CA2786692A1 - Biomarkers of immunomodulatory effects in humans treated with anti-cd200 antibodies - Google Patents
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- CA2786692A1 CA2786692A1 CA2786692A CA2786692A CA2786692A1 CA 2786692 A1 CA2786692 A1 CA 2786692A1 CA 2786692 A CA2786692 A CA 2786692A CA 2786692 A CA2786692 A CA 2786692A CA 2786692 A1 CA2786692 A1 CA 2786692A1
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
- G01N2333/70517—CD8
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70596—Molecules with a "CD"-designation not provided for elsewhere in G01N2333/705
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
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- Life Sciences & Earth Sciences (AREA)
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Applications Claiming Priority (9)
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| US29406610P | 2010-01-11 | 2010-01-11 | |
| US61/294,066 | 2010-01-11 | ||
| US33799710P | 2010-02-11 | 2010-02-11 | |
| US61/337,997 | 2010-02-11 | ||
| US40144210P | 2010-08-12 | 2010-08-12 | |
| US61/401,442 | 2010-08-12 | ||
| US41697410P | 2010-11-24 | 2010-11-24 | |
| US61/416,974 | 2010-11-24 | ||
| PCT/US2011/020750 WO2011085343A1 (en) | 2010-01-11 | 2011-01-11 | Biomarkers of immunomodulatory effects in humans treated with anti-cd200 antibodies |
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| CA2786692A Abandoned CA2786692A1 (en) | 2010-01-11 | 2011-01-11 | Biomarkers of immunomodulatory effects in humans treated with anti-cd200 antibodies |
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| EP (1) | EP2523976B1 (forum.php) |
| JP (2) | JP6012473B2 (forum.php) |
| KR (1) | KR20130005264A (forum.php) |
| CN (1) | CN102906115A (forum.php) |
| AU (1) | AU2011203879A1 (forum.php) |
| CA (1) | CA2786692A1 (forum.php) |
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| RU (1) | RU2012134369A (forum.php) |
| SG (1) | SG182408A1 (forum.php) |
| WO (1) | WO2011085343A1 (forum.php) |
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| US11090363B2 (en) | 2009-07-10 | 2021-08-17 | University of Pittsburgh—of the Commonwealth System of Higher Education | Vasoactive intestinal peptide release from microparticles |
| WO2011006029A1 (en) | 2009-07-10 | 2011-01-13 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Artificial cell constructs for inducing immunological tolerance |
| US9085623B2 (en) | 2010-02-11 | 2015-07-21 | Alexion Pharmaceuticals, Inc. | Therapeutic methods using anti-CD200 antibodies |
| TW201244737A (en) | 2011-02-03 | 2012-11-16 | Alexion Pharma Inc | Use of an anti-CD200 antibody for prolonging the survival of allografts |
| CN102698266A (zh) * | 2012-05-15 | 2012-10-03 | 中国医学科学院北京协和医院 | Cd200在制备系统性红斑狼疮治疗药物中的应用 |
| SG11201408646VA (en) | 2012-07-06 | 2015-01-29 | Genmab Bv | Dimeric protein with triple mutations |
| KR102121369B1 (ko) * | 2013-02-14 | 2020-06-11 | 파론 파머수티컬스 오와이 | 급성 호흡 곤란 증후군 (ards) 관련 바이오마커를 결정하는 방법, 환자의 ards 의 발달을 모니터링하고 치료하는 방법 |
| CN109069627A (zh) * | 2016-01-14 | 2018-12-21 | 纪念斯隆-凯特琳癌症中心 | 对foxp3衍生肽特异性的t细胞受体样抗体 |
| GB201608197D0 (en) * | 2016-05-10 | 2016-06-22 | Ducentis Biotherapeutics Ltd | Novel proteins |
| WO2018075408A1 (en) | 2016-10-17 | 2018-04-26 | Alexion Pharmaceuticals, Inc. | Methods of treating acute myeloid leukemia (aml) with combinations of anti-cd200 antibodies, cytarabine, and daunorubicin |
| WO2018102594A1 (en) | 2016-12-01 | 2018-06-07 | Alexion Pharmaceuticals, Inc. | Methods of treating solid tumors with anti-cd200 antibodies |
| CN118184781A (zh) * | 2017-05-08 | 2024-06-14 | 阿迪马布有限责任公司 | 抗cd3结合结构域和包含它们的抗体以及它们的产生及使用方法 |
| WO2019067499A1 (en) | 2017-09-27 | 2019-04-04 | Alexion Pharmaceuticals, Inc. | BIOMARKER SIGNATURE FOR PREDICTING A TUMOR RESPONSE TO ANTI-CD200 THERAPY |
| WO2019126536A1 (en) | 2017-12-20 | 2019-06-27 | Alexion Pharmaceuticals Inc. | Humanized anti-cd200 antibodies and uses thereof |
| US12139533B2 (en) | 2017-12-20 | 2024-11-12 | Alexion Pharmaceuticals, Inc. | Liquid formulations of anti-CD200 antibodies |
| TWI749367B (zh) * | 2018-09-14 | 2021-12-11 | 美商美國禮來大藥廠 | Cd200r促效劑抗體及其用途 |
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2011
- 2011-01-11 SG SG2012050142A patent/SG182408A1/en unknown
- 2011-01-11 WO PCT/US2011/020750 patent/WO2011085343A1/en not_active Ceased
- 2011-01-11 US US13/521,671 patent/US9180186B2/en active Active
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- 2011-01-11 CA CA2786692A patent/CA2786692A1/en not_active Abandoned
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| MX2012008108A (es) | 2012-10-03 |
| JP2015155465A (ja) | 2015-08-27 |
| US9180186B2 (en) | 2015-11-10 |
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| US20130202602A1 (en) | 2013-08-08 |
| EP2523976A1 (en) | 2012-11-21 |
| NZ601111A (en) | 2014-07-25 |
| JP6012473B2 (ja) | 2016-10-25 |
| EP2523976B1 (en) | 2018-04-25 |
| US20160033514A1 (en) | 2016-02-04 |
| EP2523976A4 (en) | 2013-10-30 |
| WO2011085343A1 (en) | 2011-07-14 |
| CN102906115A (zh) | 2013-01-30 |
| IN2012DN06309A (forum.php) | 2015-09-25 |
| AU2011203879A1 (en) | 2012-08-02 |
| KR20130005264A (ko) | 2013-01-15 |
| SG182408A1 (en) | 2012-08-30 |
| JP2013516494A (ja) | 2013-05-13 |
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