BR112015000308A2 - método para preparo de triazolopiridinas substituídas - Google Patents

método para preparo de triazolopiridinas substituídas

Info

Publication number
BR112015000308A2
BR112015000308A2 BR112015000308A BR112015000308A BR112015000308A2 BR 112015000308 A2 BR112015000308 A2 BR 112015000308A2 BR 112015000308 A BR112015000308 A BR 112015000308A BR 112015000308 A BR112015000308 A BR 112015000308A BR 112015000308 A2 BR112015000308 A2 BR 112015000308A2
Authority
BR
Brazil
Prior art keywords
preparing substituted
triazolopyridines
substituted triazolopyridines
preparing
general formula
Prior art date
Application number
BR112015000308A
Other languages
English (en)
Inventor
Mais Franz-Josef
Schulze Volker
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of BR112015000308A2 publication Critical patent/BR112015000308A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

resumo patente de invenção: "método para preparo de triazolopiridinas substituídas". a presente invenção refere-se a métodos de preparo de compostos de triazolopiridina substituída de fórmula geral (i) (i) conforme descrito e definido aqui, bem como a compostos intermediários úteis no preparo dos ditos grupos compostos.
BR112015000308A 2012-07-10 2013-07-03 método para preparo de triazolopiridinas substituídas BR112015000308A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP12175640 2012-07-10
EP12185590 2012-09-24
EP13170585 2013-06-05
PCT/EP2013/064017 WO2014009219A1 (en) 2012-07-10 2013-07-03 Method for preparing substituted triazolopyridines

Publications (1)

Publication Number Publication Date
BR112015000308A2 true BR112015000308A2 (pt) 2017-06-27

Family

ID=48793197

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015000308A BR112015000308A2 (pt) 2012-07-10 2013-07-03 método para preparo de triazolopiridinas substituídas

Country Status (24)

Country Link
US (1) US9388177B2 (pt)
EP (1) EP2872506A1 (pt)
JP (1) JP6238979B2 (pt)
KR (1) KR20150040845A (pt)
CN (1) CN104603136B (pt)
AP (1) AP3778A (pt)
AU (1) AU2013289381A1 (pt)
BR (1) BR112015000308A2 (pt)
CA (1) CA2878481A1 (pt)
CL (1) CL2015000038A1 (pt)
CO (1) CO7160002A2 (pt)
CR (1) CR20150006A (pt)
DO (1) DOP2015000007A (pt)
EA (1) EA027544B1 (pt)
HK (1) HK1206731A1 (pt)
IL (1) IL236265A (pt)
IN (1) IN2015DN00085A (pt)
MX (1) MX2015000348A (pt)
NZ (1) NZ703020A (pt)
PE (1) PE20150354A1 (pt)
PH (1) PH12015500061A1 (pt)
SG (1) SG11201408419QA (pt)
TN (1) TN2015000008A1 (pt)
WO (1) WO2014009219A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014195276A1 (en) * 2013-06-07 2014-12-11 Bayer Pharma Aktiengesellschaft Substituted triazolopyridines having activity as mps-1 inhibitors
AP2015008898A0 (en) * 2013-06-11 2015-12-31 Bayer Pharma AG Prodrug derivatives of substituted triazolopyridines
CA2914742A1 (en) 2013-06-11 2014-12-18 Bayer Pharma Aktiengesellschaft Handovers with co-operating cells configured to provide coordinated multi-point transmission/reception
FI3283642T3 (fi) 2015-04-17 2024-01-11 Crossfire Oncology Holding B V Prognostisia biomarkkereita ttk-inhibiittorikemoterapiaan
TW201800408A (zh) 2016-06-15 2018-01-01 拜耳製藥公司 Mps-1抑制劑

