CA2785599A1 - Purified bowman-birk protease inhibitor proteins isolated from a soy processing stream - Google Patents

Purified bowman-birk protease inhibitor proteins isolated from a soy processing stream Download PDF

Info

Publication number
CA2785599A1
CA2785599A1 CA2785599A CA2785599A CA2785599A1 CA 2785599 A1 CA2785599 A1 CA 2785599A1 CA 2785599 A CA2785599 A CA 2785599A CA 2785599 A CA2785599 A CA 2785599A CA 2785599 A1 CA2785599 A1 CA 2785599A1
Authority
CA
Canada
Prior art keywords
bbi
seq
protein
product
stream
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2785599A
Other languages
English (en)
French (fr)
Inventor
Charles S. Schasteen
Darrell Marsh
Karsten Keller
Marlene Mekel
Jennifer Wu
Barry Tulk
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Solae LLC
Original Assignee
Solae LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Solae LLC filed Critical Solae LLC
Publication of CA2785599A1 publication Critical patent/CA2785599A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17—Amino acids, peptides or proteins
    • A23L33/185—Vegetable proteins
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/14—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from leguminous or other vegetable seeds; from press-cake or oil-bearing seeds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J3/00—Working-up of proteins for foodstuffs
    • A23J3/14—Vegetable proteins
    • A23J3/16—Vegetable proteins from soybean
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nutrition Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Dairy Products (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2785599A 2009-12-30 2010-12-30 Purified bowman-birk protease inhibitor proteins isolated from a soy processing stream Abandoned CA2785599A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29131209P 2009-12-30 2009-12-30
US61/291,312 2009-12-30
PCT/US2010/062553 WO2011082335A2 (en) 2009-12-30 2010-12-30 Purified bowman-birk protease inhibitor proteins isolated from a soy processing stream

Publications (1)

Publication Number Publication Date
CA2785599A1 true CA2785599A1 (en) 2011-07-07

Family

ID=44226820

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2785599A Abandoned CA2785599A1 (en) 2009-12-30 2010-12-30 Purified bowman-birk protease inhibitor proteins isolated from a soy processing stream
CA2785736A Abandoned CA2785736A1 (en) 2009-12-30 2010-12-30 Method for recovering bowman-birk inhibitor proteins from a soy processing stream

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2785736A Abandoned CA2785736A1 (en) 2009-12-30 2010-12-30 Method for recovering bowman-birk inhibitor proteins from a soy processing stream

Country Status (7)

Country Link
US (5) US20130023480A1 (enExample)
EP (5) EP2519251A4 (enExample)
JP (5) JP2013516431A (enExample)
CN (6) CN103988973A (enExample)
BR (2) BR112012016225A2 (enExample)
CA (2) CA2785599A1 (enExample)
WO (5) WO2011082360A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104902960A (zh) * 2012-07-26 2015-09-09 索莱有限责任公司 用于个人护理产品和工业产品中的乳化剂

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2504373C2 (ru) 2008-03-26 2014-01-20 ОРАМЕД Лтд. Способы и композиции для перорального введения протеинов
US20140141126A1 (en) * 2011-06-29 2014-05-22 Solae Llc Baked food compositions comprising soy whey proteins that have been isolated from processing streams
ES2912138T3 (es) * 2012-02-01 2022-05-24 Oramed Ltd Composiciones que contienen inhibidores de proteasa, composiciones que comprenden las mismas y métodos para producir y usar las misma
EP2877063A2 (en) * 2012-07-26 2015-06-03 Solae, LLC Foaming agent for use in personal care products and industrial products
EP2877040A1 (en) * 2012-07-26 2015-06-03 Solae, LLC Emulsifying agent for use in food compositions
EP2877039A1 (en) * 2012-07-26 2015-06-03 Solae, LLC Foaming agent for use in food compositions
WO2014064132A1 (en) 2012-10-23 2014-05-01 Upfront Chromatography A/S Separation processes for soy protein
CN104902921A (zh) 2013-01-03 2015-09-09 奥拉姆德有限公司 用于治疗nafld、肝性脂肪变性及其后遗症的方法和组合物
FR3001362B1 (fr) 2013-01-31 2015-07-10 Roquette Freres Procede de fractionnement des solubles de pois, fractions obtenues et leur valorisation
CN103392907B (zh) * 2013-06-08 2014-12-17 东北农业大学 酶法修饰改善乳清蛋白纳米纤维聚合量的方法
WO2015101435A1 (en) * 2013-12-30 2015-07-09 Koninklijke Philips N.V. A method of making soymilk
US10457704B2 (en) 2014-01-29 2019-10-29 Upfront Chromatography A/S Separation processes for pea protein
CN103933548A (zh) * 2014-04-17 2014-07-23 中国药科大学 露那辛多肽在防治白内障药物中的应用
US11291221B2 (en) 2015-10-30 2022-04-05 Beth Israel Deaconess Medical Center, Inc. Methods for determination of bioactivity, quantity, removal, or inactivation of cereal amylase trypsin inhibitors in cereals, flours, plants, and complex foods
US10858390B2 (en) * 2016-09-02 2020-12-08 Cem Corporation Use of excess carbodiimide for peptide synthesis at elevated temperatures
CA3055986C (en) 2017-03-31 2025-09-16 J.R. Simplot Company POTATO PROTEIN POWDERS
CN107488226A (zh) * 2017-09-06 2017-12-19 成都晟博源生物工程有限公司 一种大豆胰蛋白酶抑制剂的提取方法
CN110872140B (zh) * 2018-09-03 2022-06-21 中国石油化工股份有限公司 危化品分离回收系统
CN110104754B (zh) * 2019-04-03 2022-03-29 江苏农林职业技术学院 一种豆制品废水废渣处理甲基橙染料废水的方法
CN110551209A (zh) * 2019-08-27 2019-12-10 合肥天汇孵化科技有限公司 一种基于大豆深加工废液以豆清水为原料粗提sbti蛋白工艺
CA3157446A1 (en) * 2019-11-20 2021-05-27 Csl Behring Ag Method for extracting a protein from a precipitate and method for precipitating impurities
EP4110071A4 (en) * 2020-02-26 2024-02-14 Eat Just, Inc. Pulse protein isolation by ultrafiltration
US20230227487A1 (en) * 2020-06-12 2023-07-20 Basf Se Improved demineralization of fermentation broths and purification of fine chemicals such as oligosaccharides

