CA2695734C - Use of interleukin-22 in the treatment of fatty liver disease - Google Patents

Use of interleukin-22 in the treatment of fatty liver disease Download PDF

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Publication number
CA2695734C
CA2695734C CA2695734A CA2695734A CA2695734C CA 2695734 C CA2695734 C CA 2695734C CA 2695734 A CA2695734 A CA 2695734A CA 2695734 A CA2695734 A CA 2695734A CA 2695734 C CA2695734 C CA 2695734C
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Prior art keywords
fatty liver
cells
liver
liver disease
gene
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CA2695734A
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English (en)
French (fr)
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CA2695734A1 (en
Inventor
Yu Liang Huang
Zhi Hua Huang
Qi Sun
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Evive Biotechnology Shanghai Ltd
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Generon Shanghai Corp Ltd
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Publication of CA2695734A1 publication Critical patent/CA2695734A1/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CA2695734A 2007-08-06 2008-08-01 Use of interleukin-22 in the treatment of fatty liver disease Active CA2695734C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CNCN200710044592.7 2007-08-06
CN2007100445927A CN101361968B (zh) 2007-08-06 2007-08-06 白介素-22在治疗脂肪肝中的应用
PCT/US2008/071859 WO2009020844A1 (en) 2007-08-06 2008-08-01 Use of interleukin-22 in the treatment of fatty liver disease

Publications (2)

Publication Number Publication Date
CA2695734A1 CA2695734A1 (en) 2009-02-12
CA2695734C true CA2695734C (en) 2017-02-14

Family

ID=40341656

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2695734A Active CA2695734C (en) 2007-08-06 2008-08-01 Use of interleukin-22 in the treatment of fatty liver disease

Country Status (7)

Country Link
US (3) US20110262385A1 (cg-RX-API-DMAC7.html)
EP (1) EP2185202B1 (cg-RX-API-DMAC7.html)
JP (1) JP5546453B2 (cg-RX-API-DMAC7.html)
CN (1) CN101361968B (cg-RX-API-DMAC7.html)
AU (1) AU2008284116B2 (cg-RX-API-DMAC7.html)
CA (1) CA2695734C (cg-RX-API-DMAC7.html)
WO (1) WO2009020844A1 (cg-RX-API-DMAC7.html)

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CN102260343A (zh) 2010-05-25 2011-11-30 健能隆医药技术(上海)有限公司 重组人g-csf二聚体在治疗神经损伤疾病中的用途
CN102380091A (zh) 2010-08-31 2012-03-21 健能隆医药技术(上海)有限公司 白介素-22在治疗病毒性肝炎中的应用
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HUE039291T2 (hu) 2013-03-15 2018-12-28 Hoffmann La Roche IL-22 polipeptidek és IL-22 FC fúziós fehérjék és alkalmazási eljárások
CN104623637A (zh) 2013-11-07 2015-05-20 健能隆医药技术(上海)有限公司 Il-22二聚体在制备静脉注射药物中的应用
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KR20220070057A (ko) 2015-03-09 2022-05-27 인테크린 테라퓨틱스, 아이엔씨. 비알코올성 지방간 질환 및/또는 지방이영양증의 치료 방법
ES2930351T3 (es) 2016-04-15 2022-12-09 Evive Biotechnology Shanghai Ltd Un dímero de IL-22 para su uso en el tratamiento de enterocolitis necrosante
SG11201909046XA (en) 2017-04-03 2019-10-30 Coherus Biosciences Inc PPARγ AGONIST FOR TREATMENT OF PROGRESSIVE SUPRANUCLEAR PALSY
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JPWO2022050230A1 (cg-RX-API-DMAC7.html) * 2020-09-03 2022-03-10

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Also Published As

Publication number Publication date
US10786551B2 (en) 2020-09-29
CN101361968A (zh) 2009-02-11
EP2185202A4 (en) 2013-11-06
JP2010535786A (ja) 2010-11-25
US20110262385A1 (en) 2011-10-27
AU2008284116B2 (en) 2014-01-09
WO2009020844A1 (en) 2009-02-12
US20140377222A1 (en) 2014-12-25
EP2185202B1 (en) 2015-05-06
EP2185202A1 (en) 2010-05-19
CA2695734A1 (en) 2009-02-12
CN101361968B (zh) 2011-08-03
US20180028614A1 (en) 2018-02-01
JP5546453B2 (ja) 2014-07-09
AU2008284116A1 (en) 2009-02-12

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