CA2864956A1 - Lots d'adenovirus recombinants ayant des extremites terminales modifiees - Google Patents

Lots d'adenovirus recombinants ayant des extremites terminales modifiees Download PDF

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Publication number
CA2864956A1
CA2864956A1 CA2864956A CA2864956A CA2864956A1 CA 2864956 A1 CA2864956 A1 CA 2864956A1 CA 2864956 A CA2864956 A CA 2864956A CA 2864956 A CA2864956 A CA 2864956A CA 2864956 A1 CA2864956 A1 CA 2864956A1
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Prior art keywords
adenovirus
recombinant
human
sequence
adv
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CA2864956A
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CA2864956C (fr
Inventor
Jerome H.H.V. Custers
Jort Vellinga
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Janssen Vaccines and Prevention BV
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Crucell Holand BV
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/02—Recovery or purification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10341—Use of virus, viral particle or viral elements as a vector
    • C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/10011—Adenoviridae
    • C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
    • C12N2710/10351—Methods of production or purification of viral material
CA2864956A 2012-03-12 2013-03-11 Lots d'adenovirus recombinants ayant des extremites terminales modifiees Active CA2864956C (fr)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261609678P 2012-03-12 2012-03-12
EP12159009.5 2012-03-12
EP12159009 2012-03-12
US61/609,678 2012-03-12
PCT/EP2013/054846 WO2013135615A1 (fr) 2012-03-12 2013-03-11 Lots d'adénovirus recombinants ayant des extrémités terminales modifiées

Publications (2)

Publication Number Publication Date
CA2864956A1 true CA2864956A1 (fr) 2013-09-19
CA2864956C CA2864956C (fr) 2021-11-09

Family

ID=49160272

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2864956A Active CA2864956C (fr) 2012-03-12 2013-03-11 Lots d'adenovirus recombinants ayant des extremites terminales modifiees

Country Status (17)

Country Link
EP (1) EP2825640B1 (fr)
JP (1) JP5770952B2 (fr)
KR (1) KR102044051B1 (fr)
CN (1) CN104379733B (fr)
AR (1) AR090318A1 (fr)
AU (1) AU2013231423B2 (fr)
CA (1) CA2864956C (fr)
DK (1) DK2825640T3 (fr)
EA (1) EA034284B1 (fr)
ES (1) ES2582504T3 (fr)
HU (1) HUE027839T2 (fr)
NZ (1) NZ628385A (fr)
PL (1) PL2825640T3 (fr)
SG (1) SG11201405228VA (fr)
SI (1) SI2825640T1 (fr)
TW (1) TWI633188B (fr)
WO (1) WO2013135615A1 (fr)

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US10294279B2 (en) 2013-06-17 2019-05-21 Janssen Vaccines & Prevention B.V. Stabilized soluble pre-fusion RSV F polypeptides
BR112017028449A2 (pt) 2015-07-07 2018-09-04 Janssen Vaccines & Prevention Bv polipeptídeos rsv f pré-fusão solúveis estabilizados
BR112017027448A2 (pt) 2015-07-07 2018-09-04 Janssen Vaccines & Prevention Bv vacina contra rsv
GB201513010D0 (en) 2015-07-23 2015-09-09 Glaxosmithkline Biolog Sa Novel formulation
EP4155411A1 (fr) 2016-02-23 2023-03-29 Salk Institute for Biological Studies Expression d'un gène exogene d'un adenovirus therapeutique avec impact minimaire sur la cinetique virale
EP3390428B1 (fr) 2016-02-23 2019-09-25 Salk Institute for Biological Studies Dosage à haut débit pour mesurer la cinétique de réplication d'un adénovirus
SG11201807913XA (en) 2016-04-05 2018-10-30 Janssen Vaccines & Prevention Bv Stabilized soluble pre-fusion rsv f proteins
CA3018139A1 (fr) 2016-04-05 2017-10-12 Janssen Vaccines & Prevention B.V. Vaccin contre le rsv
ES2829272T3 (es) * 2016-05-12 2021-05-31 Janssen Vaccines & Prevention Bv Promotor bidireccional potente y equilibrado
SG11201810078PA (en) 2016-05-30 2018-12-28 Janssen Vaccines & Prevention Bv Stabilized pre-fusion rsv f proteins
US10744196B2 (en) 2016-07-14 2020-08-18 Janssen Vaccines & Prevention B.V. HPV vaccines
AU2017375633C1 (en) 2016-12-12 2023-04-27 Salk Institute For Biological Studies Tumor-targeting synthetic adenoviruses and uses thereof
US11229692B2 (en) 2017-05-17 2022-01-25 Janssen Vaccines & Prevention B.V. Methods and compositions for inducing protective immunity against RSV infection
EP3681533A1 (fr) 2017-09-15 2020-07-22 Janssen Vaccines & Prevention B.V. Procédé d'induction sûre de l'immunité contre le vrs

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Also Published As

Publication number Publication date
KR102044051B1 (ko) 2019-11-12
EP2825640B1 (fr) 2016-04-27
NZ628385A (en) 2016-09-30
JP2015511597A (ja) 2015-04-20
SG11201405228VA (en) 2014-11-27
CA2864956C (fr) 2021-11-09
AR090318A1 (es) 2014-11-05
TW201336993A (zh) 2013-09-16
JP5770952B2 (ja) 2015-08-26
ES2582504T3 (es) 2016-09-13
CN104379733A (zh) 2015-02-25
TWI633188B (zh) 2018-08-21
WO2013135615A1 (fr) 2013-09-19
AU2013231423A1 (en) 2014-08-28
AU2013231423B2 (en) 2018-10-04
DK2825640T3 (en) 2016-08-01
EP2825640A1 (fr) 2015-01-21
PL2825640T3 (pl) 2016-10-31
EA034284B1 (ru) 2020-01-24
HUE027839T2 (en) 2016-11-28
EA201491676A1 (ru) 2014-12-30
SI2825640T1 (sl) 2016-08-31
CN104379733B (zh) 2016-01-20
KR20140139509A (ko) 2014-12-05

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