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4368151A (en) * 1981-08-10 1983-01-11 A. E. Staley Manufacturing Company 7S And 11S vegetable protein fractionation and isolation
US5288856A (en) * 1986-11-20 1994-02-22 Pierre Amiguet Method of isolating acid-stable, biologically active proteins
US4808314A (en) * 1987-09-18 1989-02-28 Scripps Clinic And Research Foundation Method for reducing bacterial endotoxin contamination in solutions of macromolecules
US5250515A (en) * 1988-04-11 1993-10-05 Monsanto Company Method for improving the efficacy of insect toxins
TR24186A (tr) * 1988-04-11 1991-05-30 Monsanto Co Hasere zehirlerinin etkinligini arttirmak icin yoentem
JPH06145198A (ja) * 1992-03-30 1994-05-24 Shokuhin Sangyo High Separeeshiyon Syst Gijutsu Kenkyu Kumiai 大豆トリプシンインヒビターの製造方法
DK46793D0 (da) * 1993-04-26 1993-04-26 Novo Nordisk As Enzym
JPH1066572A (ja) * 1996-08-29 1998-03-10 Showa Sangyo Co Ltd 高純度の大豆トリプシンインヒビターの製造方法
US6313273B1 (en) * 1999-08-25 2001-11-06 Abbott Laboratories Soy proteins and methods for their production
US7175869B2 (en) * 2000-11-30 2007-02-13 Kraft Foods Holdings, Inc. Method of deflavoring soy-derived materials using electrodialysis
US6787173B2 (en) * 2000-11-30 2004-09-07 Kraft Foods Holdings, Inc. Method of deflavoring soy-derived materials
CN1150831C (zh) * 2001-01-19 2004-05-26 北京中联捷思科技发展有限公司 超滤提取大豆乳清蛋白的方法
US6927322B2 (en) * 2001-03-30 2005-08-09 Cornell Research Foundation, Inc. Cabbage proteinase inhibitor gene confers resistance against plant pests
US7214394B2 (en) * 2002-05-31 2007-05-08 Archer-Daniels-Midland Company Policosanol compositions, extraction from novel sources, and uses thereof
CN100506062C (zh) * 2002-08-28 2009-07-01 不二制油株式会社 酸性大豆蛋白质凝胶食物及其生产方法
WO2004104036A1 (ja) * 2003-05-21 2004-12-02 Fuji Oil Company, Limited 大豆ホエー蛋白及び大豆ホエー蛋白分解物の製造法
US20070277269A1 (en) * 2006-04-17 2007-11-29 Ceres, Inc. Nucleotide sequences and polypeptides encoded thereby useful for modifying plant characteristics
JP2007510431A (ja) * 2003-11-05 2007-04-26 ケリー グループ サーヴィシーズ インターナショナル、リミテッド 酸安定大豆タンパク及び強化食品又は飲料
CA2544820C (en) * 2003-11-06 2014-02-18 Genencor International, Inc. Bacterial expression of protease inhibitors and variants thereof
EP1689766B1 (en) * 2003-11-06 2012-04-25 Danisco US Inc. Expression in filamentous fungi of protease inhibitors and variants thereof
CN1615722A (zh) * 2003-11-14 2005-05-18 哈高科大豆食品有限责任公司 超滤膜分离技术制备大豆分离蛋白的方法
EP1738654A4 (en) * 2004-02-26 2009-07-22 Fuji Oil Co Ltd SOY PROTEIN (S) SOLUTION AND GEL
JP4912875B2 (ja) * 2004-02-27 2012-04-11 不二製油株式会社 癌転移抑制組成物
US20060057275A1 (en) * 2004-09-16 2006-03-16 Shaowen Wu Process for the preparation of glycinin-rich and beta-conglycinin-rich protein fractions
BRPI0613548A2 (pt) * 2005-05-05 2011-01-18 Genencor Int composições de cuidado pessoal e métodos para seu uso
US20070054031A1 (en) * 2005-09-02 2007-03-08 Keshun Liu Methods of extracting, concentrating and fractionating proteins and other chemical components
TWI257723B (en) * 2005-09-15 2006-07-01 Epitech Technology Corp Vertical light-emitting diode and method for manufacturing the same
US20080182002A1 (en) * 2007-01-26 2008-07-31 Solae, Llc Processes for Removing Bitter Components from Soy Protein Isolates
EP2166872A1 (en) * 2007-07-03 2010-03-31 Solae, LLC Modified vegetable protein having low levels of phytic acid, isoflavones, and ash
CN101367018A (zh) * 2007-09-13 2009-02-18 中国海洋大学 壳聚糖树脂固定化酶纯化大豆乳清废水中胰蛋白酶抑制剂的工艺
CA2740197A1 (en) * 2008-10-15 2010-04-22 Danisco Us Inc. Modified variant bowman birk protease inhibitors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104902960A (zh) * 2012-07-26 2015-09-09 索莱有限责任公司 用于个人护理产品和工业产品中的乳化剂

