BR112016011091B1 - Sequência de endolisina kz144 modificada - Google Patents
Sequência de endolisina kz144 modificada Download PDFInfo
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- BR112016011091B1 BR112016011091B1 BR112016011091-9A BR112016011091A BR112016011091B1 BR 112016011091 B1 BR112016011091 B1 BR 112016011091B1 BR 112016011091 A BR112016011091 A BR 112016011091A BR 112016011091 B1 BR112016011091 B1 BR 112016011091B1
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Classifications
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2462—Lysozyme (3.2.1.17)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y302/00—Hydrolases acting on glycosyl compounds, i.e. glycosylases (3.2)
- C12Y302/01—Glycosidases, i.e. enzymes hydrolysing O- and S-glycosyl compounds (3.2.1)
- C12Y302/01017—Lysozyme (3.2.1.17)
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
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- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
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- Biotechnology (AREA)
- Biomedical Technology (AREA)
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- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EPPCT/EP2013/073869 | 2013-11-14 | ||
| PCT/EP2013/073869 WO2015070911A1 (en) | 2013-11-14 | 2013-11-14 | Modified kz144 endolysin sequence |
| PCT/EP2014/074671 WO2015071436A1 (en) | 2013-11-14 | 2014-11-14 | Modified kz144 endolysin sequence |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112016011091A2 BR112016011091A2 (pt) | 2017-12-05 |
| BR112016011091B1 true BR112016011091B1 (pt) | 2024-02-06 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112016011091-9A BR112016011091B1 (pt) | 2013-11-14 | 2014-11-14 | Sequência de endolisina kz144 modificada |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US10184120B2 (enExample) |
| JP (1) | JP6745720B2 (enExample) |
| KR (1) | KR102302044B1 (enExample) |
| CN (1) | CN105793419B (enExample) |
| AU (1) | AU2014350104B2 (enExample) |
| BR (1) | BR112016011091B1 (enExample) |
| CA (1) | CA2929686C (enExample) |
| EA (1) | EA035959B1 (enExample) |
| MX (1) | MX374403B (enExample) |
| WO (2) | WO2015070911A1 (enExample) |
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| CN116077630A (zh) | 2015-09-17 | 2023-05-09 | 抗非特公司 | 具有对抗革兰氏阴性菌的活性的溶素多肽 |
| US20190125897A1 (en) * | 2016-04-28 | 2019-05-02 | Lysando Ag | Antimicrobial agents against salmonella bacteria |
| EP3464583A1 (en) | 2016-05-27 | 2019-04-10 | Sasinapas Co., Ltd. | Endolysin variant |
| WO2018100408A1 (en) | 2016-11-30 | 2018-06-07 | Sasinapas Co.,Ltd. | Modified peptides |
| KR20200012844A (ko) * | 2017-04-03 | 2020-02-05 | 사시나파스 컴퍼니 리미티드 | 조작된 그람-음성 엔도리신 |
| JP7515409B2 (ja) * | 2018-05-30 | 2024-07-12 | ライサンド アーゲー | 新規抗微生物融合タンパク質 |
| CN111304181B (zh) * | 2020-02-17 | 2021-11-23 | 华东理工大学 | 一种基因工程改造后的副溶血性弧菌噬菌体裂解酶及其制备方法和应用 |
| KR20250044545A (ko) | 2023-09-23 | 2025-04-01 | 조배근 | 사료급이기 청소기 |
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| CA1289092C (en) * | 1987-01-15 | 1991-09-17 | Robert A. Hallewell | Thermostable human cu/zn superoxide dismutase muteins |
| EP0285123A3 (en) | 1987-04-03 | 1989-02-01 | Stabra AG | A method for complete mutagenesis of nucleic acids |
| ZA936811B (en) * | 1992-10-28 | 1995-03-15 | Upjohn Co | Somatotropin modifications |
| JPH08127540A (ja) * | 1994-09-09 | 1996-05-21 | Takeda Chem Ind Ltd | 抗潰瘍医薬 |
| US8058225B2 (en) * | 2007-08-22 | 2011-11-15 | Hyglos Invest Gmbh | Proteins for use in human and animal Staphylococcus infections |
| GB0815484D0 (en) * | 2008-08-26 | 2008-10-01 | Univ Leuven Kath | Antibacterial agents |
| CA2764131C (en) * | 2009-06-26 | 2022-05-10 | Katholieke Universiteit Leuven, K.U. Leuven R&D | Antimicrobial agents |
| BRPI1015203B1 (pt) | 2009-06-26 | 2021-06-01 | Lysando Ag | Proteína de fusão composta por uma endolisina e uma extensão de peptídeo anfifática, usos da mesma e composição farmacêutica que compreende a dita proteína |
| JP5847081B2 (ja) * | 2009-08-24 | 2016-01-20 | カトリック ユニバーシテイト ルーベン ケイ．ユー． ルーベン アール アンド ディー | エンドリシンＯＢＰｇｐＬＹＳ |
| SG184836A1 (en) * | 2010-04-27 | 2012-11-29 | Lysando Ag | Method of reducing biofilms |
| GB201018518D0 (en) * | 2010-11-03 | 2010-12-15 | Univ Leuven Kath | Novel endolysin |
| EP2468856A1 (en) | 2010-12-23 | 2012-06-27 | Lysando Aktiengesellschaft | Antimicrobial Agents |
| KR20130142837A (ko) * | 2012-06-20 | 2013-12-30 | 한국외국어대학교 연구산학협력단 | 슈도모나스 에루기노사의 박테리오파아지 및 그 용도 |
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- 2014-11-14 EA EA201691004A patent/EA035959B1/ru not_active IP Right Cessation
- 2014-11-14 WO PCT/EP2014/074671 patent/WO2015071436A1/en not_active Ceased
- 2014-11-14 CN CN201480062330.1A patent/CN105793419B/zh active Active
- 2014-11-14 KR KR1020167015821A patent/KR102302044B1/ko active Active
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- 2014-11-14 MX MX2016006277A patent/MX374403B/es active IP Right Grant
- 2014-11-14 US US15/036,569 patent/US10184120B2/en active Active
- 2014-11-14 AU AU2014350104A patent/AU2014350104B2/en active Active
- 2014-11-14 CA CA2929686A patent/CA2929686C/en active Active
- 2014-11-14 JP JP2016531660A patent/JP6745720B2/ja active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP6745720B2 (ja) | 2020-08-26 |
| US10184120B2 (en) | 2019-01-22 |
| CN105793419B (zh) | 2021-06-01 |
| AU2014350104A1 (en) | 2016-05-12 |
| NZ719338A (en) | 2022-03-25 |
| KR20160085342A (ko) | 2016-07-15 |
| WO2015071436A1 (en) | 2015-05-21 |
| MX374403B (es) | 2025-03-06 |
| CA2929686C (en) | 2023-08-08 |
| KR102302044B1 (ko) | 2021-09-15 |
| BR112016011091A2 (pt) | 2017-12-05 |
| US20160281074A1 (en) | 2016-09-29 |
| JP2016537979A (ja) | 2016-12-08 |
| CA2929686A1 (en) | 2015-05-21 |
| MX2016006277A (es) | 2017-01-05 |
| AU2014350104B2 (en) | 2020-03-05 |
| EA201691004A1 (ru) | 2017-01-30 |
| CN105793419A (zh) | 2016-07-20 |
| WO2015070911A1 (en) | 2015-05-21 |
| EA035959B1 (ru) | 2020-09-07 |
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