ES2477549T3 - Diagnóstico del cáncer según la concentración de anticuerpos contra Globo H y sus fragmentos - Google Patents
Diagnóstico del cáncer según la concentración de anticuerpos contra Globo H y sus fragmentos Download PDFInfo
- Publication number
- ES2477549T3 ES2477549T3 ES09798419.9T ES09798419T ES2477549T3 ES 2477549 T3 ES2477549 T3 ES 2477549T3 ES 09798419 T ES09798419 T ES 09798419T ES 2477549 T3 ES2477549 T3 ES 2477549T3
- Authority
- ES
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- Prior art keywords
- cancer
- antibodies
- sample
- globo
- globe
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
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- NHBKXEKEPDILRR-UHFFFAOYSA-N 2,3-bis(butanoylsulfanyl)propyl butanoate Chemical compound CCCC(=O)OCC(SC(=O)CCC)CSC(=O)CCC NHBKXEKEPDILRR-UHFFFAOYSA-N 0.000 description 1
- 102000002068 Glycopeptides Human genes 0.000 description 1
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- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
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- 208000035269 cancer or benign tumor Diseases 0.000 description 1
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- 150000004676 glycans Chemical class 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57415—Specifically defined cancers of breast
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6197408P | 2008-06-16 | 2008-06-16 | |
| US61974P | 2008-06-16 | ||
| PCT/US2009/047532 WO2010008736A2 (en) | 2008-06-16 | 2009-06-16 | Cancer diagnosis based on levels of antibodies against globo h and its fragments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES2477549T3 true ES2477549T3 (es) | 2014-07-17 |
Family
ID=41431641
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES09798419.9T Active ES2477549T3 (es) | 2008-06-16 | 2009-06-16 | Diagnóstico del cáncer según la concentración de anticuerpos contra Globo H y sus fragmentos |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8158367B2 (enExample) |
| EP (1) | EP2307887B1 (enExample) |
| JP (1) | JP5216139B2 (enExample) |
| KR (1) | KR101324109B1 (enExample) |
| CN (1) | CN102066940B (enExample) |
| AU (1) | AU2009271411B2 (enExample) |
| CA (1) | CA2728574C (enExample) |
| ES (1) | ES2477549T3 (enExample) |
| MX (1) | MX2010013931A (enExample) |
| NZ (1) | NZ590064A (enExample) |
| WO (1) | WO2010008736A2 (enExample) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
| US8680020B2 (en) | 2008-07-15 | 2014-03-25 | Academia Sinica | Glycan arrays on PTFE-like aluminum coated glass slides and related methods |
| US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
| ES2594900T3 (es) | 2009-12-15 | 2016-12-23 | The Hospital For Sick Children | Método para tratar cicatrices y trastornos mediados por beta-catenina |
| US10338069B2 (en) | 2010-04-12 | 2019-07-02 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
| WO2013010003A1 (en) | 2011-07-12 | 2013-01-17 | University Of Medicine And Dentistry Of New Jersey | Diagnostic biomarker profiles for the detection and diagnosis of alzheimer's disease |
| US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
| US20150198600A1 (en) * | 2012-07-27 | 2015-07-16 | Rowan University | Autoantibody Profiles in the Early Detection and Diagnosis of Cancer |
| EP2885311B1 (en) | 2012-08-18 | 2020-01-01 | Academia Sinica | Cell-permeable probes for identification and imaging of sialidases |
| EP3013365B1 (en) | 2013-06-26 | 2019-06-05 | Academia Sinica | Rm2 antigens and use thereof |
| US9981030B2 (en) | 2013-06-27 | 2018-05-29 | Academia Sinica | Glycan conjugates and use thereof |
| KR102298172B1 (ko) | 2013-09-06 | 2021-09-06 | 아카데미아 시니카 | 변화된 글리코실 그룹을 갖는 당지질을 사용한 인간 iNKT 세포 활성화 |
| CN104698183A (zh) * | 2013-12-04 | 2015-06-10 | 苏州中赢医疗科技有限公司 | 一种肝癌肿瘤标志物、其抗体及应用 |
| US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| KR20160104727A (ko) | 2014-01-16 | 2016-09-05 | 아카데미아 시니카 | 암의 치료 및 검출을 위한 조성물 및 방법 |
| WO2015143126A1 (en) | 2014-03-19 | 2015-09-24 | Mackay Memorial Hospital Of Taiwan Presbyterian Church And Mackay Memorial Social Work Foundation | Immunogenic glycopeptides, composition comprising the glycopeptides and use thereof |
