US2016/057405 WO2017066793A1 (en) 2015-10-16 2016-10-17 Mrna cap analogs and methods of mrna capping

Publications (1)

Publication Number Publication Date
CA3001014A1 true CA3001014A1 (en) 2017-04-20

Family

ID=57219027

Family Applications (1)

Application Number Title Priority Date Filing Date
CA3001014A Abandoned CA3001014A1 (en) 2015-10-16 2016-10-17 Mrna cap analogs and methods of mrna capping

Country Status (6)

Country Link
US (1) US20190225644A1 (enExample)
EP (1) EP3362460A1 (enExample)
JP (1) JP2018530587A (enExample)
AU (1) AU2016340183A1 (enExample)
CA (1) CA3001014A1 (enExample)
WO (1) WO2017066793A1 (enExample)

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