IL132922A0 - The use of a bone morphogenetic protein (bmp) receptor complex for screening - Google Patents

The use of a bone morphogenetic protein (bmp) receptor complex for screening

Info

Publication number
IL132922A0
IL132922A0 IL13292298A IL13292298A IL132922A0 IL 132922 A0 IL132922 A0 IL 132922A0 IL 13292298 A IL13292298 A IL 13292298A IL 13292298 A IL13292298 A IL 13292298A IL 132922 A0 IL132922 A0 IL 132922A0
Authority
IL
Israel
Prior art keywords
bmp
screening
receptor complex
bone morphogenetic
morphogenetic protein
Prior art date
Application number
IL13292298A
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of IL132922A0 publication Critical patent/IL132922A0/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/71—Assays involving receptors, cell surface antigens or cell surface determinants for growth factors; for growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL13292298A 1997-05-16 1998-05-13 The use of a bone morphogenetic protein (bmp) receptor complex for screening IL132922A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4676897P 1997-05-16 1997-05-16
PCT/US1998/009519 WO1998052038A1 (en) 1997-05-16 1998-05-13 The use of a bone morphogenetic protein (bmp) receptor complex for screening

Publications (1)

Publication Number Publication Date
IL132922A0 true IL132922A0 (en) 2001-03-19

Family

ID=21945289

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13292298A IL132922A0 (en) 1997-05-16 1998-05-13 The use of a bone morphogenetic protein (bmp) receptor complex for screening

Country Status (6)

Country Link
EP (1) EP0981745A1 (en)
JP (1) JP2002510198A (en)
AU (1) AU7478298A (en)
CA (1) CA2290755A1 (en)
IL (1) IL132922A0 (en)
WO (1) WO1998052038A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6656475B1 (en) * 1997-08-01 2003-12-02 The Johns Hopkins University School Of Medicine Growth differentiation factor receptors, agonists and antagonists thereof, and methods of using same
US6891082B2 (en) * 1997-08-01 2005-05-10 The Johns Hopkins University School Of Medicine Transgenic non-human animals expressing a truncated activintype II receptor
ES2426005T3 (en) * 2004-07-23 2013-10-18 Acceleron Pharma Inc. ACTRII receptor polypeptides, procedures and compositions
AU2015200950B2 (en) * 2004-07-23 2017-04-27 Acceleron Pharma Inc. ActRII receptor polypeptides, methods and compositions
JP5638961B2 (en) * 2008-03-13 2014-12-10 ザ ジェネラル ホスピタル コーポレイション Inhibitors of BMP signaling pathway
EP2970311A4 (en) 2013-03-14 2016-11-23 Brigham & Womens Hospital Bmp inhibitors and methods of use thereof
WO2016011019A1 (en) 2014-07-15 2016-01-21 The Brigham And Women's Hospital, Inc. Compositions and methods for inhibiting bmp
US11440949B2 (en) 2016-10-05 2022-09-13 Acceleron Pharma Inc. TGF-beta superfamily type I and type II receptor heteromultimers and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248554B1 (en) * 1993-11-24 2001-06-19 The Procter & Gamble Company DNA sequence coding for a BMP receptor
US6210899B1 (en) * 1994-11-04 2001-04-03 The Procter & Gamble Company Use of a BMP protein receptor complex for screening bone metabolism actives and cells co-transfected with a type II BMP receptor and type I BMP receptor
US6306622B1 (en) * 1994-11-04 2001-10-23 The Procter & Gamble Co. cDNA encoding a BMP type II receptor

Also Published As

Publication number Publication date
WO1998052038A1 (en) 1998-11-19
EP0981745A1 (en) 2000-03-01
AU7478298A (en) 1998-12-08
JP2002510198A (en) 2002-04-02
CA2290755A1 (en) 1998-11-19

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