CA2813330A1 - Process for purifying cyclolipopeptide compounds or the salts thereof - Google Patents

Process for purifying cyclolipopeptide compounds or the salts thereof Download PDF

Info

Publication number
CA2813330A1
CA2813330A1 CA2813330A CA2813330A CA2813330A1 CA 2813330 A1 CA2813330 A1 CA 2813330A1 CA 2813330 A CA2813330 A CA 2813330A CA 2813330 A CA2813330 A CA 2813330A CA 2813330 A1 CA2813330 A1 CA 2813330A1
Authority
CA
Canada
Prior art keywords
adsorption resin
compound
formula
xad
process according
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2813330A
Other languages
English (en)
French (fr)
Inventor
Zhaoli Zhang
Shidong Liu
Zhonghao Zhuo
Xiaoming Ji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Techwell Biopharmaceutical Co Ltd
Original Assignee
Shanghai Techwell Biopharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Techwell Biopharmaceutical Co Ltd filed Critical Shanghai Techwell Biopharmaceutical Co Ltd
Publication of CA2813330A1 publication Critical patent/CA2813330A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
CA2813330A 2010-09-29 2011-09-27 Process for purifying cyclolipopeptide compounds or the salts thereof Abandoned CA2813330A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN201010297406.2 2010-09-29
CN201010297406 2010-09-29
PCT/CN2011/080220 WO2012041218A1 (zh) 2010-09-29 2011-09-27 一种环脂肽化合物或其盐的纯化方法

Publications (1)

Publication Number Publication Date
CA2813330A1 true CA2813330A1 (en) 2012-04-05

Family

ID=45891956

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2813330A Abandoned CA2813330A1 (en) 2010-09-29 2011-09-27 Process for purifying cyclolipopeptide compounds or the salts thereof

Country Status (10)

