PH12015501705A1 - Methods for producing diketopiperazines and compositions containing diketopiperazines - Google Patents
Methods for producing diketopiperazines and compositions containing diketopiperazinesInfo
- Publication number
- PH12015501705A1 PH12015501705A1 PH12015501705A PH12015501705A PH12015501705A1 PH 12015501705 A1 PH12015501705 A1 PH 12015501705A1 PH 12015501705 A PH12015501705 A PH 12015501705A PH 12015501705 A PH12015501705 A PH 12015501705A PH 12015501705 A1 PH12015501705 A1 PH 12015501705A1
- Authority
- PH
- Philippines
- Prior art keywords
- dkp
- albumin
- diketopiperazines
- methods
- compositions
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 5
- 238000000034 method Methods 0.000 title abstract 3
- 102000009027 Albumins Human genes 0.000 abstract 6
- 108010088751 Albumins Proteins 0.000 abstract 6
- 230000001225 therapeutic effect Effects 0.000 abstract 3
- 102000016622 Dipeptidyl Peptidase 4 Human genes 0.000 abstract 2
- 101000930822 Giardia intestinalis Dipeptidyl-peptidase 4 Proteins 0.000 abstract 2
- RVLCUCVJZVRNDC-IMJSIDKUSA-N 2-[(2s,5s)-5-methyl-3,6-dioxopiperazin-2-yl]acetic acid Chemical compound C[C@@H]1NC(=O)[C@H](CC(O)=O)NC1=O RVLCUCVJZVRNDC-IMJSIDKUSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 125000001429 N-terminal alpha-amino-acid group Chemical group 0.000 abstract 1
- 108010038239 aspartyl-alanyl-diketopiperazine Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/05—Dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
- A61K38/385—Serum albumin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/06—Preparation of peptides or proteins produced by the hydrolysis of a peptide bond, e.g. hydrolysate products
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Biomedical Technology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361759922P | 2013-02-01 | 2013-02-01 | |
| PCT/US2014/014478 WO2014121210A1 (en) | 2013-02-01 | 2014-02-03 | Methods for producing diketopiperazines and compositions containing diketopiperazines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PH12015501705A1 true PH12015501705A1 (en) | 2015-10-12 |
Family
ID=51263032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PH12015501705A PH12015501705A1 (en) | 2013-02-01 | 2015-07-31 | Methods for producing diketopiperazines and compositions containing diketopiperazines |
Country Status (15)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2774959C (en) | 2000-08-04 | 2016-05-31 | Dmi Biosciences, Inc. | Method of using diketopiperazines and composition containing them |
| EP2517722B1 (en) | 2003-05-15 | 2016-03-02 | Ampio Pharmaceuticals, Inc. | Synthesis of diketopiperazines |
| JP5856843B2 (ja) | 2008-05-27 | 2016-02-10 | アンピオ ファーマシューティカルズ，インコーポレイテッド | ジケトピペラジンを用いた医薬組成物 |
| PH12014500686A1 (en) | 2011-10-10 | 2020-12-18 | Ampio Pharmaceuticals Inc | Implantable medical devices with increased immune tolerance, and methods for making and implanting |
| EA028343B1 (ru) | 2011-10-10 | 2017-11-30 | Ампио Фармасьютикалз, Инк. | Лечение дегенеративного заболевания сустава |
| MX355446B (es) | 2011-10-28 | 2018-04-18 | Ampio Pharmaceuticals Inc | Tratamiento de rinitis. |
| US9808454B2 (en) | 2013-03-15 | 2017-11-07 | Ampio Pharmaceuticals, Inc. | Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same |
| EP3183240A4 (en) | 2014-08-18 | 2018-06-27 | Ampio Pharmaceuticals, Inc. | Treatment of joint conditions |
| EP3310375A4 (en) * | 2015-06-22 | 2019-02-20 | Ampio Pharmaceuticals, Inc. | USE OF LOW-MOLECULAR FRACTIONS OF HUMAN SERUMALBUMINE IN THE TREATMENT OF ILLNESSES |
| US10456423B2 (en) | 2016-06-13 | 2019-10-29 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
| US10426796B2 (en) * | 2016-06-13 | 2019-10-01 | SMART SURGICAL, Inc. | Compositions for biological systems and methods for preparing and using the same |
| US20210016273A1 (en) * | 2019-07-19 | 2021-01-21 | University Of Utah Research Foundation | Rapid sperm separation based on sperm morphology and motility |
