CA2759070C - Procede pour la production de derive de chaine de sucre, procede d'analyse de structure, et derive de chaine de sucre - Google Patents

Procede pour la production de derive de chaine de sucre, procede d'analyse de structure, et derive de chaine de sucre Download PDF

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Publication number
CA2759070C
CA2759070C CA2759070A CA2759070A CA2759070C CA 2759070 C CA2759070 C CA 2759070C CA 2759070 A CA2759070 A CA 2759070A CA 2759070 A CA2759070 A CA 2759070A CA 2759070 C CA2759070 C CA 2759070C
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CA
Canada
Prior art keywords
4g1cnac
man
oligosaccharide
mixture
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2759070A
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English (en)
Other versions
CA2759070A1 (fr
Inventor
Kazuaki Kakehi
Mitsuhiro Kinoshita
Yuki Matsuno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glytech Inc
Original Assignee
Glytech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glytech Inc filed Critical Glytech Inc
Publication of CA2759070A1 publication Critical patent/CA2759070A1/fr
Application granted granted Critical
Publication of CA2759070C publication Critical patent/CA2759070C/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/84—Preparation of the fraction to be distributed
    • G01N2030/8429—Preparation of the fraction to be distributed adding modificating material
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Materials Engineering (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

Ci-après un procédé de production d'un dérivé d'oligosaccharides à partir d'un mélange d'oligosaccharides. Ce procédé est caractérisé par le fait qu'il comporte une étape (a) d'introduction d'un groupe lipophile dans les oligosaccharides du mélange pour obtenir un mélange de dérivés d'oligosaccharides, et une étape (b) de traitement du mélange dérivé d'oligosaccharides par chromatographie en colonne par affinité à la sérotonine.
CA2759070A 2005-07-19 2006-07-19 Procede pour la production de derive de chaine de sucre, procede d'analyse de structure, et derive de chaine de sucre Expired - Fee Related CA2759070C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2005-209077 2005-07-19
JP2005209077 2005-07-19
CA2616065A CA2616065C (fr) 2005-07-19 2006-07-19 Procede pour la production de derive de chaine de sucre, procede d'analyse de structure, et derive de chaine de sucre

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2616065A Division CA2616065C (fr) 2005-07-19 2006-07-19 Procede pour la production de derive de chaine de sucre, procede d'analyse de structure, et derive de chaine de sucre

Publications (2)

Publication Number Publication Date
CA2759070A1 CA2759070A1 (fr) 2007-01-25
CA2759070C true CA2759070C (fr) 2013-09-24

Family

ID=37668925

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2759070A Expired - Fee Related CA2759070C (fr) 2005-07-19 2006-07-19 Procede pour la production de derive de chaine de sucre, procede d'analyse de structure, et derive de chaine de sucre
CA2616065A Expired - Fee Related CA2616065C (fr) 2005-07-19 2006-07-19 Procede pour la production de derive de chaine de sucre, procede d'analyse de structure, et derive de chaine de sucre

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2616065A Expired - Fee Related CA2616065C (fr) 2005-07-19 2006-07-19 Procede pour la production de derive de chaine de sucre, procede d'analyse de structure, et derive de chaine de sucre

Country Status (10)

Country Link
US (2) US8318694B2 (fr)
EP (1) EP1908783B1 (fr)
JP (2) JP5011108B2 (fr)
KR (3) KR101001433B1 (fr)
CN (3) CN101949901B (fr)
AU (2) AU2006270732B2 (fr)
CA (2) CA2759070C (fr)
SG (1) SG149832A1 (fr)
TW (2) TWI342880B (fr)
WO (1) WO2007011055A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5004464B2 (ja) * 2005-12-02 2012-08-22 大塚化学株式会社 糖鎖修飾リポソーム
JP2007297429A (ja) * 2006-04-27 2007-11-15 Institute Of Physical & Chemical Research 糖鎖ライブラリの作製方法及びその利用
WO2008096790A1 (fr) * 2007-02-07 2008-08-14 Galpharma Co., Ltd. Analyse et utilisation d'une chaîne de sucre en tant que marqueur de tumeur
CN101796064B (zh) 2007-07-31 2014-04-16 株式会社糖锁工学研究所 肽的制备方法
CA2727147A1 (fr) 2008-06-17 2009-12-23 Otsuka Chemical Co., Ltd. Peptide glp-1 glycosyle
CN102124024A (zh) 2008-08-19 2011-07-13 大塚化学株式会社 糖蛋白质的制造方法以及筛选方法
JP2012063140A (ja) * 2008-12-15 2012-03-29 Hokkaido Univ 糖鎖分析による肺がんの診断方法
TW201031749A (en) 2009-02-10 2010-09-01 Otsuka Chemical Co Ltd IgG-Fc fragment and method for manufacturing the same
US20120114595A1 (en) 2009-07-16 2012-05-10 Otsuka Chemical Co., Ltd. Sugar chain-added ailim extracellular domain and method for producing same
JPWO2011052523A1 (ja) 2009-10-30 2013-03-21 株式会社糖鎖工学研究所 抗原性ｇｌｐ−１アナログの糖鎖付加体
US8801924B2 (en) * 2010-07-07 2014-08-12 Ironstone Separations, Inc. Chromatography methods
CA2847336C (fr) 2011-09-04 2021-09-07 Glytech, Inc. Polypeptide glycosyle et composition medicamenteuse contenant ce polypeptide
DK2752424T3 (da) 2011-09-04 2019-11-18 Glytech Inc Glycosyleret somatostatin og lægemiddelsammensætning, der indeholder det
KR102227918B1 (ko) 2012-11-22 2021-03-15 가부시키가이샤 도우사 고가쿠 겐큐쇼 당쇄 부가 링커, 당쇄 부가 링커 부분과 생리 활성 물질 부분을 함유하는 화합물 또는 그의 염, 및 이들의 제조 방법
JP6219308B2 (ja) 2012-11-30 2017-10-25 株式会社糖鎖工学研究所 糖鎖付加リンカー、糖鎖付加リンカーと生理活性物質とを含む化合物またはその塩、及びそれらの製造方法
RU2664539C2 (ru) 2013-03-30 2018-08-20 Глитек, Инк. Комплексы типа сахаридная цепочка-полипептид
CA3228982A1 (fr) 2014-07-09 2016-01-14 Dsm Nutritional Products, Llc Compositions d'oligosaccharides et leurs procedes de production
JP6722697B2 (ja) 2015-01-26 2020-07-15 カデナ・バイオ・インコーポレイテッド 動物飼料として使用するためのオリゴ糖組成物及びその生成方法
CA2991013C (fr) * 2015-06-30 2023-09-26 Glytech, Inc. Complexe d'albumine-chaine de sucre
DK179801B1 (en) * 2017-12-17 2019-06-26 Upfront Chromatography A/S SEPARATION OF OLIGOSACCHARIDES

