CA2728574C - Cancer diagnosis based on levels of antibodies against globo h and its fragments - Google Patents

Cancer diagnosis based on levels of antibodies against globo h and its fragments Download PDF

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Publication number
CA2728574C
CA2728574C CA2728574A CA2728574A CA2728574C CA 2728574 C CA2728574 C CA 2728574C CA 2728574 A CA2728574 A CA 2728574A CA 2728574 A CA2728574 A CA 2728574A CA 2728574 C CA2728574 C CA 2728574C
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cancer
globo
sample
antibodies
mixing
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CA2728574A
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English (en)
French (fr)
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CA2728574A1 (en
Inventor
Chi-Huey Wong
Chung-Yi Wu
Cheng-Chi Wang
Alice L. Yu
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Academia Sinica
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Academia Sinica
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/57585—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds identifiable in body fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57515—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the breast

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
CA2728574A 2008-06-16 2009-06-16 Cancer diagnosis based on levels of antibodies against globo h and its fragments Active CA2728574C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US6197408P 2008-06-16 2008-06-16
US61/061,974 2008-06-16
PCT/US2009/047532 WO2010008736A2 (en) 2008-06-16 2009-06-16 Cancer diagnosis based on levels of antibodies against globo h and its fragments

Publications (2)

Publication Number Publication Date
CA2728574A1 CA2728574A1 (en) 2010-01-21
CA2728574C true CA2728574C (en) 2020-10-20

Family

ID=41431641

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2728574A Active CA2728574C (en) 2008-06-16 2009-06-16 Cancer diagnosis based on levels of antibodies against globo h and its fragments

Country Status (11)

Country Link
US (1) US8158367B2 (enExample)
EP (1) EP2307887B1 (enExample)
JP (1) JP5216139B2 (enExample)
KR (1) KR101324109B1 (enExample)
CN (1) CN102066940B (enExample)
AU (1) AU2009271411B2 (enExample)
CA (1) CA2728574C (enExample)
ES (1) ES2477549T3 (enExample)
MX (1) MX2010013931A (enExample)
NZ (1) NZ590064A (enExample)
WO (1) WO2010008736A2 (enExample)

