AR090318A1 - Lotes de adenovirus recombinantes con extremos terminales alterados - Google Patents
Lotes de adenovirus recombinantes con extremos terminales alteradosInfo
- Publication number
- AR090318A1 AR090318A1 ARP130100798A ARP130100798A AR090318A1 AR 090318 A1 AR090318 A1 AR 090318A1 AR P130100798 A ARP130100798 A AR P130100798A AR P130100798 A ARP130100798 A AR P130100798A AR 090318 A1 AR090318 A1 AR 090318A1
- Authority
- AR
- Argentina
- Prior art keywords
- batches
- altered
- adenovirus
- extreme terminals
- adenovirus recombinants
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10351—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Una composición que comprende una pluralidad de partículas de adenovirus recombinantes, que pueden ser adenovirus humanos recombinantes de los serotipos 5, 26, 34, 35, 48, 49 ó 50 o un adenovirus simio recombinante, donde los genomas de esencialmente todas las partículas de adenovirus en dicha composición comprende la secuencia de nucleótidos CTATCTAT como nucleótidos 5 terminales, y métodos para producir dichas composiciones.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12159009 | 2012-03-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
AR090318A1 true AR090318A1 (es) | 2014-11-05 |
Family
ID=49160272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP130100798A AR090318A1 (es) | 2012-03-12 | 2013-03-12 | Lotes de adenovirus recombinantes con extremos terminales alterados |
Country Status (17)
Country | Link |
---|---|
EP (1) | EP2825640B1 (es) |
JP (1) | JP5770952B2 (es) |
KR (1) | KR102044051B1 (es) |
CN (1) | CN104379733B (es) |
AR (1) | AR090318A1 (es) |
AU (1) | AU2013231423B2 (es) |
CA (1) | CA2864956C (es) |
DK (1) | DK2825640T3 (es) |
EA (1) | EA034284B1 (es) |
ES (1) | ES2582504T3 (es) |
HU (1) | HUE027839T2 (es) |
NZ (1) | NZ628385A (es) |
PL (1) | PL2825640T3 (es) |
SG (1) | SG11201405228VA (es) |
SI (1) | SI2825640T1 (es) |
TW (1) | TWI633188B (es) |
WO (1) | WO2013135615A1 (es) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR102089121B1 (ko) | 2013-03-14 | 2020-03-13 | 더 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양살상형 아데노바이러스 조성물 |
MX361774B (es) | 2013-04-25 | 2018-12-17 | Janssen Vaccines & Prevention Bv | Polipéptidos f de prefusión del virus sincicial respiratorio (rsv) solubles y estabilizados. |
PE20160045A1 (es) | 2013-06-17 | 2016-02-18 | Crucell Holland Bv | Polipeptidos f de prefusion del virus sincicial respiratorio (rsv) solubles y estabilizados |
WO2017005844A1 (en) | 2015-07-07 | 2017-01-12 | Janssen Vaccines & Prevention B.V. | Vaccine against rsv |
JP6840718B2 (ja) | 2015-07-07 | 2021-03-10 | ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. | 安定化された可溶性融合前rsv fポリペプチド |
GB201513010D0 (en) | 2015-07-23 | 2015-09-09 | Glaxosmithkline Biolog Sa | Novel formulation |
CN117384961A (zh) | 2016-02-23 | 2024-01-12 | 萨克生物研究学院 | 对病毒动力学影响最小的治疗性腺病毒中的外源基因表达 |
EP3390428B1 (en) * | 2016-02-23 | 2019-09-25 | Salk Institute for Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
