CA2836385A1 - Method for treatment of advanced solid tumors - Google Patents

Method for treatment of advanced solid tumors Download PDF

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Publication number
CA2836385A1
CA2836385A1 CA2836385A CA2836385A CA2836385A1 CA 2836385 A1 CA2836385 A1 CA 2836385A1 CA 2836385 A CA2836385 A CA 2836385A CA 2836385 A CA2836385 A CA 2836385A CA 2836385 A1 CA2836385 A1 CA 2836385A1
Authority
CA
Canada
Prior art keywords
volasertib
day
advanced
solid tumours
hydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2836385A
Other languages
English (en)
French (fr)
Inventor
Tillmann Taube
Gerd Michael MUNZERT
Dorothea Rudolph
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim International GmbH
Original Assignee
Boehringer Ingelheim International GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46149422&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2836385(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH
Publication of CA2836385A1 publication Critical patent/CA2836385A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/282Platinum compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/243Platinum; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
CA2836385A 2011-05-17 2012-05-15 Method for treatment of advanced solid tumors Abandoned CA2836385A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11166365.4 2011-05-17
EP11166365 2011-05-17
PCT/EP2012/058959 WO2012156380A1 (en) 2011-05-17 2012-05-15 Method for treatment of advanced solid tumors

Publications (1)

Publication Number Publication Date
CA2836385A1 true CA2836385A1 (en) 2012-11-22

Family

ID=46149422

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2836385A Abandoned CA2836385A1 (en) 2011-05-17 2012-05-15 Method for treatment of advanced solid tumors

Country Status (15)

Country Link
US (1) US9370535B2 (zh)
EP (1) EP2709626A1 (zh)
JP (1) JP2014513705A (zh)
KR (1) KR20140025461A (zh)
CN (1) CN103533940A (zh)
AR (1) AR086422A1 (zh)
AU (1) AU2012257760A1 (zh)
BR (1) BR112013029484A2 (zh)
CA (1) CA2836385A1 (zh)
CL (1) CL2013003230A1 (zh)
EA (1) EA201301269A1 (zh)
IL (1) IL228908A0 (zh)
MX (1) MX2013013014A (zh)
UY (1) UY34076A (zh)
WO (1) WO2012156380A1 (zh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
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US8546566B2 (en) 2010-10-12 2013-10-01 Boehringer Ingelheim International Gmbh Process for manufacturing dihydropteridinones and intermediates thereof
US9358233B2 (en) 2010-11-29 2016-06-07 Boehringer Ingelheim International Gmbh Method for treating acute myeloid leukemia
US9370535B2 (en) 2011-05-17 2016-06-21 Boehringer Ingelheim International Gmbh Method for treatment of advanced solid tumors
JP2016525532A (ja) 2013-07-26 2016-08-25 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング 骨髄異形成症候群の処置
US9566280B2 (en) * 2014-01-28 2017-02-14 Massachusetts Institute Of Technology Combination therapies and methods of use thereof for treating cancer
US9867831B2 (en) 2014-10-01 2018-01-16 Boehringer Ingelheim International Gmbh Combination treatment of acute myeloid leukemia and myelodysplastic syndrome

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Also Published As

Publication number Publication date
MX2013013014A (es) 2014-01-31
EP2709626A1 (en) 2014-03-26
CN103533940A (zh) 2014-01-22
WO2012156380A1 (en) 2012-11-22
JP2014513705A (ja) 2014-06-05
US9370535B2 (en) 2016-06-21
US20130122111A1 (en) 2013-05-16
AR086422A1 (es) 2013-12-11
EA201301269A1 (ru) 2014-05-30
CL2013003230A1 (es) 2014-08-01
KR20140025461A (ko) 2014-03-04
IL228908A0 (en) 2013-12-31
UY34076A (es) 2012-11-30
AU2012257760A1 (en) 2013-10-31
BR112013029484A2 (pt) 2017-01-17

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FZDE Discontinued

Effective date: 20160516