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2003030937A1 (ja) * 2001-10-05 2005-01-20 小野薬品工業株式会社 ミトコンドリアルベンゾジアゼピン受容体アンタゴニストからなるストレス疾患の治療剤
CA2566158A1 (en) * 2004-05-14 2005-11-24 Abbott Laboratories Kinase inhibitors as therapeutic agents
UA89503C2 (uk) * 2004-09-13 2010-02-10 Х. Луннбек А/С Заміщені похідні аніліну
MX2007004179A (es) * 2004-10-07 2007-06-07 Warner Lambert Co Derivados de triazolpiridina como agentes antibacterianos.
US20060194823A1 (en) * 2004-12-22 2006-08-31 Georg Kettschau Sulfonamido-macrocycles as Tie2 inhibitors and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof
JP2009539840A (ja) * 2006-06-06 2009-11-19 シェーリング コーポレイション プロテインキナーゼ阻害剤としてのイミダゾピラジン
EP1870416A1 (en) * 2006-06-21 2007-12-26 Bayer Schering Pharma Aktiengesellschaft Sulphonamido-macrocycles as tie2 inhibitors
US8883820B2 (en) 2006-08-30 2014-11-11 Cellzome Ltd. Triazole derivatives as kinase inhibitors
JO3598B1 (ar) * 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
JP2010533680A (ja) 2007-07-18 2010-10-28 ノバルティス アーゲー 二環ヘテロアリール化合物およびそれらのキナーゼ阻害剤としての使用
CN103298814A (zh) 2007-08-23 2013-09-11 阿斯利康(瑞典)有限公司 作为治疗增殖性疾病的ttk/mps1抑制剂的2-苯胺基嘌呤-8-酮
JP2010536917A (ja) 2007-08-31 2010-12-02 メルク セローノ ソシエテ アノニム トリアゾロピリジン化合物と、ａｓｋ阻害剤としてのその化合物の利用法
GB0719803D0 (en) 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
GB0724342D0 (en) * 2007-12-13 2008-01-30 Prolysis Ltd Anitbacterial compositions
US8530689B2 (en) * 2008-05-05 2013-09-10 The Trustees Of The University Of Pennsylvania Processes for the preparation of biphenyl compounds
WO2009155527A2 (en) * 2008-06-19 2009-12-23 Progenics Pharmaceuticals, Inc. Phosphatidylinositol 3 kinase inhibitors
NZ594508A (en) 2009-02-13 2013-12-20 Fovea Pharmaceuticals [1, 2, 4] triazolo [1, 5 -a] pyridines as kinase inhibitors
WO2010124826A1 (en) 2009-04-29 2010-11-04 Bayer Schering Pharma Aktiengesellschaft Substituted imidazoquinoxalines
BRPI1009637A2 (pt) * 2009-06-05 2019-04-30 Cephalon, Inc composto, composição e uso de um composto
WO2010141360A1 (en) * 2009-06-05 2010-12-09 Merck Sharp & Dohme Corp. Biaryl benzotriazole derivatives
CN102596932A (zh) 2009-09-04 2012-07-18 拜耳医药股份有限公司 作为酪氨酸苏氨酸激酶抑制剂的取代氨基喹喔啉
EP2343297A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridines
EP2343294A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Substituted triazolopyridines
EP2343295A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridine derivates
UY33452A (es) * 2010-06-16 2012-01-31 Bayer Schering Pharma Ag Triazolopiridinas sustituidas
WO2012044567A2 (en) * 2010-09-30 2012-04-05 Merck Sharp & Dohme Corp. Imidazole derivatives
AP3491A (en) * 2011-04-21 2015-12-31 Bayer Ip Gmbh Triazolopyridines
WO2012160029A1 (en) * 2011-05-23 2012-11-29 Bayer Intellectual Property Gmbh Substituted triazolopyridines
UA112096C2 (uk) * 2011-12-12 2016-07-25 Байєр Інтеллектуал Проперті Гмбх Заміщені триазолопіридини та їх застосування як інгібіторів ttk

