CA2816426A1 - Alaninyl maytansinol antibody conjugates - Google Patents

Alaninyl maytansinol antibody conjugates Download PDF

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Publication number
CA2816426A1
CA2816426A1 CA2816426A CA2816426A CA2816426A1 CA 2816426 A1 CA2816426 A1 CA 2816426A1 CA 2816426 A CA2816426 A CA 2816426A CA 2816426 A CA2816426 A CA 2816426A CA 2816426 A1 CA2816426 A1 CA 2816426A1
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CA
Canada
Prior art keywords
antibody
receptor
drug
seq
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2816426A
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English (en)
French (fr)
Inventor
John Flygare
Jagath Reddy Junutula
Thomas Pillow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genentech Inc
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45217678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CA2816426(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CA2816426A1 publication Critical patent/CA2816426A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2816426A 2010-11-17 2011-11-16 Alaninyl maytansinol antibody conjugates Abandoned CA2816426A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41453510P 2010-11-17 2010-11-17
US61/414,535 2010-11-17
PCT/US2011/061031 WO2012074757A1 (en) 2010-11-17 2011-11-16 Alaninyl maytansinol antibody conjugates

Publications (1)

Publication Number Publication Date
CA2816426A1 true CA2816426A1 (en) 2012-06-07

Family

ID=45217678

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2816426A Abandoned CA2816426A1 (en) 2010-11-17 2011-11-16 Alaninyl maytansinol antibody conjugates

Country Status (7)

Country Link
US (1) US20120121615A1 (https=)
EP (1) EP2640727B1 (https=)
JP (1) JP5889912B2 (https=)
CN (1) CN103313990B (https=)
CA (1) CA2816426A1 (https=)
ES (1) ES2544608T3 (https=)
WO (1) WO2012074757A1 (https=)

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EP2640727B1 (en) 2015-05-13
JP2013544253A (ja) 2013-12-12
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CN103313990A (zh) 2013-09-18
JP5889912B2 (ja) 2016-03-22

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