CA2946650C - Adenovirus comprising an albumin-binding moiety - Google Patents
Adenovirus comprising an albumin-binding moiety Download PDFInfo
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- CA2946650C CA2946650C CA2946650A CA2946650A CA2946650C CA 2946650 C CA2946650 C CA 2946650C CA 2946650 A CA2946650 A CA 2946650A CA 2946650 A CA2946650 A CA 2946650A CA 2946650 C CA2946650 C CA 2946650C
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- adenovirus
- albumin
- adenoviral
- adenoviral genome
- protein
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10371—Demonstrated in vivo effect
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14382162.7A EP2940128A1 (en) | 2014-04-30 | 2014-04-30 | Adenovirus comprising an albumin-binding moiety |
| EP14382162.7 | 2014-04-30 | ||
| PCT/EP2015/059593 WO2015166082A1 (en) | 2014-04-30 | 2015-04-30 | Adenovirus comprising an albumin-binding moiety |
Publications (2)
| Publication Number | Publication Date |
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| CA2946650A1 CA2946650A1 (en) | 2015-11-05 |
| CA2946650C true CA2946650C (en) | 2023-07-11 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2946650A Active CA2946650C (en) | 2014-04-30 | 2015-04-30 | Adenovirus comprising an albumin-binding moiety |
Country Status (12)
| Country | Link |
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| US (3) | US10604549B2 (enExample) |
| EP (2) | EP2940128A1 (enExample) |
| JP (1) | JP6639412B2 (enExample) |
| KR (1) | KR102628234B1 (enExample) |
| CN (1) | CN106471125B (enExample) |
| AU (1) | AU2015254535B2 (enExample) |
| BR (1) | BR112016025297B1 (enExample) |
| CA (1) | CA2946650C (enExample) |
| IL (1) | IL248590B (enExample) |
| MX (1) | MX381286B (enExample) |
| RU (1) | RU2711371C2 (enExample) |
| WO (1) | WO2015166082A1 (enExample) |
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| CA2903582C (en) | 2013-03-14 | 2021-06-08 | Salk Institute For Biological Studies | Oncolytic adenovirus compositions |
| EP2940128A1 (en) | 2014-04-30 | 2015-11-04 | Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Adenovirus comprising an albumin-binding moiety |
| WO2017147265A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| JP7015551B2 (ja) | 2016-02-23 | 2022-02-15 | ソーク インスティテュート フォー バイオロジカル スタディーズ | ウイルス動態への影響を最小限にするための治療用アデノウイルスにおける外因性遺伝子発現 |
| CA3045892A1 (en) | 2016-12-12 | 2018-06-21 | Salk Institute For Biological Studies | Tumor-targeting synthetic adenoviruses and uses thereof |
| US11077199B2 (en) | 2017-08-09 | 2021-08-03 | Massachusetts Institute Of Technology | Albumin binding peptide conjugates and methods thereof |
| US20200330581A1 (en) * | 2017-10-09 | 2020-10-22 | Keith Black | Oncolytic cancer immunotherapies and methods of use |
| CN112004923A (zh) | 2017-11-22 | 2020-11-27 | 迈索布拉斯特国际有限公司 | 细胞组合物及治疗方法 |
| BR112020019942A2 (pt) | 2018-04-09 | 2021-01-26 | Salk Institute For Biological Studies | composições de adenovírus oncolítico com propriedades de replicação aprimoradas |
| US20210340279A1 (en) | 2018-08-31 | 2021-11-04 | Yale University | Compositions and methods of using cell-penetrating antibodies in combination with immune checkpoint modulators |
| CN119955743A (zh) * | 2018-09-10 | 2025-05-09 | 上海锦斯生物技术有限公司 | 修饰的溶瘤病毒、其组合物和用途 |
| EP3906038A4 (en) | 2018-11-21 | 2022-06-01 | Mayo Foundation for Medical Education and Research | ADENOVIRUS AND METHODS OF USE OF ADENOVIRUS |
| EP3911671A1 (en) | 2019-04-29 | 2021-11-24 | Mayo Foundation for Medical Education and Research | Multivalent pd-l1 binding compounds for treating cancer |
| CA3149478A1 (en) | 2019-08-05 | 2021-02-11 | Mesoblast International Sarl | Cellular compositions comprising viral vectors and methods of treatment |
| WO2021194183A1 (ko) * | 2020-03-25 | 2021-09-30 | ㈜큐리진 | 면역 회피성 항종양 아데노바이러스 |
| CN115996735A (zh) | 2020-08-10 | 2023-04-21 | 迈索布拉斯特国际有限公司 | 细胞组合物和治疗方法 |
| CN116271066A (zh) * | 2021-12-13 | 2023-06-23 | 康希诺生物股份公司 | 一种重组腺病毒载体疫苗吸入给药递送系统 |
| CN114159556B (zh) * | 2021-12-14 | 2023-06-16 | 中国人民解放军军事科学院军事医学研究院 | 一种用于腺病毒载体疫苗免疫增强的蛋白质纳米递送载体 |
| KR20230095830A (ko) * | 2021-12-21 | 2023-06-29 | (주)큐리진 | 면역 회피성 항종양 아데노바이러스 |
| WO2023120762A1 (ko) * | 2021-12-21 | 2023-06-29 | (주)큐리진 | 면역 회피성 항종양 아데노바이러스 |
| EP4602078A2 (en) | 2022-10-11 | 2025-08-20 | Yale University | Compositions and methods of using cell-penetrating antibodies |