| TWI797430B (zh) | 2014-03-27 | 2023-04-01 | 中央研究院 | 反應性標記化合物及其用途 |
| SG11201607258SA (en) | 2014-04-10 | 2016-10-28 | Obi Pharma Inc | Antibodies, pharmaceutical compositions and uses thereof |
| AU2015267052A1 (en) | 2014-05-27 | 2016-12-15 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
| KR20240096599A (ko) | 2014-05-27 | 2024-06-26 | 아카데미아 시니카 | 항-ｃｄ20 글리코항체 및 이의 용도 |
| US10005847B2 (en) | 2014-05-27 | 2018-06-26 | Academia Sinica | Anti-HER2 glycoantibodies and uses thereof |
| JP7063538B2 (ja) | 2014-05-28 | 2022-05-09 | アカデミア シニカ | 抗ＴＮＦα糖操作抗体群およびその使用 |
| CN107001404B (zh) | 2014-09-08 | 2021-06-29 | 中央研究院 | 使用醣脂激活人类iNKT细胞 |
| US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
| US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
| CN107430127B (zh) | 2015-01-24 | 2020-08-28 | 中央研究院 | 癌症标记及其使用方法 |
| TWI736523B (zh) | 2015-01-24 | 2021-08-21 | 中央研究院 | 新穎聚醣結合物及其使用方法 |
| TWI717333B (zh) | 2015-01-30 | 2021-02-01 | 中央研究院 | 增進抗體功效之通用糖型組合物及方法 |
| WO2017018049A1 (ja) * | 2015-07-30 | 2017-02-02 | 京セラ株式会社 | 測定方法、および測定装置 |
| JP2018532990A (ja) * | 2015-09-04 | 2018-11-08 | オービーアイ ファーマ，インコーポレイテッド | グリカンアレイおよび使用の方法 |
| CA3016170A1 (en) | 2016-03-08 | 2017-09-14 | Academia Sinica | Methods for modular synthesis of n-glycans and arrays thereof |
| US11643456B2 (en) * | 2016-07-29 | 2023-05-09 | Obi Pharma, Inc. | Human antibodies, pharmaceutical compositions and methods |
| AU2017316663B2 (en) | 2016-08-22 | 2024-02-22 | CHO Pharma Inc. | Antibodies, binding fragments, and methods of use |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU750701C (en) | 1997-04-16 | 2003-03-20 | Sloan-Kettering Institute For Cancer Research | Alpha-O-linked glycoconjugates, methods of preparation and uses thereof |
| CN1235831A (zh) * | 1999-03-02 | 1999-11-24 | 第一军医大学珠江医院 | 含红细胞糖苷脂的药物组合物及其应用 |
| WO2001065261A1 (en) * | 2000-02-29 | 2001-09-07 | Sloan-Kettering Institute For Cancer Research | Affinity matrix bearing tumor-associated antigens |
| WO2006068758A2 (en) * | 2004-11-19 | 2006-06-29 | The Scripps Research Institute | Detection, prevention and treatment of breast cancer |
| US20060269979A1 (en) * | 2005-04-26 | 2006-11-30 | Dwek Raymond A | High throughput glycan analysis for diagnosing and monitoring rheumatoid arthritis and other autoimmune diseases |
| US20090162405A1 (en) * | 2006-12-14 | 2009-06-25 | Yong Qian | Proteinase-engineered cancer vaccine induces immune responses to prevent cancer and to systemically kill cancer cells |
| CA2728344A1 (en) * | 2008-06-16 | 2010-01-14 | Academia Sinica | Compositions for inducing immune responses specific to globo h and ssea3 and uses thereof in cancer treatment |
-
2009
- 2009-06-16 MX MX2010013931A patent/MX2010013931A/es active IP Right Grant
- 2009-06-16 EP EP09798419.9A patent/EP2307887B1/en active Active
- 2009-06-16 CN CN200980123715.3A patent/CN102066940B/zh active Active
- 2009-06-16 AU AU2009271411A patent/AU2009271411B2/en active Active
- 2009-06-16 JP JP2011514757A patent/JP5216139B2/ja active Active
- 2009-06-16 CA CA2728574A patent/CA2728574C/en active Active
- 2009-06-16 NZ NZ590064A patent/NZ590064A/en unknown
- 2009-06-16 ES ES09798419.9T patent/ES2477549T3/es active Active
- 2009-06-16 US US12/485,516 patent/US8158367B2/en active Active
- 2009-06-16 KR KR1020117000783A patent/KR101324109B1/ko active Active
- 2009-06-16 WO PCT/US2009/047532 patent/WO2010008736A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP5216139B2 (ja) | 2013-06-19 |
| CN102066940A (zh) | 2011-05-18 |
| CA2728574C (en) | 2020-10-20 |
| NZ590064A (en) | 2012-05-25 |
| AU2009271411B2 (en) | 2013-02-07 |
| WO2010008736A2 (en) | 2010-01-21 |
| US8158367B2 (en) | 2012-04-17 |
| EP2307887B1 (en) | 2014-05-07 |
| CA2728574A1 (en) | 2010-01-21 |
| KR20110033919A (ko) | 2011-04-01 |
| KR101324109B1 (ko) | 2013-10-31 |
| MX2010013931A (es) | 2011-06-01 |
| AU2009271411A1 (en) | 2010-01-21 |
| US20090317837A1 (en) | 2009-12-24 |
| JP2011524537A (ja) | 2011-09-01 |
| WO2010008736A3 (en) | 2010-03-11 |
| CN102066940B (zh) | 2015-05-13 |
| EP2307887A4 (en) | 2011-09-21 |
| HK1153273A1 (en) | 2012-03-23 |
| EP2307887A2 (en) | 2011-04-13 |
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