BR112015000308A2 - método para preparo de triazolopiridinas substituídas - Google Patents

método para preparo de triazolopiridinas substituídas

Info

Publication number
BR112015000308A2
BR112015000308A2 BR112015000308A BR112015000308A BR112015000308A2 BR 112015000308 A2 BR112015000308 A2 BR 112015000308A2 BR 112015000308 A BR112015000308 A BR 112015000308A BR 112015000308 A BR112015000308 A BR 112015000308A BR 112015000308 A2 BR112015000308 A2 BR 112015000308A2
Authority
BR
Brazil
Prior art keywords
preparing substituted
triazolopyridines
substituted triazolopyridines
preparing
general formula
Prior art date
Application number
BR112015000308A
Other languages
English (en)
Inventor
Mais Franz-Josef
Schulze Volker
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of BR112015000308A2 publication Critical patent/BR112015000308A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

resumo patente de invenção: "método para preparo de triazolopiridinas substituídas". a presente invenção refere-se a métodos de preparo de compostos de triazolopiridina substituída de fórmula geral (i) (i) conforme descrito e definido aqui, bem como a compostos intermediários úteis no preparo dos ditos grupos compostos.
BR112015000308A 2012-07-10 2013-07-03 método para preparo de triazolopiridinas substituídas BR112015000308A2 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP12175640 2012-07-10
EP12185590 2012-09-24
EP13170585 2013-06-05
PCT/EP2013/064017 WO2014009219A1 (en) 2012-07-10 2013-07-03 Method for preparing substituted triazolopyridines

Publications (1)

Publication Number Publication Date
BR112015000308A2 true BR112015000308A2 (pt) 2017-06-27

Family

ID=48793197

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015000308A BR112015000308A2 (pt) 2012-07-10 2013-07-03 método para preparo de triazolopiridinas substituídas

Country Status (24)

Country Link
US (1) US9388177B2 (pt)
EP (1) EP2872506A1 (pt)
JP (1) JP6238979B2 (pt)
KR (1) KR20150040845A (pt)
CN (1) CN104603136B (pt)
AP (1) AP3778A (pt)
AU (1) AU2013289381A1 (pt)
BR (1) BR112015000308A2 (pt)
CA (1) CA2878481A1 (pt)
CL (1) CL2015000038A1 (pt)
CO (1) CO7160002A2 (pt)
CR (1) CR20150006A (pt)
DO (1) DOP2015000007A (pt)
EA (1) EA027544B1 (pt)
HK (1) HK1206731A1 (pt)
IL (1) IL236265A (pt)
IN (1) IN2015DN00085A (pt)
MX (1) MX2015000348A (pt)
NZ (1) NZ703020A (pt)
PE (1) PE20150354A1 (pt)
PH (1) PH12015500061A1 (pt)
SG (1) SG11201408419QA (pt)
TN (1) TN2015000008A1 (pt)
WO (1) WO2014009219A1 (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014195276A1 (en) * 2013-06-07 2014-12-11 Bayer Pharma Aktiengesellschaft Substituted triazolopyridines having activity as mps-1 inhibitors
EP3008062B1 (en) * 2013-06-11 2017-04-05 Bayer Pharma Aktiengesellschaft Prodrug derivatives of substituted triazolopyridines
SG11201509350RA (en) 2013-06-11 2015-12-30 Bayer Pharma AG Combinations for the treatment of cancer comprising a mps-1 kinase inhibitor and a mitotic inhibitor
ES2966392T3 (es) 2015-04-17 2024-04-22 Crossfire Oncology Holding B V Biomarcadores pronósticos para quimioterapia inhibidora de TTK
TW201800408A (zh) 2016-06-15 2018-01-01 拜耳製藥公司 Mps-1抑制劑

