CA2878481A1 - Method for preparing substituted triazolopyridines - Google Patents
Method for preparing substituted triazolopyridines Download PDFInfo
- Publication number
- CA2878481A1 CA2878481A1 CA2878481A CA2878481A CA2878481A1 CA 2878481 A1 CA2878481 A1 CA 2878481A1 CA 2878481 A CA2878481 A CA 2878481A CA 2878481 A CA2878481 A CA 2878481A CA 2878481 A1 CA2878481 A1 CA 2878481A1
- Authority
- CA
- Canada
- Prior art keywords
- amino
- phenyl
- pyridin
- triazolo
- fluorophenyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 0 CCN(CC)C(c(cc1)cc(OCC(F)(F)F)c1Nc1n[n](cc(*)cc2)c2n1)=O Chemical compound CCN(CC)C(c(cc1)cc(OCC(F)(F)F)c1Nc1n[n](cc(*)cc2)c2n1)=O 0.000 description 24
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12175640.7 | 2012-07-10 | ||
| EP12175640 | 2012-07-10 | ||
| EP12185590 | 2012-09-24 | ||
| EP12185590.2 | 2012-09-24 | ||
| EP13170585.7 | 2013-06-05 | ||
| EP13170585 | 2013-06-05 | ||
| PCT/EP2013/064017 WO2014009219A1 (en) | 2012-07-10 | 2013-07-03 | Method for preparing substituted triazolopyridines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2878481A1 true CA2878481A1 (en) | 2014-01-16 |
Family
ID=48793197
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2878481A Abandoned CA2878481A1 (en) | 2012-07-10 | 2013-07-03 | Method for preparing substituted triazolopyridines |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US9388177B2 (en:Method) |
| EP (1) | EP2872506A1 (en:Method) |
| JP (1) | JP6238979B2 (en:Method) |
| KR (1) | KR20150040845A (en:Method) |
| CN (1) | CN104603136B (en:Method) |
| AP (1) | AP3778A (en:Method) |
| AU (1) | AU2013289381A1 (en:Method) |
| BR (1) | BR112015000308A2 (en:Method) |
| CA (1) | CA2878481A1 (en:Method) |
| CL (1) | CL2015000038A1 (en:Method) |
| CO (1) | CO7160002A2 (en:Method) |
| CR (1) | CR20150006A (en:Method) |
| DO (1) | DOP2015000007A (en:Method) |
| EA (1) | EA027544B1 (en:Method) |
| HK (1) | HK1206731A1 (en:Method) |
| IL (1) | IL236265A (en:Method) |
| IN (1) | IN2015DN00085A (en:Method) |
| MX (1) | MX2015000348A (en:Method) |
| NZ (1) | NZ703020A (en:Method) |
| PE (1) | PE20150354A1 (en:Method) |
| PH (1) | PH12015500061A1 (en:Method) |
| SG (1) | SG11201408419QA (en:Method) |
| TN (1) | TN2015000008A1 (en:Method) |
| WO (1) | WO2014009219A1 (en:Method) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2914521A1 (en) * | 2013-06-07 | 2014-12-11 | Bayer Pharma Aktiengesellschaft | Substituted triazolopyridines having activity as mps-1 inhibitors |
| PL3008062T3 (pl) * | 2013-06-11 | 2017-08-31 | Bayer Pharma Aktiengesellschaft | Pochodne proleki podstawionych triazolopirydyn |
| EP3007692A1 (en) | 2013-06-11 | 2016-04-20 | Bayer Pharma Aktiengesellschaft | Combinations for the treatment of cancer comprising a mps-1 kinase inhibitor and a mitotic inhibitor |
| KR102720422B1 (ko) | 2015-04-17 | 2024-10-22 | 크로스파이어 온콜로지 홀딩 비.브이. | Ttk 억제제 화학요법을 위한 예후 바이오마커 |
| TW201800408A (zh) | 2016-06-15 | 2018-01-01 | 拜耳製藥公司 | Mps-1抑制劑 |
Family Cites Families (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2003030937A1 (ja) * | 2001-10-05 | 2005-01-20 | 小野薬品工業株式会社 | ミトコンドリアルベンゾジアゼピン受容体アンタゴニストからなるストレス疾患の治療剤 |
