CA2784526C - Process for the preparation of chelated compounds - Google Patents
Process for the preparation of chelated compounds Download PDFInfo
- Publication number
- CA2784526C CA2784526C CA2784526A CA2784526A CA2784526C CA 2784526 C CA2784526 C CA 2784526C CA 2784526 A CA2784526 A CA 2784526A CA 2784526 A CA2784526 A CA 2784526A CA 2784526 C CA2784526 C CA 2784526C
- Authority
- CA
- Canada
- Prior art keywords
- metal
- process according
- chelated
- chelating agent
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/38—Separation; Purification; Stabilisation; Use of additives
- C07C227/40—Separation; Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP09179438A EP2338874A1 (en) | 2009-12-16 | 2009-12-16 | Process for the preparation of chelated compounds |
| EP09179438.8 | 2009-12-16 | ||
| PCT/EP2010/069715 WO2011073236A1 (en) | 2009-12-16 | 2010-12-15 | Process for the preparation of chelated compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2784526A1 CA2784526A1 (en) | 2011-06-23 |
| CA2784526C true CA2784526C (en) | 2014-09-30 |
Family
ID=41800716
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2784526A Active CA2784526C (en) | 2009-12-16 | 2010-12-15 | Process for the preparation of chelated compounds |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US8987508B2 (enExample) |
| EP (2) | EP2338874A1 (enExample) |
| JP (1) | JP5838164B2 (enExample) |
| KR (1) | KR101766280B1 (enExample) |
| CN (1) | CN102712574B (enExample) |
| AU (1) | AU2010332960C1 (enExample) |
| BR (1) | BR112012014621B8 (enExample) |
| CA (1) | CA2784526C (enExample) |
| ES (1) | ES2474515T3 (enExample) |
| HR (1) | HRP20140430T1 (enExample) |
| IL (1) | IL220414A0 (enExample) |
| MX (1) | MX2012006954A (enExample) |
| NZ (1) | NZ600910A (enExample) |
| PL (1) | PL2513043T3 (enExample) |
| PT (1) | PT2513043E (enExample) |
| RU (1) | RU2533833C2 (enExample) |
| SG (1) | SG181776A1 (enExample) |
| WO (1) | WO2011073236A1 (enExample) |
| ZA (1) | ZA201205192B (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ628481A (en) * | 2012-01-11 | 2016-11-25 | Adelaide Res & Innovation Pty | Stabilising and analysing fatty acids in a biological sample stored on solid media |
| CN102603550B (zh) * | 2012-02-16 | 2014-11-26 | 佛山普正医药科技有限公司 | 一种中间体bopta的制备方法 |
| CN103664672B (zh) * | 2013-10-21 | 2016-01-13 | 河北一品制药有限公司 | 一种工业化生产钆喷酸葡胺的制备方法 |
| US10696562B2 (en) * | 2013-12-05 | 2020-06-30 | Colorado School Of Mines | Upgrade of yttrium in a mixed rare earth stream using iminodiacetic acid functionalized resin |
| EP2977369A1 (en) * | 2014-07-24 | 2016-01-27 | Bracco Imaging SPA | Preparation of a solid form of gadobenate dimeglumine |
| GB201421162D0 (en) | 2014-11-28 | 2015-01-14 | Ge Healthcare As | Lanthanide complex formulations |
| GB201421161D0 (en) * | 2014-11-28 | 2015-01-14 | Ge Healthcare As | Metal complex formulations |
| CN109608350B (zh) * | 2018-12-29 | 2021-06-22 | 湖北壮美生物科技有限公司 | 一种工业化制备甘氨酸钙的装置及相应的甘氨酸钙生产方法 |
| WO2020159399A1 (ru) * | 2019-01-31 | 2020-08-06 | Акционерное Общество "Биоамид" | Способ получения комплексной микроэлементной добавки в корма на основе органических соединений железа, марганца, цинка, меди, кобальта |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3172898A (en) * | 1965-03-09 | Process for preparation of metal chelates of aminopolycarboxylic acid compounds | ||
| SU138608A1 (ru) * | 1960-07-14 | 1960-11-30 | Т.В. Лищенко | Способ получени алюминиевой соли этилендиаминтетрауксусной кислоты |
| NL194579C (nl) * | 1983-01-21 | 2002-08-05 | Schering Ag | Diagnostisch middel. |
| DE3580721D1 (de) * | 1984-08-06 | 1991-01-10 | Westinghouse Electric Corp | Verfahren zur trennung von gadoliniumisotopen. |
| US4711768A (en) * | 1984-08-06 | 1987-12-08 | Westinghouse Electric Corp. | Process for the separation of gadolinium isotopes |
| IT1213029B (it) * | 1986-01-30 | 1989-12-07 | Bracco Ind Chimica Spa | Chelati di ioni metallici paramagnetici. |
| DE3922005A1 (de) * | 1989-06-30 | 1991-01-10 | Schering Ag | Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung |
| AU625529B2 (en) * | 1989-12-22 | 1992-07-16 | E.R. Squibb & Sons, Inc. | 10-(2'-hydroxy-3'-alkoxy-1,4,7-triscarboxymethyl-1,4,7,10- tetraazacyclododecanes |
| US5262018A (en) * | 1991-08-12 | 1993-11-16 | Fmc Corporation | Metals removal from aqueous peroxy acids or peroxy salts |
