CA2998730A1 - Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders - Google Patents

Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders Download PDF

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Publication number
CA2998730A1
CA2998730A1 CA2998730A CA2998730A CA2998730A1 CA 2998730 A1 CA2998730 A1 CA 2998730A1 CA 2998730 A CA2998730 A CA 2998730A CA 2998730 A CA2998730 A CA 2998730A CA 2998730 A1 CA2998730 A1 CA 2998730A1
Authority
CA
Canada
Prior art keywords
amount
phentermine
administered
canagliflozin
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2998730A
Other languages
English (en)
French (fr)
Inventor
Norman R. Rosenthal
Paul ROTHENBERG
David C. Polidori
Douglas K. Ways
Peter P. STEIN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceutica NV
Original Assignee
Janssen Pharmaceutica NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica NV filed Critical Janssen Pharmaceutica NV
Publication of CA2998730A1 publication Critical patent/CA2998730A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Child & Adolescent Psychology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
CA2998730A 2015-09-15 2016-09-13 Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders Abandoned CA2998730A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201562218842P 2015-09-15 2015-09-15
US62/218,842 2015-09-15
US201662306110P 2016-03-10 2016-03-10
US62/306,110 2016-03-10
US15/262,038 2016-09-12
US15/262,038 US20170071970A1 (en) 2015-09-15 2016-09-12 Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
PCT/US2016/051435 WO2017048670A1 (en) 2015-09-15 2016-09-13 Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders

Publications (1)

Publication Number Publication Date
CA2998730A1 true CA2998730A1 (en) 2017-03-23

Family

ID=58236464

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2998730A Abandoned CA2998730A1 (en) 2015-09-15 2016-09-13 Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders

Country Status (18)

Country Link
US (3) US20170071970A1 (enExample)
EP (1) EP3349740B1 (enExample)
JP (1) JP2018527374A (enExample)
KR (1) KR20180051560A (enExample)
CN (1) CN108024977A (enExample)
AU (1) AU2016322537B2 (enExample)
CA (1) CA2998730A1 (enExample)
CO (1) CO2018002708A2 (enExample)
EA (1) EA201890738A1 (enExample)
ES (1) ES2873117T3 (enExample)
HK (1) HK1248124A1 (enExample)
IL (1) IL257876A (enExample)
MX (1) MX383002B (enExample)
PH (1) PH12018500501A1 (enExample)
TW (1) TW201722413A (enExample)
UA (1) UA122974C2 (enExample)
WO (1) WO2017048670A1 (enExample)
ZA (1) ZA201802448B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI835735B (zh) * 2017-06-12 2024-03-21 比利時商健生藥品公司 減少或預防第ii型糖尿病患者中心血管事件之方法
CN110038009B (zh) * 2019-05-13 2021-01-08 浙江大学 卡格列净在制备抗肿瘤药物中的应用
IL294521A (en) 2020-02-18 2022-09-01 Novo Nordisk As glp-1 compounds and their uses
CN112716940A (zh) * 2021-02-18 2021-04-30 苏州大学 卡格列净在制备治疗与stat6蛋白相关疾病的药物中的应用
CN113812378B (zh) * 2021-09-29 2023-02-03 湖北天勤生物技术研究院有限公司 一种食蟹猴肥胖症模型的建立方法及其应用
CN113893349B (zh) * 2021-12-13 2022-07-22 北京大学第三医院（北京大学第三临床医学院） 达格列净及其类似物在制备防治雄性生殖功能障碍的药物中的用途

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