| WO2021163693A1 (en) * | 2020-02-16 | 2021-08-19 | Pur Biologics, Inc. | Methods of manufacturing extracellular matrix using aspartyl alanyl diketopiperazine (da-dkp) |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE765030A (fr) * | 1970-04-02 | 1971-08-16 | Snam Progetti | Composes contenant un noyau de dicetopiperazine et leur procedede fabrication |
| US5561115A (en) * | 1994-08-10 | 1996-10-01 | Bayer Corporation | Low temperature albumin fractionation using sodium caprylate as a partitioning agent |
| US5811241A (en) * | 1995-09-13 | 1998-09-22 | Cortech, Inc. | Method for preparing and identifying N-substitued 1,4-piperazines and N-substituted 1,4-piperazinediones |
| JP2000005569A (ja) * | 1998-06-24 | 2000-01-11 | Asahi Chem Ind Co Ltd | 直列多段濾過法 |
| CA2774959C (en) * | 2000-08-04 | 2016-05-31 | Dmi Biosciences, Inc. | Method of using diketopiperazines and composition containing them |
| CN1791420A (zh) * | 2003-05-15 | 2006-06-21 | Dmi生物科学公司 | T－细胞介导的疾病的治疗 |
| EP2517722B1 (en) * | 2003-05-15 | 2016-03-02 | Ampio Pharmaceuticals, Inc. | Synthesis of diketopiperazines |
| US7790039B2 (en) * | 2003-11-24 | 2010-09-07 | Northwest Biotherapeutics, Inc. | Tangential flow filtration devices and methods for stem cell enrichment |
| US20050197496A1 (en) * | 2004-03-04 | 2005-09-08 | Gtc Biotherapeutics, Inc. | Methods of protein fractionation using high performance tangential flow filtration |
| DK1786273T3 (en) * | 2004-08-20 | 2019-02-18 | Prometic Biosciences Ltd | SEQUENTIAL PROTEIN INSULATION AND PURIFICATION PLANS WITH AFFINITY CHROMATOGRAPHY |
| CN102741280B (zh) * | 2009-10-30 | 2015-12-02 | 诺维信生物制药丹麦公司 | 白蛋白变体 |
| WO2012174472A1 (en) * | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| EA028343B1 (ru) * | 2011-10-10 | 2017-11-30 | Ампио Фармасьютикалз, Инк. | Лечение дегенеративного заболевания сустава |
| PH12014500686A1 (en) * | 2011-10-10 | 2020-12-18 | Ampio Pharmaceuticals Inc | Implantable medical devices with increased immune tolerance, and methods for making and implanting |
| MX355446B (es) * | 2011-10-28 | 2018-04-18 | Ampio Pharmaceuticals Inc | Tratamiento de rinitis. |
-
2014
- 2014-02-03 EA EA201500783A patent/EA030414B1/ru not_active IP Right Cessation
- 2014-02-03 SG SG10201706213RA patent/SG10201706213RA/en unknown
- 2014-02-03 EP EP14745933.3A patent/EP2950811A4/en not_active Withdrawn
- 2014-02-03 MX MX2015009908A patent/MX2015009908A/es unknown
- 2014-02-03 AU AU2014212095A patent/AU2014212095B2/en not_active Ceased
- 2014-02-03 WO PCT/US2014/014478 patent/WO2014121210A1/en not_active Ceased
- 2014-02-03 KR KR1020157023636A patent/KR20150114984A/ko not_active Withdrawn
- 2014-02-03 JP JP2015556207A patent/JP6387019B2/ja not_active Expired - Fee Related
- 2014-02-03 BR BR112015017958A patent/BR112015017958A2/pt not_active IP Right Cessation
- 2014-02-03 US US14/765,018 patent/US20150366932A1/en not_active Abandoned
- 2014-02-03 SG SG11201505715RA patent/SG11201505715RA/en unknown
- 2014-02-03 CA CA2900050A patent/CA2900050A1/en not_active Abandoned
- 2014-02-03 CN CN201480015923.2A patent/CN105188737A/zh active Pending
- 2014-02-03 HK HK16102846.4A patent/HK1214772A1/zh unknown
-
2015
- 2015-07-23 IL IL240125A patent/IL240125A0/en unknown
- 2015-07-31 PH PH12015501705A patent/PH12015501705A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| SG11201505715RA (en) | 2015-08-28 |
| MX2015009908A (es) | 2015-09-24 |
| CN105188737A (zh) | 2015-12-23 |
| CA2900050A1 (en) | 2014-08-07 |
| EP2950811A1 (en) | 2015-12-09 |
| US20150366932A1 (en) | 2015-12-24 |
| WO2014121210A1 (en) | 2014-08-07 |
| AU2014212095B2 (en) | 2018-07-26 |
| BR112015017958A2 (pt) | 2017-07-11 |
| EP2950811A4 (en) | 2016-06-08 |
| AU2014212095A1 (en) | 2015-09-10 |
| EA030414B1 (ru) | 2018-08-31 |
| JP6387019B2 (ja) | 2018-09-05 |
| HK1214772A1 (zh) | 2016-08-05 |
| JP2016511238A (ja) | 2016-04-14 |
| SG10201706213RA (en) | 2017-09-28 |
| EA201500783A1 (ru) | 2016-05-31 |
| IL240125A0 (en) | 2015-09-24 |
| KR20150114984A (ko) | 2015-10-13 |
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