| IT1269839B (it) | 1994-05-26 | 1997-04-15 | Bracco Spa | Coniugati di acidi biliari, loro derivati con complessi metallici e relativi usi |
| IT1283218B1 (it) * | 1996-03-08 | 1998-04-16 | Bracco Spa | Polichelanti, loro complessi con ioni metallici, loro preparazione e loro usi |
| GB9707880D0 (en) * | 1997-04-18 | 1997-06-04 | Nycomed Imaging As | Contrast agent preparation |
| ITMI981583A1 (it) | 1998-07-10 | 2000-01-10 | Bracco Spa | Processo per la preparazione dell'acido 4 -carbossi-5,8,11-tris (carbossimetil)-1-fenil-2-oxa-5,8,11-triazatridecan-13-oico |
| US6342598B1 (en) * | 1998-11-26 | 2002-01-29 | Bracco International B.V. | Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents |
| EP1762563A1 (en) | 2005-09-13 | 2007-03-14 | BRACCO IMAGING S.p.A. | Process for the preparation of contrast agents |
| US20090208421A1 (en) * | 2008-02-19 | 2009-08-20 | Dominique Meyer | Process for preparing a pharmaceutical formulation of contrast agents |
-
2009
- 2009-12-16 EP EP09179438A patent/EP2338874A1/en not_active Withdrawn
-
2010
- 2010-12-15 HR HRP20140430AT patent/HRP20140430T1/hr unknown
- 2010-12-15 NZ NZ600910A patent/NZ600910A/en not_active IP Right Cessation
- 2010-12-15 MX MX2012006954A patent/MX2012006954A/es active IP Right Grant
- 2010-12-15 BR BR112012014621A patent/BR112012014621B8/pt active IP Right Grant
- 2010-12-15 US US13/514,394 patent/US8987508B2/en active Active
- 2010-12-15 CA CA2784526A patent/CA2784526C/en active Active
- 2010-12-15 PT PT107909723T patent/PT2513043E/pt unknown
- 2010-12-15 JP JP2012543706A patent/JP5838164B2/ja active Active
- 2010-12-15 WO PCT/EP2010/069715 patent/WO2011073236A1/en not_active Ceased
- 2010-12-15 SG SG2012044780A patent/SG181776A1/en unknown
- 2010-12-15 RU RU2012129982/04A patent/RU2533833C2/ru active
- 2010-12-15 KR KR1020127017584A patent/KR101766280B1/ko active Active
- 2010-12-15 PL PL10790972T patent/PL2513043T3/pl unknown
- 2010-12-15 ES ES10790972.3T patent/ES2474515T3/es active Active
- 2010-12-15 CN CN201080061506.3A patent/CN102712574B/zh active Active
- 2010-12-15 EP EP10790972.3A patent/EP2513043B1/en active Active
- 2010-12-15 AU AU2010332960A patent/AU2010332960C1/en active Active
-
2012
- 2012-06-14 IL IL220414A patent/IL220414A0/en active IP Right Grant
- 2012-07-12 ZA ZA2012/05192A patent/ZA201205192B/en unknown
-
2015
- 2015-02-16 US US14/623,202 patent/US9567350B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| RU2012129982A (ru) | 2014-01-27 |
| MX2012006954A (es) | 2012-07-30 |
| IL220414A0 (en) | 2012-08-30 |
| EP2338874A1 (en) | 2011-06-29 |
| KR101766280B1 (ko) | 2017-08-08 |
| US20120245333A1 (en) | 2012-09-27 |
| WO2011073236A1 (en) | 2011-06-23 |
| HRP20140430T1 (hr) | 2014-07-18 |
| EP2513043B1 (en) | 2014-03-26 |
| US8987508B2 (en) | 2015-03-24 |
| US9567350B2 (en) | 2017-02-14 |
| BR112012014621A2 (pt) | 2016-03-01 |
| AU2010332960C1 (en) | 2014-01-23 |
| SG181776A1 (en) | 2012-07-30 |
| JP2013514311A (ja) | 2013-04-25 |
| CN102712574A (zh) | 2012-10-03 |
| KR20120101525A (ko) | 2012-09-13 |
| RU2533833C2 (ru) | 2014-11-20 |
| JP5838164B2 (ja) | 2015-12-24 |
| ES2474515T3 (es) | 2014-07-09 |
| CA2784526A1 (en) | 2011-06-23 |
| US20150158887A1 (en) | 2015-06-11 |
| PL2513043T3 (pl) | 2014-08-29 |
| ZA201205192B (en) | 2013-03-27 |
| BR112012014621B8 (pt) | 2021-10-26 |
| PT2513043E (pt) | 2014-06-11 |
| EP2513043A1 (en) | 2012-10-24 |
| CN102712574B (zh) | 2014-10-22 |
| NZ600910A (en) | 2015-02-27 |
| AU2010332960B2 (en) | 2013-08-01 |
| AU2010332960A1 (en) | 2012-07-19 |
| BR112012014621B1 (pt) | 2021-10-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 14TH ANNIV.) - STANDARD Year of fee payment: 14 |
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| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20241206 |
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| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT Effective date: 20241206 Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20241206 |
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| MPN | Maintenance fee for patent paid |
Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 15TH ANNIV.) - STANDARD Year of fee payment: 15 |
|
| U00 | Fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED Effective date: 20251205 |
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| U11 | Full renewal or maintenance fee paid |
Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT PAID IN FULL Effective date: 20251205 |