CA2698545C - Copy number variation determination, methods and systems - Google Patents

Copy number variation determination, methods and systems Download PDF

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Publication number
CA2698545C
CA2698545C CA2698545A CA2698545A CA2698545C CA 2698545 C CA2698545 C CA 2698545C CA 2698545 A CA2698545 A CA 2698545A CA 2698545 A CA2698545 A CA 2698545A CA 2698545 C CA2698545 C CA 2698545C
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Canada
Prior art keywords
polynucleotide sequence
sample
amplification
target polynucleotide
reaction
Prior art date
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Expired - Fee Related
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CA2698545A
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English (en)
French (fr)
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CA2698545A1 (en
Inventor
Ramesh Ramakrishnan
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Standard Biotools Inc
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Fluidigm Corp
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6851—Quantitative amplification
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Eye Examination Apparatus (AREA)
  • Inert Electrodes (AREA)
  • Control Of Vending Devices And Auxiliary Devices For Vending Devices (AREA)
CA2698545A 2007-09-07 2008-09-08 Copy number variation determination, methods and systems Expired - Fee Related CA2698545C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96789707P 2007-09-07 2007-09-07
US60/967,897 2007-09-07
PCT/US2008/075636 WO2009033178A1 (en) 2007-09-07 2008-09-08 Copy number variation determination, methods and systems

Publications (2)

Publication Number Publication Date
CA2698545A1 CA2698545A1 (en) 2009-03-12
CA2698545C true CA2698545C (en) 2014-07-08

Family

ID=40429425

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2698545A Expired - Fee Related CA2698545C (en) 2007-09-07 2008-09-08 Copy number variation determination, methods and systems

Country Status (14)

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US (3) US8148078B2 (enExample)
EP (1) EP2198293B1 (enExample)
JP (1) JP5707132B2 (enExample)
KR (1) KR101518085B1 (enExample)
CN (1) CN101821619B (enExample)
AT (1) ATE541946T1 (enExample)
AU (1) AU2008295992B2 (enExample)
BR (1) BRPI0816393A2 (enExample)
CA (1) CA2698545C (enExample)
EA (1) EA018555B1 (enExample)
ES (1) ES2380844T3 (enExample)
IL (1) IL204288A (enExample)
MX (1) MX2010002556A (enExample)
WO (1) WO2009033178A1 (enExample)

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* Cited by examiner, † Cited by third party
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