CA2863259A1 - Irak inhibitors and uses thereof - Google Patents

Irak inhibitors and uses thereof Download PDF

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Publication number
CA2863259A1
CA2863259A1 CA2863259A CA2863259A CA2863259A1 CA 2863259 A1 CA2863259 A1 CA 2863259A1 CA 2863259 A CA2863259 A CA 2863259A CA 2863259 A CA2863259 A CA 2863259A CA 2863259 A1 CA2863259 A1 CA 2863259A1
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Canada
Prior art keywords
compound
disease
formula
pharmaceutically acceptable
ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2863259A
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English (en)
French (fr)
Inventor
Geraldine C. Harriman
Ronald T. Wester
Donna L. Romero
Shaughnessy Robinson
Mee Shelley
Matthew David Wessel
Jeremy Robert Greenwood
Craig E. Masse
Rosana Kapeller-Libermann
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Nimbus Iris Inc
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Nimbus Iris Inc
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Publication of CA2863259A1 publication Critical patent/CA2863259A1/en
Abandoned legal-status Critical Current

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    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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