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936102A (ja) * 1982-08-24 1984-02-28 Seikagaku Kogyo Co Ltd シアル酸又はシアル酸含有物質の分離・精製法
JP3495378B2 (ja) * 1991-01-25 2004-02-09 中外製薬株式会社 カゼイノグリコペプチドの製造及び精製方法
FR2780901B1 (fr) * 1998-07-09 2000-09-29 Coletica Particules, en particulier micro- ou nanoparticules de monosaccharides et oligosaccharides reticules, leurs procedes de preparation et compositions cosmetiques, pharmaceutiques ou alimentaires en contenant
DE19860376A1 (de) * 1998-12-28 2000-07-06 Aventis Res & Tech Gmbh & Co Alpha-1,4 Glucanketten enthaltende Polysaccharide sowie Verfahren zu ihrer Herstellung
JP4243898B2 (ja) * 1999-10-19 2009-03-25 ノーリツ鋼機株式会社 証明写真処理システム
US6441293B1 (en) * 2000-04-28 2002-08-27 Labarbera Anthony System for generating percussion sounds from stringed instruments
CA2451971C (fr) * 2001-06-19 2010-09-07 Otsuka Chemical Co., Ltd. Methode de production d'un derive d'asparagine de chaines des sucres
TWI330641B (en) * 2002-12-24 2010-09-21 Yasuhiro Kajihara Sugar chain asparagine derivatives
JP4495598B2 (ja) * 2002-12-26 2010-07-07 康宏 梶原 糖鎖アスパラギン誘導体およびその製造方法
US20070167608A1 (en) * 2003-12-25 2007-07-19 Jun Hirabayashi Sugar chain structure profiling techniques

Also Published As

Publication number Publication date
CN101949901A (zh) 2011-01-19
CA2616065C (fr) 2012-02-07
TW200730541A (en) 2007-08-16
US20130074585A1 (en) 2013-03-28
AU2010202058C1 (en) 2012-07-26
TWI466897B (zh) 2015-01-01
JP5688043B2 (ja) 2015-03-25
KR101001489B1 (ko) 2010-12-14
KR20100092042A (ko) 2010-08-19
KR20080028994A (ko) 2008-04-02
CN102516402A (zh) 2012-06-27
JP5011108B2 (ja) 2012-08-29
CN101223194B (zh) 2011-04-13
KR101001433B1 (ko) 2010-12-14
EP1908783B1 (fr) 2016-06-08
JP2012162542A (ja) 2012-08-30
EP1908783A4 (fr) 2009-12-02
US20090215100A1 (en) 2009-08-27
CN101223194A (zh) 2008-07-16
AU2006270732A1 (en) 2007-01-25
KR100968691B1 (ko) 2010-07-06
AU2010202058A1 (en) 2010-06-10
SG149832A1 (en) 2009-02-27
CA2759070A1 (fr) 2007-01-25
TWI342880B (en) 2011-06-01
KR20100029154A (ko) 2010-03-15
JPWO2007011055A1 (ja) 2009-02-05
WO2007011055A1 (fr) 2007-01-25
US8318694B2 (en) 2012-11-27
US8691795B2 (en) 2014-04-08
AU2006270732B2 (en) 2010-06-24
CA2616065A1 (fr) 2007-01-25
EP1908783A1 (fr) 2008-04-09
AU2010202058B2 (en) 2011-10-06
CN101949901B (zh) 2013-07-17
TW201124428A (en) 2011-07-16

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Effective date: 20220301

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Effective date: 20200831