CA2900050A1 - Methods for producing diketopiperazines and compositions containing diketopiperazines - Google Patents

Methods for producing diketopiperazines and compositions containing diketopiperazines Download PDF

Info

Publication number
CA2900050A1
CA2900050A1 CA2900050A CA2900050A CA2900050A1 CA 2900050 A1 CA2900050 A1 CA 2900050A1 CA 2900050 A CA2900050 A CA 2900050A CA 2900050 A CA2900050 A CA 2900050A CA 2900050 A1 CA2900050 A1 CA 2900050A1
Authority
CA
Canada
Prior art keywords
albumin
dkp
stream
composition
hsa
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2900050A
Other languages
English (en)
French (fr)
Inventor
David Bar-Or
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ampio Pharmaceuticals Inc
Original Assignee
Ampio Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ampio Pharmaceuticals Inc filed Critical Ampio Pharmaceuticals Inc
Publication of CA2900050A1 publication Critical patent/CA2900050A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38—Albumins
    • A61K38/385—Serum albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biomedical Technology (AREA)
CA2900050A 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines Abandoned CA2900050A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361759922P 2013-02-01 2013-02-01
US61/759,922 2013-02-01
PCT/US2014/014478 WO2014121210A1 (en) 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines

Publications (1)

Publication Number Publication Date
CA2900050A1 true CA2900050A1 (en) 2014-08-07

Family

ID=51263032

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2900050A Abandoned CA2900050A1 (en) 2013-02-01 2014-02-03 Methods for producing diketopiperazines and compositions containing diketopiperazines

Country Status (15)

Country Link
US (1) US20150366932A1 (cg-RX-API-DMAC7.html)
EP (1) EP2950811A4 (cg-RX-API-DMAC7.html)
JP (1) JP6387019B2 (cg-RX-API-DMAC7.html)
KR (1) KR20150114984A (cg-RX-API-DMAC7.html)
CN (1) CN105188737A (cg-RX-API-DMAC7.html)
AU (1) AU2014212095B2 (cg-RX-API-DMAC7.html)
BR (1) BR112015017958A2 (cg-RX-API-DMAC7.html)
CA (1) CA2900050A1 (cg-RX-API-DMAC7.html)
EA (1) EA030414B1 (cg-RX-API-DMAC7.html)
HK (1) HK1214772A1 (cg-RX-API-DMAC7.html)
IL (1) IL240125A0 (cg-RX-API-DMAC7.html)
MX (1) MX2015009908A (cg-RX-API-DMAC7.html)
PH (1) PH12015501705A1 (cg-RX-API-DMAC7.html)
SG (2) SG10201706213RA (cg-RX-API-DMAC7.html)
WO (1) WO2014121210A1 (cg-RX-API-DMAC7.html)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2774959C (en) 2000-08-04 2016-05-31 Dmi Biosciences, Inc. Method of using diketopiperazines and composition containing them
EP2517722B1 (en) 2003-05-15 2016-03-02 Ampio Pharmaceuticals, Inc. Synthesis of diketopiperazines
JP5856843B2 (ja) 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
PH12014500686A1 (en) 2011-10-10 2020-12-18 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
EA028343B1 (ru) 2011-10-10 2017-11-30 Ампио Фармасьютикалз, Инк. Лечение дегенеративного заболевания сустава
MX355446B (es) 2011-10-28 2018-04-18 Ampio Pharmaceuticals Inc Tratamiento de rinitis.
US9808454B2 (en) 2013-03-15 2017-11-07 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
EP3183240A4 (en) 2014-08-18 2018-06-27 Ampio Pharmaceuticals, Inc. Treatment of joint conditions
EP3310375A4 (en) * 2015-06-22 2019-02-20 Ampio Pharmaceuticals, Inc. USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES
US10456423B2 (en) 2016-06-13 2019-10-29 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
US10426796B2 (en) * 2016-06-13 2019-10-01 SMART SURGICAL, Inc. Compositions for biological systems and methods for preparing and using the same
US20210016273A1 (en) * 2019-07-19 2021-01-21 University Of Utah Research Foundation Rapid sperm separation based on sperm morphology and motility
WO2021163693A1 (en) * 2020-02-16 2021-08-19 Pur Biologics, Inc. Methods of manufacturing extracellular matrix using aspartyl alanyl diketopiperazine (da-dkp)

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE765030A (fr) * 1970-04-02 1971-08-16 Snam Progetti Composes contenant un noyau de dicetopiperazine et leur procedede fabrication
US5561115A (en) * 1994-08-10 1996-10-01 Bayer Corporation Low temperature albumin fractionation using sodium caprylate as a partitioning agent
US5811241A (en) * 1995-09-13 1998-09-22 Cortech, Inc. Method for preparing and identifying N-substitued 1,4-piperazines and N-substituted 1,4-piperazinediones
JP2000005569A (ja) * 1998-06-24 2000-01-11 Asahi Chem Ind Co Ltd 直列多段濾過法
CA2774959C (en) * 2000-08-04 2016-05-31 Dmi Biosciences, Inc. Method of using diketopiperazines and composition containing them
CN1791420A (zh) * 2003-05-15 2006-06-21 Dmi生物科学公司 T－细胞介导的疾病的治疗
EP2517722B1 (en) * 2003-05-15 2016-03-02 Ampio Pharmaceuticals, Inc. Synthesis of diketopiperazines
US7790039B2 (en) * 2003-11-24 2010-09-07 Northwest Biotherapeutics, Inc. Tangential flow filtration devices and methods for stem cell enrichment
US20050197496A1 (en) * 2004-03-04 2005-09-08 Gtc Biotherapeutics, Inc. Methods of protein fractionation using high performance tangential flow filtration
DK1786273T3 (en) * 2004-08-20 2019-02-18 Prometic Biosciences Ltd SEQUENTIAL PROTEIN INSULATION AND PURIFICATION PLANS WITH AFFINITY CHROMATOGRAPHY
CN102741280B (zh) * 2009-10-30 2015-12-02 诺维信生物制药丹麦公司 白蛋白变体
WO2012174472A1 (en) * 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
EA028343B1 (ru) * 2011-10-10 2017-11-30 Ампио Фармасьютикалз, Инк. Лечение дегенеративного заболевания сустава
PH12014500686A1 (en) * 2011-10-10 2020-12-18 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
MX355446B (es) * 2011-10-28 2018-04-18 Ampio Pharmaceuticals Inc Tratamiento de rinitis.

Also Published As

Publication number Publication date
SG11201505715RA (en) 2015-08-28
PH12015501705A1 (en) 2015-10-12
MX2015009908A (es) 2015-09-24
CN105188737A (zh) 2015-12-23
EP2950811A1 (en) 2015-12-09
US20150366932A1 (en) 2015-12-24
WO2014121210A1 (en) 2014-08-07
AU2014212095B2 (en) 2018-07-26
BR112015017958A2 (pt) 2017-07-11
EP2950811A4 (en) 2016-06-08
AU2014212095A1 (en) 2015-09-10
EA030414B1 (ru) 2018-08-31
JP6387019B2 (ja) 2018-09-05
HK1214772A1 (zh) 2016-08-05
JP2016511238A (ja) 2016-04-14
SG10201706213RA (en) 2017-09-28
EA201500783A1 (ru) 2016-05-31
IL240125A0 (en) 2015-09-24
KR20150114984A (ko) 2015-10-13

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20200204

FZDE Discontinued

Effective date: 20200204