| JP2007537296A (ja) * | 2004-05-14 | 2007-12-20 | アボット・ラボラトリーズ | 治療薬としてのキナーゼ阻害薬 |
| UA89503C2 (uk) * | 2004-09-13 | 2010-02-10 | Х. Луннбек А/С | Заміщені похідні аніліну |
| CA2582482A1 (en) * | 2004-10-07 | 2006-04-13 | Warner-Lambert Company Llc | Triazolopyridine derivatives as antibacterial agents |
| US20060194823A1 (en) * | 2004-12-22 | 2006-08-31 | Georg Kettschau | Sulfonamido-macrocycles as Tie2 inhibitors and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof |
| TW200808802A (en) * | 2006-06-06 | 2008-02-16 | Schering Corp | Imidazopyrazines as protein kinase inhibitors |
| EP1870416A1 (en) * | 2006-06-21 | 2007-12-26 | Bayer Schering Pharma Aktiengesellschaft | Sulphonamido-macrocycles as tie2 inhibitors |
| US8883820B2 (en) | 2006-08-30 | 2014-11-11 | Cellzome Ltd. | Triazole derivatives as kinase inhibitors |
| JO3598B1 (ar) * | 2006-10-10 | 2020-07-05 | Infinity Discovery Inc | الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني |
| WO2009010530A1 (en) | 2007-07-18 | 2009-01-22 | Novartis Ag | Bicyclic heteroaryl compounds and their use as kinase inhibitors |
| NZ584138A (en) | 2007-08-23 | 2011-10-28 | Astrazeneca Ab | 2-anilinopurin-8-ones as inhibitors of ttk/mps1 for the treatment of proliferative disorders |
| MX2010002312A (es) | 2007-08-31 | 2010-03-18 | Merck Serono Sa | Compuestos de triazolopiridina y su uso como inhibidores de cinasa reguladora de señal de apoptosis. |
| GB0719803D0 (en) | 2007-10-10 | 2007-11-21 | Cancer Rec Tech Ltd | Therapeutic compounds and their use |
| GB0724342D0 (en) * | 2007-12-13 | 2008-01-30 | Prolysis Ltd | Anitbacterial compositions |
| US8530689B2 (en) * | 2008-05-05 | 2013-09-10 | The Trustees Of The University Of Pennsylvania | Processes for the preparation of biphenyl compounds |
| WO2009155527A2 (en) * | 2008-06-19 | 2009-12-23 | Progenics Pharmaceuticals, Inc. | Phosphatidylinositol 3 kinase inhibitors |
| NZ594508A (en) | 2009-02-13 | 2013-12-20 | Fovea Pharmaceuticals | [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors |
| CA2760077A1 (en) | 2009-04-29 | 2010-11-04 | Marcus Koppitz | Substituted imidazoquinoxalines |
| JP5684245B2 (ja) * | 2009-06-05 | 2015-03-11 | セファロン、インク． | １，２，４−トリアゾロ［１，５ａ］ピリジン誘導体の調製および使用 |
| WO2010141360A1 (en) * | 2009-06-05 | 2010-12-09 | Merck Sharp & Dohme Corp. | Biaryl benzotriazole derivatives |
| EP2473498A1 (en) | 2009-09-04 | 2012-07-11 | Bayer Pharma Aktiengesellschaft | Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors |
| EP2343297A1 (en) * | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Triazolopyridines |
| EP2343295A1 (en) * | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Triazolopyridine derivates |
| EP2343294A1 (en) * | 2009-11-30 | 2011-07-13 | Bayer Schering Pharma AG | Substituted triazolopyridines |
| UY33452A (es) * | 2010-06-16 | 2012-01-31 | Bayer Schering Pharma Ag | Triazolopiridinas sustituidas |
| WO2012044567A2 (en) * | 2010-09-30 | 2012-04-05 | Merck Sharp & Dohme Corp. | Imidazole derivatives |
| DK2699575T3 (da) * | 2011-04-21 | 2015-06-22 | Bayer Ip Gmbh | Triazolopyridiner |