BR112018070323A2 (pt) | 2016-04-05 | 2019-01-29 | Janssen Vaccines & Prevention Bv | vacina contra rsv |
AU2017248021B2 (en) | 2016-04-05 | 2021-08-12 | Janssen Vaccines & Prevention B.V. | Stabilized soluble pre-fusion RSV F proteins |
RU2758238C2 (ru) * | 2016-05-12 | 2021-10-26 | Янссен Вэксинс Энд Превеншн Б.В. | Эффективный и сбалансированный двунаправленный промотор |
WO2017207480A1 (en) | 2016-05-30 | 2017-12-07 | Janssen Vaccines & Prevention B.V. | Stabilized pre-fusion rsv f proteins |
WO2018011196A1 (en) | 2016-07-14 | 2018-01-18 | Janssen Vaccines & Prevention B.V. | Hpv vaccines |
CN110062630A (zh) | 2016-12-12 | 2019-07-26 | 萨克生物研究学院 | 肿瘤靶向合成腺病毒及其用途 |
EP3624844A1 (en) | 2017-05-17 | 2020-03-25 | Janssen Vaccines & Prevention B.V. | Methods and compositions for inducing protective immunity against rsv infection |
EP3681533A1 (en) | 2017-09-15 | 2020-07-22 | Janssen Vaccines & Prevention B.V. | Method for the safe induction of immunity against rsv |
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-
2013
- 2013-03-11 CN CN201380013551.5A patent/CN104379733B/zh active Active
- 2013-03-11 HU HUE13708445A patent/HUE027839T2/en unknown
- 2013-03-11 AU AU2013231423A patent/AU2013231423B2/en active Active
- 2013-03-11 SI SI201330239A patent/SI2825640T1/sl unknown
- 2013-03-11 NZ NZ628385A patent/NZ628385A/en unknown
- 2013-03-11 EP EP13708445.5A patent/EP2825640B1/en active Active
- 2013-03-11 JP JP2014561393A patent/JP5770952B2/ja active Active
- 2013-03-11 ES ES13708445.5T patent/ES2582504T3/es active Active
- 2013-03-11 SG SG11201405228VA patent/SG11201405228VA/en unknown
- 2013-03-11 PL PL13708445.5T patent/PL2825640T3/pl unknown
- 2013-03-11 EA EA201491676A patent/EA034284B1/ru not_active IP Right Cessation
- 2013-03-11 WO PCT/EP2013/054846 patent/WO2013135615A1/en active Application Filing
- 2013-03-11 KR KR1020147026543A patent/KR102044051B1/ko active IP Right Grant
- 2013-03-11 DK DK13708445.5T patent/DK2825640T3/en active
- 2013-03-11 CA CA2864956A patent/CA2864956C/en active Active
- 2013-03-12 AR ARP130100798A patent/AR090318A1/es active IP Right Grant
- 2013-03-12 TW TW102108773A patent/TWI633188B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
AU2013231423B2 (en) | 2018-10-04 |
CN104379733B (zh) | 2016-01-20 |
NZ628385A (en) | 2016-09-30 |
KR20140139509A (ko) | 2014-12-05 |
SI2825640T1 (sl) | 2016-08-31 |
CA2864956A1 (en) | 2013-09-19 |
AU2013231423A1 (en) | 2014-08-28 |
EA201491676A1 (ru) | 2014-12-30 |
TW201336993A (zh) | 2013-09-16 |
PL2825640T3 (pl) | 2016-10-31 |
JP5770952B2 (ja) | 2015-08-26 |
ES2582504T3 (es) | 2016-09-13 |
EP2825640A1 (en) | 2015-01-21 |
SG11201405228VA (en) | 2014-11-27 |
CN104379733A (zh) | 2015-02-25 |
KR102044051B1 (ko) | 2019-11-12 |
TWI633188B (zh) | 2018-08-21 |
DK2825640T3 (en) | 2016-08-01 |
JP2015511597A (ja) | 2015-04-20 |
CA2864956C (en) | 2021-11-09 |
WO2013135615A1 (en) | 2013-09-19 |
EA034284B1 (ru) | 2020-01-24 |
HUE027839T2 (en) | 2016-11-28 |
EP2825640B1 (en) | 2016-04-27 |
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