CA2878587A1 - Immunoglobulin constructs comprising selective pairing of the light and heavy chains - Google Patents
Immunoglobulin constructs comprising selective pairing of the light and heavy chains Download PDFInfo
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- CA2878587A1 CA2878587A1 CA2878587A CA2878587A CA2878587A1 CA 2878587 A1 CA2878587 A1 CA 2878587A1 CA 2878587 A CA2878587 A CA 2878587A CA 2878587 A CA2878587 A CA 2878587A CA 2878587 A1 CA2878587 A1 CA 2878587A1
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- polypeptide
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- immunoglobulin construct
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Applications Claiming Priority (5)
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| US201261674820P | 2012-07-23 | 2012-07-23 | |
| US61/674,820 | 2012-07-23 | ||
| US201361857652P | 2013-07-23 | 2013-07-23 | |
| PCT/US2013/051747 WO2014018572A2 (en) | 2012-07-23 | 2013-07-23 | Immunoglobulin constructs comprising selective pairing of the light and heavy chains |
| US61/857,652 | 2013-07-23 |
Publications (1)
| Publication Number | Publication Date |
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| CA2878587A1 true CA2878587A1 (en) | 2014-01-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CA2878587A Abandoned CA2878587A1 (en) | 2012-07-23 | 2013-07-23 | Immunoglobulin constructs comprising selective pairing of the light and heavy chains |
Country Status (7)
| Country | Link |
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| US (1) | US20140072581A1 (forum.php) |
| JP (1) | JP2015531751A (forum.php) |
| CN (1) | CN104640561A (forum.php) |
| AU (1) | AU2013293092A1 (forum.php) |
| CA (1) | CA2878587A1 (forum.php) |
| IN (1) | IN2015DN01299A (forum.php) |
| WO (1) | WO2014018572A2 (forum.php) |
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| US9023352B2 (en) | 2007-02-20 | 2015-05-05 | Tufts University | Methods, compositions and kits for treating a subject using a recombinant heteromultimeric neutralizing binding protein |
| US9493578B2 (en) | 2009-09-02 | 2016-11-15 | Xencor, Inc. | Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens |
| DK3029066T3 (da) | 2010-07-29 | 2019-05-20 | Xencor Inc | Antistoffer med modificerede isoelektriske punkter |
| HUE047228T2 (hu) | 2010-11-05 | 2020-04-28 | Zymeworks Inc | Stabil heterodimer antitest-kialakítás az FC doménben mutációval |
| CA2828811C (en) | 2011-03-03 | 2021-09-21 | Zymeworks Inc. | Multivalent heteromultimer scaffold design and constructs |
| US10851178B2 (en) | 2011-10-10 | 2020-12-01 | Xencor, Inc. | Heterodimeric human IgG1 polypeptides with isoelectric point modifications |
| EP2773671B1 (en) | 2011-11-04 | 2021-09-15 | Zymeworks Inc. | Stable heterodimeric antibody design with mutations in the fc domain |
| US9499634B2 (en) | 2012-06-25 | 2016-11-22 | Zymeworks Inc. | Process and methods for efficient manufacturing of highly pure asymmetric antibodies in mammalian cells |
| AU2013289881B2 (en) | 2012-07-13 | 2018-01-18 | Zymeworks Bc Inc. | Multivalent heteromultimer scaffold design and constructs |
| EP2914634B1 (en) * | 2012-11-02 | 2017-12-06 | Zymeworks Inc. | Crystal structures of heterodimeric fc domains |
| US9914785B2 (en) | 2012-11-28 | 2018-03-13 | Zymeworks Inc. | Engineered immunoglobulin heavy chain-light chain pairs and uses thereof |
| US11053316B2 (en) | 2013-01-14 | 2021-07-06 | Xencor, Inc. | Optimized antibody variable regions |
| CA3211863A1 (en) | 2013-01-14 | 2014-07-17 | Xencor, Inc. | Novel heterodimeric proteins |
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