Also Published As

Publication number Publication date
EP2519535A1 (en) 2012-11-07
EP2519535A4 (en) 2013-08-28
CN102781255A (zh) 2012-11-14
CA2785736A1 (en) 2011-07-07
JP2015157873A (ja) 2015-09-03
WO2011082360A1 (en) 2011-07-07
CN102781459A (zh) 2012-11-14
EP2519245A1 (en) 2012-11-07
US20120329993A1 (en) 2012-12-27
WO2011082335A3 (en) 2011-08-18
JP2013516429A (ja) 2013-05-13
JP2013516432A (ja) 2013-05-13
US20120289683A1 (en) 2012-11-15
EP2519251A2 (en) 2012-11-07
CN102770439A (zh) 2012-11-07
US20130023649A1 (en) 2013-01-24
EP2519117A1 (en) 2012-11-07
CN102781255B (zh) 2015-11-25
CN102762584A (zh) 2012-10-31
US20120302736A1 (en) 2012-11-29
CN103988973A (zh) 2014-08-20
WO2011082338A1 (en) 2011-07-07
US20130023480A1 (en) 2013-01-24
BR112012016232A2 (pt) 2017-03-07
CN102770147A (zh) 2012-11-07
WO2011082335A2 (en) 2011-07-07
EP2519251A4 (en) 2013-08-28
BR112012016225A2 (pt) 2017-03-07
EP2519245A4 (en) 2013-08-28
WO2011082359A1 (en) 2011-07-07
EP2519117A4 (en) 2016-11-09
JP2013516431A (ja) 2013-05-13
WO2011082358A1 (en) 2011-07-07
JP2013516427A (ja) 2013-05-13
EP2785730A1 (en) 2014-10-08

Similar Documents

Publication Publication Date Title
US20130023480A1 (en) Purified Bowman-Birk Protease Inhibitor Proteins Isolated from a Soy Processing Sttream
EP2681231B1 (en) Method for isolating osteopontin using concentrated feeds
US20050037474A9 (en) Method for controlling the yield and purity of proteinase inhibitor II during extraction
WO2003003835A1 (en) Method for controlling the yield and purity of proteinase inhibitor ii during extraction
CN120366409A (zh) 一种利用脱脂蛋黄粉酶解制备并富集分离多种蛋黄生物活性肽的方法及应用
CN104693272A (zh) 牦牛乳乳清蛋白具有抗氧化活性的三肽及其应用和组合物
CN114990181B (zh) 一种抗衰老的大豆肽及其制备方法和应用
US20030077265A1 (en) Isolation and purification of proteinase inhibitor ll
Salvado et al. Enzymatic production of bioactive peptides from whey proteins: Their active role and potential health benefits
BR102012016983A2 (pt) Método para recuperar a proteína de soro de leite de soja e composição de proteína de soro de leite de soja
WO2003003837A1 (en) Isolation and purification of proteinase inhibitor ii
NZ614874B2 (en) Method for isolating osteopontin using concentrated feeds
HK1162127B (en) Oil body associated protein compositions and methods as well as use thereof for reducing the risk of cardiovascular disease

Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20141230