BR112012014621A2 - processo para a preparação de compostos de quelato - Google Patents

processo para a preparação de compostos de quelato

Info

Publication number
BR112012014621A2
BR112012014621A2 BR112012014621A BR112012014621A BR112012014621A2 BR 112012014621 A2 BR112012014621 A2 BR 112012014621A2 BR 112012014621 A BR112012014621 A BR 112012014621A BR 112012014621 A BR112012014621 A BR 112012014621A BR 112012014621 A2 BR112012014621 A2 BR 112012014621A2
Authority
BR
Brazil
Prior art keywords
chelate compounds
preparation
present
preparing
chelating agent
Prior art date
Application number
BR112012014621A
Other languages
English (en)
Other versions
BR112012014621B8 (pt
BR112012014621B1 (pt
Inventor
Federico Crivellin
Frederico Maisano
Original Assignee
Bracco Imaging Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bracco Imaging Spa filed Critical Bracco Imaging Spa
Publication of BR112012014621A2 publication Critical patent/BR112012014621A2/pt
Publication of BR112012014621B1 publication Critical patent/BR112012014621B1/pt
Publication of BR112012014621B8 publication Critical patent/BR112012014621B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic System
    • C07F5/003—Compounds containing elements of Groups 3 or 13 of the Periodic System without C-Metal linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/16—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions not involving the amino or carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/38—Separation; Purification; Stabilisation; Use of additives
    • C07C227/40—Separation; Purification

Abstract

processo para preparação de compostos de quelato. a presente invenção baseia-se geralmente um processo para a prepsração de compostos de quelato, compreemde a interação seletiva emtre uma matriz sólida e um agente quelante. em mais detalhes, a presente invenção permite a preparação de compostos de quelato úteis como agentes de diagnóstico, em rendimentos elevados e de uma maneira confiável.
BR112012014621A 2009-12-16 2010-12-15 Processo para a preparação de compostos de quelato BR112012014621B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP09179438A EP2338874A1 (en) 2009-12-16 2009-12-16 Process for the preparation of chelated compounds
EP09179438.8 2009-12-16
PCT/EP2010/069715 WO2011073236A1 (en) 2009-12-16 2010-12-15 Process for the preparation of chelated compounds

Publications (3)

Publication Number Publication Date
BR112012014621A2 true BR112012014621A2 (pt) 2016-03-01
BR112012014621B1 BR112012014621B1 (pt) 2021-10-05
BR112012014621B8 BR112012014621B8 (pt) 2021-10-26

Family

ID=41800716

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012014621A BR112012014621B8 (pt) 2009-12-16 2010-12-15 Processo para a preparação de compostos de quelato

Country Status (19)

Country Link
US (2) US8987508B2 (pt)
EP (2) EP2338874A1 (pt)
JP (1) JP5838164B2 (pt)
KR (1) KR101766280B1 (pt)
CN (1) CN102712574B (pt)
AU (1) AU2010332960C1 (pt)
BR (1) BR112012014621B8 (pt)
CA (1) CA2784526C (pt)
ES (1) ES2474515T3 (pt)
HR (1) HRP20140430T1 (pt)
IL (1) IL220414A0 (pt)
MX (1) MX2012006954A (pt)
NZ (1) NZ600910A (pt)
PL (1) PL2513043T3 (pt)
PT (1) PT2513043E (pt)
RU (1) RU2533833C2 (pt)
SG (1) SG181776A1 (pt)
WO (1) WO2011073236A1 (pt)
ZA (1) ZA201205192B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9645132B2 (en) 2012-01-11 2017-05-09 Adelaide Research & Innovation Pty Ltd Stabilising and analysing fatty acids in a biological sample stored on solid media
CN102603550B (zh) * 2012-02-16 2014-11-26 佛山普正医药科技有限公司 一种中间体bopta的制备方法
CN103664672B (zh) * 2013-10-21 2016-01-13 河北一品制药有限公司 一种工业化生产钆喷酸葡胺的制备方法
US10696562B2 (en) * 2013-12-05 2020-06-30 Colorado School Of Mines Upgrade of yttrium in a mixed rare earth stream using iminodiacetic acid functionalized resin
EP2977369A1 (en) * 2014-07-24 2016-01-27 Bracco Imaging SPA Preparation of a solid form of gadobenate dimeglumine
GB201421162D0 (en) 2014-11-28 2015-01-14 Ge Healthcare As Lanthanide complex formulations
GB201421161D0 (en) * 2014-11-28 2015-01-14 Ge Healthcare As Metal complex formulations
CN109608350B (zh) * 2018-12-29 2021-06-22 湖北壮美生物科技有限公司 一种工业化制备甘氨酸钙的装置及相应的甘氨酸钙生产方法
WO2020159399A1 (ru) * 2019-01-31 2020-08-06 Акционерное Общество "Биоамид" Способ получения комплексной микроэлементной добавки в корма на основе органических соединений железа, марганца, цинка, меди, кобальта