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US7960139B2 (en) 2007-03-23 2011-06-14 Academia Sinica Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
JP5986745B2 (ja) 2008-07-15 2016-09-06 アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ Ｐｔｆｅ様のアルミニウム・コート・ガラススライド上のグリカンアレイおよび関連する方法
US10087236B2 (en) 2009-12-02 2018-10-02 Academia Sinica Methods for modifying human antibodies by glycan engineering
US11377485B2 (en) 2009-12-02 2022-07-05 Academia Sinica Methods for modifying human antibodies by glycan engineering
US8957107B2 (en) 2009-12-15 2015-02-17 The Hospital For Sick Children Method of treating scars and β-catenin-mediated disorders using Nefopam compounds
WO2011130332A1 (en) 2010-04-12 2011-10-20 Academia Sinica Glycan arrays for high throughput screening of viruses
US10132817B2 (en) 2011-07-12 2018-11-20 Rowan University Diagnostic biomarker profiles for the detection and diagnosis of alzheimer's disease
US10130714B2 (en) 2012-04-14 2018-11-20 Academia Sinica Enhanced anti-influenza agents conjugated with anti-inflammatory activity
WO2014018903A1 (en) * 2012-07-27 2014-01-30 Rowan University Autoantibody profiles in early detection and diagnosis of cancer
WO2014031498A1 (en) 2012-08-18 2014-02-27 Academia Sinica Cell-permeable probes for identification and imaging of sialidases
US10086054B2 (en) 2013-06-26 2018-10-02 Academia Sinica RM2 antigens and use thereof
WO2014210564A1 (en) 2013-06-27 2014-12-31 Academia Sinica Glycan conjugates and use thereof
JP6486368B2 (ja) 2013-09-06 2019-03-20 アカデミア シニカＡｃａｄｅｍｉａ Ｓｉｎｉｃａ 改変されたグリコシル基を含む糖脂質を用いたヒトｉＮＫＴ細胞の活性化
CN104698183A (zh) * 2013-12-04 2015-06-10 苏州中赢医疗科技有限公司 一种肝癌肿瘤标志物、其抗体及应用
US10150818B2 (en) 2014-01-16 2018-12-11 Academia Sinica Compositions and methods for treatment and detection of cancers
TW201620939A (zh) 2014-01-16 2016-06-16 中央研究院 治療及檢測癌症之組合物及方法
MX2016012124A (es) 2014-03-19 2017-04-06 Mackay Medical Found The Presbyterian Church In Taiwan Mackay Memorial Hospital Anticuerpos contra glicopeptidos inmunogenicos, composicion que los comprende y usos de estos.
EP3129767B1 (en) 2014-03-27 2021-09-01 Academia Sinica Reactive labelling compounds and uses thereof
CA3104268A1 (en) 2014-04-10 2015-10-15 Obi Pharma Inc. Antibodies, pharmaceutical compositions and uses thereof
KR20170003720A (ko) 2014-05-27 2017-01-09 아카데미아 시니카 항-ｃｄ20 글리코항체 및 이의 용도
US10118969B2 (en) 2014-05-27 2018-11-06 Academia Sinica Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
AU2015267045B2 (en) 2014-05-27 2021-02-25 Academia Sinica Anti-HER2 glycoantibodies and uses thereof
DK3149045T3 (da) 2014-05-27 2023-03-06 Academia Sinica Sammensætninger og fremgangsmåder vedrørende universelle glycoformer til forbedret antistofeffekt
JP7063538B2 (ja) 2014-05-28 2022-05-09 アカデミア シニカ 抗ＴＮＦα糖操作抗体群およびその使用
EP3191500A4 (en) 2014-09-08 2018-04-11 Academia Sinica HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS
US10495645B2 (en) 2015-01-16 2019-12-03 Academia Sinica Cancer markers and methods of use thereof
US9975965B2 (en) 2015-01-16 2018-05-22 Academia Sinica Compositions and methods for treatment and detection of cancers
KR102630294B1 (ko) 2015-01-24 2024-01-26 아카데미아 시니카 암 마커 및 이를 사용하는 방법
US10342858B2 (en) 2015-01-24 2019-07-09 Academia Sinica Glycan conjugates and methods of use thereof
TWI717333B (zh) 2015-01-30 2021-02-01 中央研究院 增進抗體功效之通用糖型組合物及方法
JP6822957B2 (ja) * 2015-07-30 2021-01-27 京セラ株式会社 測定方法、および測定装置
JP2018532990A (ja) * 2015-09-04 2018-11-08 オービーアイ ファーマ，インコーポレイテッド グリカンアレイおよび使用の方法
AU2017231749A1 (en) 2016-03-08 2018-09-20 Academia Sinica Methods for modular synthesis of N-glycans and arrays thereof
EP3491026A4 (en) * 2016-07-29 2020-07-29 OBI Pharma, Inc. HUMAN ANTIBODIES, PHARMACEUTICAL COMPOSITIONS AND PROCESSES
AU2017316663B2 (en) 2016-08-22 2024-02-22 CHO Pharma Inc. Antibodies, binding fragments, and methods of use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0996455B1 (en) 1997-04-16 2009-12-16 Sloan-Kettering Institute For Cancer Research Alpha-o-linked glycoconjugates with clustered (2,6)-st epitopes, methods of preparation and uses thereof
CN1235831A (zh) * 1999-03-02 1999-11-24 第一军医大学珠江医院 含红细胞糖苷脂的药物组合物及其应用
US20020006629A1 (en) * 2000-02-29 2002-01-17 Danishefsky Samuel J. Affinity matrix bearing tumor-associated carbohydrate-or glycopeptide-based antigens and uses thereof
WO2006068758A2 (en) 2004-11-19 2006-06-29 The Scripps Research Institute Detection, prevention and treatment of breast cancer
US20060269979A1 (en) * 2005-04-26 2006-11-30 Dwek Raymond A High throughput glycan analysis for diagnosing and monitoring rheumatoid arthritis and other autoimmune diseases
US20090162405A1 (en) * 2006-12-14 2009-06-25 Yong Qian Proteinase-engineered cancer vaccine induces immune responses to prevent cancer and to systemically kill cancer cells
JP2011524375A (ja) * 2008-06-16 2011-09-01 アカデミア シニカ ＧｌｏｂｏＨおよびＳＳＥＡ３に特異的な免疫反応を誘起する組成物および癌治療におけるその使用

Also Published As

Publication number Publication date
AU2009271411A1 (en) 2010-01-21
AU2009271411B2 (en) 2013-02-07
EP2307887A2 (en) 2011-04-13
MX2010013931A (es) 2011-06-01
JP5216139B2 (ja) 2013-06-19
US8158367B2 (en) 2012-04-17
KR20110033919A (ko) 2011-04-01
NZ590064A (en) 2012-05-25
CN102066940A (zh) 2011-05-18
WO2010008736A2 (en) 2010-01-21
EP2307887A4 (en) 2011-09-21
EP2307887B1 (en) 2014-05-07
CA2728574A1 (en) 2010-01-21
WO2010008736A3 (en) 2010-03-11
HK1153273A1 (en) 2012-03-23
ES2477549T3 (es) 2014-07-17
KR101324109B1 (ko) 2013-10-31
JP2011524537A (ja) 2011-09-01
US20090317837A1 (en) 2009-12-24
CN102066940B (zh) 2015-05-13

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