Also Published As

Publication number Publication date
IN2015DN00085A (pt) 2015-05-29
DOP2015000007A (es) 2015-02-15
EP2872506A1 (en) 2015-05-20
KR20150040845A (ko) 2015-04-15
MX2015000348A (es) 2015-04-14
CR20150006A (es) 2015-02-16
TN2015000008A1 (en) 2016-06-29
CL2015000038A1 (es) 2015-03-13
JP6238979B2 (ja) 2017-11-29
AU2013289381A1 (en) 2015-01-22
AP3778A (en) 2016-08-31
HK1206731A1 (en) 2016-01-15
IL236265A (en) 2017-07-31
CO7160002A2 (es) 2015-01-15
JP2015523372A (ja) 2015-08-13
EA027544B1 (ru) 2017-08-31
WO2014009219A1 (en) 2014-01-16
SG11201408419QA (en) 2015-01-29
US20150148542A1 (en) 2015-05-28
IL236265A0 (en) 2015-02-26
CN104603136B (zh) 2017-06-27
CN104603136A (zh) 2015-05-06
AP2014008177A0 (en) 2014-12-31
US9388177B2 (en) 2016-07-12
PE20150354A1 (es) 2015-03-21
NZ703020A (en) 2017-08-25
CA2878481A1 (en) 2014-01-16
PH12015500061A1 (en) 2015-03-02
EA201590116A1 (ru) 2015-07-30

Similar Documents

Publication Publication Date Title
CY1116987T1 (el) Συμπυκνωμενα ιμιδαζολυλιμιδαζολια ως αντιϊικες ενωσεις
EA201491672A1 (ru) Гетероциклильные соединения как ингибиторы mek
CR20150370A (es) Compuestos antivirales
CO6771439A2 (es) Inhibidores de benzodioxano de la producción de leucotrieno
EA201301181A1 (ru) Триазолопиридины
EA201491149A1 (ru) Пиразолопиридиновые производные, способы их получения и их терапевтическое применение
EA201491028A1 (ru) Способ получения замещенных 5-фтор-1н-пиразолопиридинов
CO7200270A2 (es) Azaindolcarboxamidas y azaindoltiocarboxamidas como insecticidas y acaricidas
EA201491195A1 (ru) Способ получения композиции, содержащей галактоолигосахариды
CY1118079T1 (el) Μεθοδος παρασκευης του αλατος l-αργινινικης περινδοπριλης
BR112015000308A2 (pt) método para preparo de triazolopiridinas substituídas
ES2421956A1 (es) Nueva forma cristalina de sulfato de sitagliptina
CA2922375C (en) Alpha-tea salt forms: compositions and uses for treating disease
WO2015023508A8 (en) Methods for improving asthma symptoms using benralizumab
EA201590656A1 (ru) Азаиндолины
EA201491581A1 (ru) Везикулярные композиции
EA201391586A1 (ru) ИНГИБИТОРЫ 17α-ГИДРОКСИЛАЗЫ/C-ЛИАЗЫ
BR112013026868A2 (pt) intermediário para a síntese de caspofungina e método para o seu preparo
EA201590594A1 (ru) Макролидные производные, их получение и их терапевтическое использование
UA110822C2 (uk) Піперидинілмонокарбонові кислоти як агоністи s1p1-рецепторів
PH12015502703A1 (en) Pharmaceutical compositions
ITMI20132055A1 (it) Iniettore, nonche' procedimento atto a pilotare o regolare un iniettore
TR201910829T4 (tr) Piripiropen bileşiği hazırlama metodu.
TN2013000426A1 (en) Triazolopyridines
CU24258B1 (es) Sales de 3-3-carboxi-n-etil-n,n-dimetilpropan-1-aminio útiles en el tratamiento de enfermedades cardiovasculares

Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO ARQUIVAMENTO PUBLICADO NA RPI 2521 DE 30/04/2019.