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3172898A (en) * 1965-03-09 Process for preparation of metal chelates of aminopolycarboxylic acid compounds
SU138608A1 (ru) 1960-07-14 1960-11-30 Т.В. Лищенко Способ получени алюминиевой соли этилендиаминтетрауксусной кислоты
NL194579C (nl) * 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
EP0173484B1 (en) * 1984-08-06 1990-11-28 Westinghouse Electric Corporation Process for the separation of gadelinium isotopes
US4711768A (en) * 1984-08-06 1987-12-08 Westinghouse Electric Corp. Process for the separation of gadolinium isotopes
IT1213029B (it) 1986-01-30 1989-12-07 Bracco Ind Chimica Spa Chelati di ioni metallici paramagnetici.
DE3922005A1 (de) * 1989-06-30 1991-01-10 Schering Ag Derivatisierte dtpa-komplexe, diese verbindungen enthaltende pharmazeutische mittel, ihre verwendung und verfahren zu deren herstellung
AU625529B2 (en) * 1989-12-22 1992-07-16 E.R. Squibb & Sons, Inc. 10-(2'-hydroxy-3'-alkoxy-1,4,7-triscarboxymethyl-1,4,7,10- tetraazacyclododecanes
US5262018A (en) * 1991-08-12 1993-11-16 Fmc Corporation Metals removal from aqueous peroxy acids or peroxy salts
IT1269839B (it) * 1994-05-26 1997-04-15 Bracco Spa Coniugati di acidi biliari, loro derivati con complessi metallici e relativi usi
IT1283218B1 (it) * 1996-03-08 1998-04-16 Bracco Spa Polichelanti, loro complessi con ioni metallici, loro preparazione e loro usi
GB9707880D0 (en) * 1997-04-18 1997-06-04 Nycomed Imaging As Contrast agent preparation
ITMI981583A1 (it) * 1998-07-10 2000-01-10 Bracco Spa Processo per la preparazione dell'acido 4 -carbossi-5,8,11-tris (carbossimetil)-1-fenil-2-oxa-5,8,11-triazatridecan-13-oico
US6342598B1 (en) * 1998-11-26 2002-01-29 Bracco International B.V. Amphipatic polycarboxylic chelates and complexes with paramagnetic metals as MRI contrast agents
EP1762563A1 (en) 2005-09-13 2007-03-14 BRACCO IMAGING S.p.A. Process for the preparation of contrast agents
US20090208421A1 (en) 2008-02-19 2009-08-20 Dominique Meyer Process for preparing a pharmaceutical formulation of contrast agents

Also Published As

Publication number Publication date
PT2513043E (pt) 2014-06-11
CN102712574A (zh) 2012-10-03
AU2010332960B2 (en) 2013-08-01
AU2010332960C1 (en) 2014-01-23
EP2513043A1 (en) 2012-10-24
CN102712574B (zh) 2014-10-22
AU2010332960A1 (en) 2012-07-19
HRP20140430T1 (hr) 2014-07-18
WO2011073236A1 (en) 2011-06-23
EP2338874A1 (en) 2011-06-29
RU2012129982A (ru) 2014-01-27
CA2784526C (en) 2014-09-30
RU2533833C2 (ru) 2014-11-20
SG181776A1 (en) 2012-07-30
IL220414A0 (en) 2012-08-30
ES2474515T3 (es) 2014-07-09
PL2513043T3 (pl) 2014-08-29
US9567350B2 (en) 2017-02-14
JP5838164B2 (ja) 2015-12-24
US20150158887A1 (en) 2015-06-11
BR112012014621B8 (pt) 2021-10-26
NZ600910A (en) 2015-02-27
US8987508B2 (en) 2015-03-24
ZA201205192B (en) 2013-03-27
CA2784526A1 (en) 2011-06-23
EP2513043B1 (en) 2014-03-26
KR101766280B1 (ko) 2017-08-08
KR20120101525A (ko) 2012-09-13
JP2013514311A (ja) 2013-04-25
BR112012014621B1 (pt) 2021-10-05
US20120245333A1 (en) 2012-09-27
MX2012006954A (es) 2012-07-30

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Legal Events

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B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]

Free format text: DE ACORDO COM O ARTIGO 229-C DA LEI NO 10196/2001, QUE MODIFICOU A LEI NO 9279/96, A CONCESSAO DA PATENTE ESTA CONDICIONADA A ANUENCIA PREVIA DA ANVISA. CONSIDERANDO A APROVACAO DOS TERMOS DO PARECER NO 337/PGF/EA/2010, BEM COMO A PORTARIA INTERMINISTERIAL NO 1065 DE 24/05/2012, ENCAMINHA-SE O PRESENTE PEDIDO PARA AS PROVIDENCIAS CABIVEIS.

B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 15/12/2010, OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF, QUE DETERMINA A ALTERACAO DO PRAZO DE CONCESSAO.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: REF. RPI 2648 DE 05/10/2021 QUANTO AO INVENTOR (ITEM 72).