| WO2012160029A1 (en) * | 2011-05-23 | 2012-11-29 | Bayer Intellectual Property Gmbh | Substituted triazolopyridines |
| UA112096C2 (uk) * | 2011-12-12 | 2016-07-25 | Байєр Інтеллектуал Проперті Гмбх | Заміщені триазолопіридини та їх застосування як інгібіторів ttk |
-
2013
- 2013-07-03 SG SG11201408419QA patent/SG11201408419QA/en unknown
- 2013-07-03 US US14/414,164 patent/US9388177B2/en not_active Expired - Fee Related
- 2013-07-03 EP EP13737181.1A patent/EP2872506A1/en not_active Withdrawn
- 2013-07-03 IN IN85DEN2015 patent/IN2015DN00085A/en unknown
- 2013-07-03 AP AP2014008177A patent/AP3778A/en active
- 2013-07-03 EA EA201590116A patent/EA027544B1/ru not_active IP Right Cessation
- 2013-07-03 NZ NZ703020A patent/NZ703020A/en not_active IP Right Cessation
- 2013-07-03 KR KR20157000338A patent/KR20150040845A/ko not_active Withdrawn
- 2013-07-03 WO PCT/EP2013/064017 patent/WO2014009219A1/en active Application Filing
- 2013-07-03 BR BR112015000308A patent/BR112015000308A2/pt not_active IP Right Cessation
- 2013-07-03 JP JP2015520907A patent/JP6238979B2/ja not_active Expired - Fee Related
- 2013-07-03 CA CA2878481A patent/CA2878481A1/en not_active Abandoned
- 2013-07-03 PE PE2015000017A patent/PE20150354A1/es not_active Application Discontinuation
- 2013-07-03 CN CN201380045913.9A patent/CN104603136B/zh not_active Expired - Fee Related
- 2013-07-03 MX MX2015000348A patent/MX2015000348A/es unknown
- 2013-07-03 AU AU2013289381A patent/AU2013289381A1/en not_active Abandoned
- 2013-07-03 HK HK15107242.4A patent/HK1206731A1/xx unknown
-
2014
- 2014-12-15 IL IL236265A patent/IL236265A/en not_active IP Right Cessation
-
2015
- 2015-01-07 TN TNP2015000008A patent/TN2015000008A1/fr unknown
- 2015-01-08 CL CL2015000038A patent/CL2015000038A1/es unknown
- 2015-01-09 CR CR20150006A patent/CR20150006A/es unknown
- 2015-01-09 DO DO2015000007A patent/DOP2015000007A/es unknown
- 2015-01-09 CO CO15004251A patent/CO7160002A2/es unknown
- 2015-01-09 PH PH12015500061A patent/PH12015500061A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DOP2015000007A (es) | 2015-02-15 |
| CL2015000038A1 (es) | 2015-03-13 |
| EA201590116A1 (ru) | 2015-07-30 |
| AU2013289381A1 (en) | 2015-01-22 |
| IL236265A0 (en) | 2015-02-26 |
| PE20150354A1 (es) | 2015-03-21 |
| CN104603136A (zh) | 2015-05-06 |
| WO2014009219A1 (en) | 2014-01-16 |
| CR20150006A (es) | 2015-02-16 |
| NZ703020A (en) | 2017-08-25 |
| JP6238979B2 (ja) | 2017-11-29 |
| BR112015000308A2 (pt) | 2017-06-27 |
| US9388177B2 (en) | 2016-07-12 |
| CN104603136B (zh) | 2017-06-27 |
| JP2015523372A (ja) | 2015-08-13 |
| IN2015DN00085A (en:Method) | 2015-05-29 |
| EA027544B1 (ru) | 2017-08-31 |
| MX2015000348A (es) | 2015-04-14 |
| AP2014008177A0 (en) | 2014-12-31 |
| SG11201408419QA (en) | 2015-01-29 |
| IL236265A (en) | 2017-07-31 |
| CO7160002A2 (es) | 2015-01-15 |
| HK1206731A1 (en) | 2016-01-15 |
| EP2872506A1 (en) | 2015-05-20 |
| PH12015500061A1 (en) | 2015-03-02 |
| US20150148542A1 (en) | 2015-05-28 |
| KR20150040845A (ko) | 2015-04-15 |
| TN2015000008A1 (en) | 2016-06-29 |
| AP3778A (en) | 2016-08-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20190703 |