Country Link
US (1) US8927690B2 (ja)
EP (1) EP2623511B1 (ja)
JP (1) JP6000254B2 (ja)
KR (1) KR101514903B1 (ja)
CN (1) CN102432674B (ja)
AU (1) AU2011307731B2 (ja)
CA (1) CA2813330A1 (ja)
ES (1) ES2581562T3 (ja)
RU (1) RU2535489C1 (ja)
WO (1) WO2012041218A1 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102432674B (zh) 2010-09-29 2014-01-22 上海天伟生物制药有限公司 一种环脂肽化合物或其盐的纯化方法
EP2623611B1 (en) * 2010-09-30 2016-07-13 Shanghai Techwell Biopharmaceutical Co., Ltd Method for purifying cyclic lipopeptide or salt thereof
SI2699327T1 (sl) * 2011-04-20 2015-11-30 Xelia Pharmaceuticals Aps Postopek čiščenja mikafungina
CN102627688B (zh) * 2012-03-30 2014-12-31 上海天伟生物制药有限公司 一种高纯度环肽化合物及其制备方法和用途
CN102627689B (zh) * 2012-03-30 2014-08-06 上海天伟生物制药有限公司 一种环肽类化合物的水合物及其制备方法和用途
CN102911257B (zh) * 2012-09-21 2014-02-12 无锡市第四人民医院 环脂肽类抗生素及其制备和应用
CN104418940A (zh) * 2013-08-28 2015-03-18 重庆乾泰生物医药有限公司 一种高纯度环己肽类化合物的制备方法
CN103965298B (zh) * 2014-05-23 2016-08-10 浙江海正药业股份有限公司 一种阿尼芬净的纯化方法
CN104926701B (zh) * 2015-06-30 2017-05-03 西安蓝晓科技新材料股份有限公司 一种蛋氨酸纯化的工艺
SG11201805618UA (en) * 2015-12-31 2018-07-30 Dev Ct Biotechnology Process for preparing a crassocephalum crepidioides extract, extract prepared thereby and use of the extract
CN106755221A (zh) * 2016-11-28 2017-05-31 无锡福祈制药有限公司 一种米卡芬净母核fr179642的制备方法
CN111434675A (zh) * 2019-01-11 2020-07-21 苏州纳微科技股份有限公司 一种米卡芬净母环的分离纯化方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4874843A (en) * 1987-12-03 1989-10-17 Eli Lilly And Company Chromatographic purification process
GB8925593D0 (en) 1989-11-13 1990-01-04 Fujisawa Pharmaceutical Co Fr901379 substance and preparation thereof
FI912873A (fi) * 1990-06-18 1991-12-19 Fujisawa Pharmaceutical Co Ny polypeptidfoerening och foerfarande foer dess framstaellning.
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
US5552521A (en) * 1995-02-10 1996-09-03 Merck & Co., Inc. Process for preparing certain aza cyclohexapeptides
EP0933422A4 (en) * 1996-06-13 2005-02-02 Fujisawa Pharmaceutical Co CYCLIC LIPOPEPTIDE ACYLASE
CN1337968A (zh) * 1998-12-09 2002-02-27 伊莱利利公司 蓝刺菌素环肽化合物的纯化
CN1371423A (zh) * 1999-07-02 2002-09-25 藤泽药品工业株式会社 编码环状脂肽酰基转移酶的基因及其表达
US6960360B2 (en) 2000-08-31 2005-11-01 Phenolics, Llc Efficient method for producing compositions enriched in total phenols
WO2002068456A1 (en) 2001-02-26 2002-09-06 Fujisawa Pharmaceutical Co., Ltd. Echinocandin derivatives, pharmaceutical compositions containing same and use thereof as drugs
DE102004060750A1 (de) * 2004-12-15 2006-07-13 Sanofi-Aventis Deutschland Gmbh Verfahren zur Deacylierung von Lipopeptiden
US9394340B2 (en) * 2009-03-24 2016-07-19 Cadila Healthcare Limited Purification process for lipopeptides
CN102432674B (zh) 2010-09-29 2014-01-22 上海天伟生物制药有限公司 一种环脂肽化合物或其盐的纯化方法
EP2623611B1 (en) * 2010-09-30 2016-07-13 Shanghai Techwell Biopharmaceutical Co., Ltd Method for purifying cyclic lipopeptide or salt thereof

Also Published As

Publication number Publication date
RU2535489C1 (ru) 2014-12-10
RU2013118532A (ru) 2014-11-10
US8927690B2 (en) 2015-01-06
KR101514903B1 (ko) 2015-04-23
JP2013538832A (ja) 2013-10-17
KR20130059454A (ko) 2013-06-05
AU2011307731B2 (en) 2016-02-18
CN102432674B (zh) 2014-01-22
US20130281665A1 (en) 2013-10-24
EP2623511B1 (en) 2016-04-06
JP6000254B2 (ja) 2016-09-28
CN102432674A (zh) 2012-05-02
ES2581562T3 (es) 2016-09-06
EP2623511A4 (en) 2014-04-16
EP2623511A1 (en) 2013-08-07
WO2012041218A1 (zh) 2012-04-05
AU2011307731A1 (en) 2013-05-23

Similar Documents

Publication Publication Date Title
EP2623511B1 (en) Process for purifying cyclic lipopeptide compounds or salts thereof
US8877777B2 (en) Process for purifying cyclolipopeptide compounds or the salts thereof
CA2796488C (en) Purification method of azacyclohexapeptide or its salt
CA2662923A1 (en) Purification processes of echinocandin-type compounds
US9045515B2 (en) Procedure for the purification of tiacumicin B
CA2794688C (en) A process for purification of pneumocandin
WO2012089103A1 (zh) 一种环己肽类化合物及其盐的分离纯化方法
JP5483127B2 (ja) 銀イオン溶液抽出を利用した不飽和アルキル基を有するラクトン化合物の精製方法
CN104418940A (zh) 一种高纯度环己肽类化合物的制备方法
HRP980604A2 (en) Purification process

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20170927