| CN115624524B (zh) * | 2022-10-25 | 2023-10-27 | 中国医科大学附属第一医院 | Peg化白蛋白修饰的溶瘤病毒静脉递送制剂的制备及其应用 |
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| AU561343B2 (en) | 1981-10-19 | 1987-05-07 | Genentech Inc. | Human immune interferon by recombinant dna |
| DE3377363D1 (en) | 1982-03-31 | 1988-08-18 | Ajinomoto Kk | Gene coding for interleukin-2 polypeptide, recombinant dna carrying said gene, cell lines possessing the recombinant dna,and method for producing interleukin-2 using said cells |
| US4677063A (en) | 1985-05-02 | 1987-06-30 | Cetus Corporation | Human tumor necrosis factor |
| US5391485A (en) | 1985-08-06 | 1995-02-21 | Immunex Corporation | DNAs encoding analog GM-CSF molecules displaying resistance to proteases which cleave at adjacent dibasic residues |
| US5328988A (en) | 1987-10-26 | 1994-07-12 | Immunex Corporation | Interleukin-7 |
| US4965195A (en) | 1987-10-26 | 1990-10-23 | Immunex Corp. | Interleukin-7 |
| US5457038A (en) | 1988-11-10 | 1995-10-10 | Genetics Institute, Inc. | Natural killer stimulatory factor |
| KR970005042B1 (ko) | 1993-02-09 | 1997-04-11 | 한일합성섬유공업 주식회사 | 종양괴사인자-알파 뮤테인 |
| US5846945A (en) | 1993-02-16 | 1998-12-08 | Onyx Pharmaceuticals, Inc. | Cytopathic viruses for therapy and prophylaxis of neoplasia |
| US5641665A (en) | 1994-11-28 | 1997-06-24 | Vical Incorporated | Plasmids suitable for IL-2 expression |
| US5998205A (en) | 1994-11-28 | 1999-12-07 | Genetic Therapy, Inc. | Vectors for tissue-specific replication |
| WO2001045746A2 (en) * | 1999-12-24 | 2001-06-28 | Genentech, Inc. | Methods and compositions for prolonging elimination half-times of bioactive compounds |
| EP1284294A4 (en) | 2000-05-26 | 2004-10-13 | Sumitomo Pharma | RECOMBINANT ADENOVIRUS WITH REDUCED SIDE EFFECTS (12/05/01) |
| GB0017720D0 (en) | 2000-07-19 | 2000-09-06 | Got A Gene Ab | Modified virus |
| WO2007050128A2 (en) * | 2005-05-31 | 2007-05-03 | Vectorlogics, Inc. | Shielded adenoviral vectors and methods of use |
| US20090074810A1 (en) | 2006-04-28 | 2009-03-19 | The Trustees Of The University Of Pennsylvania | Modified Adenovirus Hexon Protein and Uses Thereof |
| RU2557319C2 (ru) | 2007-07-16 | 2015-07-20 | Дженентек, Инк. | ГУМАНИЗИРОВАННЫЕ АНТИТЕЛА ПРОТИВ CD79b И ИММУНОКОНЪЮГАТЫ И СПОСОБЫ ПРИМЕНЕНИЯ |
| CN101781636A (zh) | 2009-01-19 | 2010-07-21 | 中国人民解放军第二军医大学东方肝胆外科医院 | 一种含11型腺病毒纤毛蛋白基因的增殖型重组溶瘤腺病毒、其构建方法及其用途 |
| ES2385251B1 (es) | 2009-05-06 | 2013-05-06 | Fundació Privada Institut D'investigació Biomèdica De Bellvitge | Adenovirus oncolíticos para el tratamiento del cáncer. |
| CN102844329B (zh) | 2010-04-14 | 2016-01-20 | 财团法人牧岩生命工学研究所 | 分离自猿腺病毒血清型19的六邻体、其高变区和使用其的嵌合型腺病毒 |
| EP2940128A1 (en) | 2014-04-30 | 2015-11-04 | Institut d'Investigació Biomèdica de Bellvitge (IDIBELL) | Adenovirus comprising an albumin-binding moiety |
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2014
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2015
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- 2015-04-30 WO PCT/EP2015/059593 patent/WO2015166082A1/en not_active Ceased
- 2015-04-30 BR BR112016025297-7A patent/BR112016025297B1/pt active IP Right Grant
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- 2015-04-30 US US15/307,408 patent/US10604549B2/en active Active
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- 2015-04-30 KR KR1020167033433A patent/KR102628234B1/ko active Active
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| CN106471125B (zh) | 2021-04-06 |
| RU2016146664A (ru) | 2018-05-30 |
| IL248590B (en) | 2021-01-31 |
| US20170051022A1 (en) | 2017-02-23 |
| IL248590A0 (en) | 2016-12-29 |
| AU2015254535A1 (en) | 2016-12-01 |
| AU2015254535B2 (en) | 2020-08-13 |
| RU2016146664A3 (enExample) | 2018-06-28 |
| RU2711371C2 (ru) | 2020-01-16 |
| EP3137599A1 (en) | 2017-03-08 |
| WO2015166082A1 (en) | 2015-11-05 |
| US10604549B2 (en) | 2020-03-31 |
| MX381286B (es) | 2025-03-12 |
| EP2940128A1 (en) | 2015-11-04 |
| JP2017514483A (ja) | 2017-06-08 |
| BR112016025297B1 (pt) | 2022-08-30 |
| BR112016025297A2 (pt) | 2017-10-17 |
| CN106471125A (zh) | 2017-03-01 |
| US11578104B2 (en) | 2023-02-14 |
| MX2016014187A (es) | 2017-05-03 |
| KR102628234B1 (ko) | 2024-01-22 |
| JP6639412B2 (ja) | 2020-02-05 |
| CA2946650A1 (en) | 2015-11-05 |
| US20200181208A1 (en) | 2020-06-11 |
| US20230331786A1 (en) | 2023-10-19 |
| KR20160145825A (ko) | 2016-12-20 |
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