CA2929686C - Modified kz144 endolysin sequence - Google Patents
Modified kz144 endolysin sequence Download PDFInfo
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- CA2929686C CA2929686C CA2929686A CA2929686A CA2929686C CA 2929686 C CA2929686 C CA 2929686C CA 2929686 A CA2929686 A CA 2929686A CA 2929686 A CA2929686 A CA 2929686A CA 2929686 C CA2929686 C CA 2929686C
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
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- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
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- Proteomics, Peptides & Aminoacids (AREA)
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- Communicable Diseases (AREA)
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- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP2013/073869 | 2013-11-14 | ||
| PCT/EP2013/073869 WO2015070911A1 (en) | 2013-11-14 | 2013-11-14 | Modified kz144 endolysin sequence |
| PCT/EP2014/074671 WO2015071436A1 (en) | 2013-11-14 | 2014-11-14 | Modified kz144 endolysin sequence |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2929686A1 CA2929686A1 (en) | 2015-05-21 |
| CA2929686C true CA2929686C (en) | 2023-08-08 |
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| EP4151228A3 (en) | 2015-09-17 | 2023-06-14 | Contrafect Corporation | Lysin polypeptides active against gram-negative bacteria |
| CN109072211B (zh) * | 2016-04-28 | 2023-10-27 | 莱桑多股份公司 | 抗沙门氏菌的抗菌剂 |
| EP3464583A1 (en) | 2016-05-27 | 2019-04-10 | Sasinapas Co., Ltd. | Endolysin variant |
| WO2018100408A1 (en) * | 2016-11-30 | 2018-06-07 | Sasinapas Co.,Ltd. | Modified peptides |
| US11208643B2 (en) * | 2017-04-03 | 2021-12-28 | Sasinapas Co., Ltd. | Engineered gram-negative endolysins |
| EP3802620A1 (en) * | 2018-05-30 | 2021-04-14 | Lysando AG | Novel antimicrobial fusion proteins |
| CN111304181B (zh) * | 2020-02-17 | 2021-11-23 | 华东理工大学 | 一种基因工程改造后的副溶血性弧菌噬菌体裂解酶及其制备方法和应用 |
| KR20250044545A (ko) | 2023-09-23 | 2025-04-01 | 조배근 | 사료급이기 청소기 |
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| CA1289092C (en) * | 1987-01-15 | 1991-09-17 | Robert A. Hallewell | Thermostable human cu/zn superoxide dismutase muteins |
| EP0285123A3 (en) | 1987-04-03 | 1989-02-01 | Stabra AG | A method for complete mutagenesis of nucleic acids |
| ZA936811B (en) * | 1992-10-28 | 1995-03-15 | Upjohn Co | Somatotropin modifications |
| JPH08127540A (ja) * | 1994-09-09 | 1996-05-21 | Takeda Chem Ind Ltd | 抗潰瘍医薬 |
| JP2010536354A (ja) * | 2007-08-22 | 2010-12-02 | ヒグロス インベスト ゲーエムベーハー | ヒトおよび動物のブドウ球菌（Ｓｔａｐｈｙｌｏｃｏｃｃｕｓ）感染症において使用するための新しいタンパク質 |
| GB0815484D0 (en) * | 2008-08-26 | 2008-10-01 | Univ Leuven Kath | Antibacterial agents |
| SG177370A1 (en) * | 2009-06-26 | 2012-02-28 | Univ Leuven Kath | Antimicrobial agents |
| BRPI1015203B1 (pt) | 2009-06-26 | 2021-06-01 | Lysando Ag | Proteína de fusão composta por uma endolisina e uma extensão de peptídeo anfifática, usos da mesma e composição farmacêutica que compreende a dita proteína |
| EP2470648B1 (en) * | 2009-08-24 | 2019-04-10 | Katholieke Universiteit Leuven K.U. Leuven R&D | New endolysin obpgplys |
| MX340520B (es) * | 2010-04-27 | 2016-07-12 | Lysando Ag * | Metodo de reduccion de biopeliculas. |
| GB201018518D0 (en) * | 2010-11-03 | 2010-12-15 | Univ Leuven Kath | Novel endolysin |
| EP2468856A1 (en) | 2010-12-23 | 2012-06-27 | Lysando Aktiengesellschaft | Antimicrobial Agents |
| KR20130142837A (ko) * | 2012-06-20 | 2013-12-30 | 한국외국어대학교 연구산학협력단 | 슈도모나스 에루기노사의 박테리오파아지 및 그 용도 |
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- 2014-11-14 US US15/036,569 patent/US10184120B2/en active Active
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2016537979A (ja) | 2016-12-08 |
| AU2014350104B2 (en) | 2020-03-05 |
| EA035959B1 (ru) | 2020-09-07 |
| MX2016006277A (es) | 2017-01-05 |
| CN105793419A (zh) | 2016-07-20 |
| NZ719338A (en) | 2022-03-25 |
| WO2015070911A1 (en) | 2015-05-21 |
| EA201691004A1 (ru) | 2017-01-30 |
| JP6745720B2 (ja) | 2020-08-26 |
| US10184120B2 (en) | 2019-01-22 |
| WO2015071436A1 (en) | 2015-05-21 |
| BR112016011091A2 (pt) | 2017-12-05 |
| CA2929686A1 (en) | 2015-05-21 |
| US20160281074A1 (en) | 2016-09-29 |
| CN105793419B (zh) | 2021-06-01 |
| AU2014350104A1 (en) | 2016-05-12 |
| KR20160085342A (ko) | 2016-07-15 |
| BR112016011091B1 (pt) | 2024-02-06 |
| MX374403B (es) | 2025-03-06 |
| KR102302044B1 (ko) | 2021-09-15 |
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