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US20050009812A1 (en) * 2001-10-05 2005-01-13 Takuya Seko Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists
WO2005110410A2 (en) * 2004-05-14 2005-11-24 Abbott Laboratories Kinase inhibitors as therapeutic agents
UA89503C2 (uk) * 2004-09-13 2010-02-10 Х. Луннбек А/С Заміщені похідні аніліну
EP1799680A2 (en) * 2004-10-07 2007-06-27 Warner-Lambert Company LLC Triazolopyridine derivatives as antibacterial agents
US20060194823A1 (en) * 2004-12-22 2006-08-31 Georg Kettschau Sulfonamido-macrocycles as Tie2 inhibitors and the salts thereof, a pharmaceutical composition comprising these compounds, the method of preparing and the use thereof
AR061229A1 (es) * 2006-06-06 2008-08-13 Schering Corp Imidazopirazinas como inhibidores de la proteina quinasa
EP1870416A1 (en) * 2006-06-21 2007-12-26 Bayer Schering Pharma Aktiengesellschaft Sulphonamido-macrocycles as tie2 inhibitors
WO2008025821A1 (en) 2006-08-30 2008-03-06 Cellzome Limited Triazole derivatives as kinase inhibitors
JO3598B1 (ar) * 2006-10-10 2020-07-05 Infinity Discovery Inc الاحماض والاسترات البورونية كمثبطات اميد هيدروليز الحامض الدهني
CA2693232A1 (en) 2007-07-18 2009-01-22 Novartis Ag Bicyclic heteroaryl compounds and their use as kinase inhibitors
AU2008290330A1 (en) 2007-08-23 2009-02-26 Astrazeneca Ab 2-anilinopurin-8-ones as inhibitors of TTK/Mps1 for the treatment of proliferative disorders
CN101878212A (zh) 2007-08-31 2010-11-03 默克雪兰诺有限公司 三唑并吡啶化合物及其作为ask抑制剂的用途
GB0719803D0 (en) 2007-10-10 2007-11-21 Cancer Rec Tech Ltd Therapeutic compounds and their use
GB0724342D0 (en) * 2007-12-13 2008-01-30 Prolysis Ltd Anitbacterial compositions
US8530689B2 (en) * 2008-05-05 2013-09-10 The Trustees Of The University Of Pennsylvania Processes for the preparation of biphenyl compounds
EP2303890A4 (en) * 2008-06-19 2012-04-11 Progenics Pharm Inc INHIBITORS OF PHOSPHATIDYLINOSITE-3-KINASE
PE20120110A1 (es) 2009-02-13 2012-02-20 Fovea Pharmaceuticals [1,2,4]triazolo[1,5-a]piridinas como inhibidores de cinasa
JP6168773B2 (ja) 2009-04-29 2017-07-26 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングＢａｙｅｒ Ｉｎｔｅｌｌｅｃｔｕａｌ Ｐｒｏｐｅｒｔｙ ＧｍｂＨ 置換イミダゾキノキサリン
CN102459258B (zh) * 2009-06-05 2015-11-25 赛福伦公司 1,2,4-三唑并[1,5a]吡啶衍生物的制备和用途
WO2010141360A1 (en) * 2009-06-05 2010-12-09 Merck Sharp & Dohme Corp. Biaryl benzotriazole derivatives
US9340528B2 (en) 2009-09-04 2016-05-17 Bayer Pharma Aktiengesellschaft Substituted aminoquinoxalines as tyrosine threonine kinase inhibitors
EP2343294A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Substituted triazolopyridines
EP2343297A1 (en) * 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridines
EP2343295A1 (en) 2009-11-30 2011-07-13 Bayer Schering Pharma AG Triazolopyridine derivates
UY33452A (es) * 2010-06-16 2012-01-31 Bayer Schering Pharma Ag Triazolopiridinas sustituidas
WO2012044567A2 (en) * 2010-09-30 2012-04-05 Merck Sharp & Dohme Corp. Imidazole derivatives
CA2833657A1 (en) * 2011-04-21 2012-10-26 Bayer Intellectual Property Gmbh Triazolopyridines
WO2012160029A1 (en) * 2011-05-23 2012-11-29 Bayer Intellectual Property Gmbh Substituted triazolopyridines
UA112096C2 (uk) * 2011-12-12 2016-07-25 Байєр Інтеллектуал Проперті Гмбх Заміщені триазолопіридини та їх застосування як інгібіторів ttk

Also Published As

Publication number Publication date
KR20150040845A (ko) 2015-04-15
EA201590116A1 (ru) 2015-07-30
CO7160002A2 (es) 2015-01-15
EA027544B1 (ru) 2017-08-31
NZ703020A (en) 2017-08-25
EP2872506A1 (en) 2015-05-20
JP6238979B2 (ja) 2017-11-29
CA2878481A1 (en) 2014-01-16
AP3778A (en) 2016-08-31
CR20150006A (es) 2015-02-16
US9388177B2 (en) 2016-07-12
IL236265A (en) 2017-07-31
DOP2015000007A (es) 2015-02-15
CL2015000038A1 (es) 2015-03-13
PE20150354A1 (es) 2015-03-21
AP2014008177A0 (en) 2014-12-31
PH12015500061A1 (en) 2015-03-02
WO2014009219A1 (en) 2014-01-16
IN2015DN00085A (pt) 2015-05-29
JP2015523372A (ja) 2015-08-13
CN104603136A (zh) 2015-05-06
US20150148542A1 (en) 2015-05-28
TN2015000008A1 (en) 2016-06-29
MX2015000348A (es) 2015-04-14
SG11201408419QA (en) 2015-01-29
AU2013289381A1 (en) 2015-01-22
IL236265A0 (en) 2015-02-26
HK1206731A1 (en) 2016-01-15
CN104603136B (zh) 2017-06-27

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Legal Events

Date Code Title Description
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B06I Publication of requirement cancelled [chapter 6.9 patent gazette]

Free format text: ANULADA A PUBLICACAO CODIGO 6.6.1 NA RPI NO 2462 DE 13/03/2018 POR TER SIDO INDEVIDA.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO ARQUIVAMENTO PUBLICADO NA RPI 2521 DE 30/04/2019.