CA2971968C - Improved methods and devices for cellular analysis - Google Patents

Improved methods and devices for cellular analysis Download PDF

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Publication number
CA2971968C
CA2971968C CA2971968A CA2971968A CA2971968C CA 2971968 C CA2971968 C CA 2971968C CA 2971968 A CA2971968 A CA 2971968A CA 2971968 A CA2971968 A CA 2971968A CA 2971968 C CA2971968 C CA 2971968C
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CA
Canada
Prior art keywords
cells
cartridge
cell
sample
needle
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2971968A
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English (en)
French (fr)
Other versions
CA2971968A1 (en
Inventor
Douglas P. Clark
Adam Schayowitz
Kathleen M. Murphy
Scott L. Diamond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biomarker Strategies LLC
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Biomarker Strategies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomarker Strategies LLC filed Critical Biomarker Strategies LLC
Publication of CA2971968A1 publication Critical patent/CA2971968A1/en
Application granted granted Critical
Publication of CA2971968C publication Critical patent/CA2971968C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10Investigating individual particles
    • G01N15/14Optical investigation techniques, e.g. flow cytometry
    • G01N15/1429Signal processing
    • G01N15/1433Signal processing using image recognition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/42Integrated assemblies, e.g. cassettes or cartridges
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/12Well or multiwell plates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/04Seals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1032Dilution or aliquotting

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Signal Processing (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
CA2971968A 2007-10-24 2008-10-24 Improved methods and devices for cellular analysis Expired - Fee Related CA2971968C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US98227907P 2007-10-24 2007-10-24
US60/982,279 2007-10-24
US9905908P 2008-09-22 2008-09-22
US61/099,059 2008-09-22
CA2703631A CA2703631C (en) 2007-10-24 2008-10-24 Improved methods and devices for cellular analysis

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2703631A Division CA2703631C (en) 2007-10-24 2008-10-24 Improved methods and devices for cellular analysis

Publications (2)

Publication Number Publication Date
CA2971968A1 CA2971968A1 (en) 2009-04-30
CA2971968C true CA2971968C (en) 2019-08-13

Family

ID=40340698

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2971968A Expired - Fee Related CA2971968C (en) 2007-10-24 2008-10-24 Improved methods and devices for cellular analysis
CA2703631A Expired - Fee Related CA2703631C (en) 2007-10-24 2008-10-24 Improved methods and devices for cellular analysis

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2703631A Expired - Fee Related CA2703631C (en) 2007-10-24 2008-10-24 Improved methods and devices for cellular analysis

Country Status (9)

Country Link
US (2) US9121801B2 (https=)
EP (2) EP2210080B1 (https=)
JP (3) JP2011501190A (https=)
KR (1) KR101658245B1 (https=)
AU (1) AU2008317329B2 (https=)
CA (2) CA2971968C (https=)
ES (1) ES2535631T3 (https=)
PL (1) PL2210080T3 (https=)
WO (1) WO2009055052A2 (https=)

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Also Published As

Publication number Publication date
JP6177841B2 (ja) 2017-08-09
JP2016001184A (ja) 2016-01-07
CA2703631A1 (en) 2009-04-30
JP2018004651A (ja) 2018-01-11
JP2011501190A (ja) 2011-01-06
AU2008317329B2 (en) 2014-10-02
US20090162853A1 (en) 2009-06-25
EP2210080B1 (en) 2015-01-28
PL2210080T3 (pl) 2015-06-30
ES2535631T3 (es) 2015-05-13
EP2210080A2 (en) 2010-07-28
CA2703631C (en) 2017-08-22
WO2009055052A3 (en) 2009-07-02
JP6675355B2 (ja) 2020-04-01
KR20100115341A (ko) 2010-10-27
US20150353880A1 (en) 2015-12-10
US9121801B2 (en) 2015-09-01
CA2971968A1 (en) 2009-04-30
WO2009055052A2 (en) 2009-04-30
KR101658245B1 (ko) 2016-09-22
EP2573541A1 (en) 2013-03-27
HK1145878A1 (en) 2011-05-06
AU2008317329A1 (en) 2009-04-30

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