CA2891010C - Actrii receptor polypeptides, methods and compositions - Google Patents

Actrii receptor polypeptides, methods and compositions Download PDF

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Publication number
CA2891010C
CA2891010C CA2891010A CA2891010A CA2891010C CA 2891010 C CA2891010 C CA 2891010C CA 2891010 A CA2891010 A CA 2891010A CA 2891010 A CA2891010 A CA 2891010A CA 2891010 C CA2891010 C CA 2891010C
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Canada
Prior art keywords
actrii
use according
patient
antibody
muscular dystrophy
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Expired - Lifetime
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CA2891010A
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English (en)
French (fr)
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CA2891010A1 (en
Inventor
John Knopf
Jasbir Seehra
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Acceleron Pharma Inc
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Acceleron Pharma Inc
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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y207/00—Transferases transferring phosphorus-containing groups (2.7)
    • C12Y207/11—Protein-serine/threonine kinases (2.7.11)
    • C12Y207/1103—Receptor protein serine/threonine kinase (2.7.11.30)

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CA2891010A 2004-07-23 2005-07-25 Actrii receptor polypeptides, methods and compositions Expired - Lifetime CA2891010C (en)

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US59076504P 2004-07-23 2004-07-23
US60/590,765 2004-07-23
CA2574777A CA2574777C (en) 2004-07-23 2005-07-25 Actrii receptor polypeptides, methods and compositions

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CA2891010A1 CA2891010A1 (en) 2006-02-02
CA2891010C true CA2891010C (en) 2022-09-20

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US (5) US7709605B2 (cg-RX-API-DMAC7.html)
EP (5) EP1771470B1 (cg-RX-API-DMAC7.html)
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