CA2684402C - Methods and compositions for treatment of disorders associated with chlamydial and similar bacterial infection - Google Patents

Methods and compositions for treatment of disorders associated with chlamydial and similar bacterial infection Download PDF

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Publication number
CA2684402C
CA2684402C CA2684402A CA2684402A CA2684402C CA 2684402 C CA2684402 C CA 2684402C CA 2684402 A CA2684402 A CA 2684402A CA 2684402 A CA2684402 A CA 2684402A CA 2684402 C CA2684402 C CA 2684402C
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CA
Canada
Prior art keywords
use according
tetracycline
infection
rifampicin
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
CA2684402A
Other languages
English (en)
French (fr)
Other versions
CA2684402A1 (en
Inventor
Thomas Julius Borody
Karl William Baumgart
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Individual
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Individual
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Publication of CA2684402A1 publication Critical patent/CA2684402A1/en
Application granted granted Critical
Publication of CA2684402C publication Critical patent/CA2684402C/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
CA2684402A 1998-06-30 1999-06-30 Methods and compositions for treatment of disorders associated with chlamydial and similar bacterial infection Expired - Lifetime CA2684402C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AUPP4376 1998-06-30
AUPP4376A AUPP437698A0 (en) 1998-06-30 1998-06-30 Methods for treatment of coronary, carotid and other vascular disease
CA2336593A CA2336593C (en) 1998-06-30 1999-06-30 Methods and compositions for treatment of disorders associated with chlamydial and similar bacterial infection

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA2336593A Division CA2336593C (en) 1998-06-30 1999-06-30 Methods and compositions for treatment of disorders associated with chlamydial and similar bacterial infection

Publications (2)

Publication Number Publication Date
CA2684402A1 CA2684402A1 (en) 2000-01-13
CA2684402C true CA2684402C (en) 2012-10-30

Family

ID=3808619

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2684402A Expired - Lifetime CA2684402C (en) 1998-06-30 1999-06-30 Methods and compositions for treatment of disorders associated with chlamydial and similar bacterial infection
CA2336593A Expired - Lifetime CA2336593C (en) 1998-06-30 1999-06-30 Methods and compositions for treatment of disorders associated with chlamydial and similar bacterial infection

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2336593A Expired - Lifetime CA2336593C (en) 1998-06-30 1999-06-30 Methods and compositions for treatment of disorders associated with chlamydial and similar bacterial infection

Country Status (10)

Country Link
US (1) US6475518B1 (enExample)
EP (2) EP1093363B1 (enExample)
JP (3) JP4651816B2 (enExample)
AT (1) ATE345115T1 (enExample)
AU (2) AUPP437698A0 (enExample)
CA (2) CA2684402C (enExample)
DE (1) DE69934010T2 (enExample)
ES (2) ES2278449T3 (enExample)
NZ (1) NZ509504A (enExample)
WO (1) WO2000001378A1 (enExample)

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US6756369B2 (en) * 1997-05-06 2004-06-29 Vanderbilt University Diagnosis and management of infection caused by Chlamydia
US6890526B2 (en) 1997-05-06 2005-05-10 Vanderbilt University Methods and reagents for the treatment of multiple sclerosis
EP1166117A2 (en) * 1999-03-19 2002-01-02 Vanderbilt University Diagnosis and treatment of multiple sclerosis
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US20020169112A1 (en) * 2001-05-08 2002-11-14 Luc Montagnier Combined treatments and methods for treatment of mycoplasma and mycoplasma-like organism infections
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AUPS017702A0 (en) * 2002-01-25 2002-02-14 Atopic Pty Ltd Methods and compositions for the treatment of asthma and related disorders
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WO2003075852A2 (en) * 2002-03-07 2003-09-18 Advancis Pharmaceuticals Corporation Antibiotic composition
US20040077533A1 (en) * 2002-05-23 2004-04-22 Sayada Chalom B. Methods and compositions for treating bacterial infections and diseases associated therewith
AU2003265241A1 (en) * 2002-05-23 2003-12-12 Activbiotics, Inc. Methods of treating bacterial infections and diseases associated therewith
US20090149453A1 (en) * 2002-05-23 2009-06-11 Activbiotics Pharma Llc Methods and compositions for treating bacterial infections and diseases associated therewith
US6916627B2 (en) * 2002-11-27 2005-07-12 St. Jude Children's Research Hospital ATM kinase compositions and methods
US7108992B2 (en) * 2002-11-27 2006-09-19 St. Jude Children's Research Hospital ATM kinase compositions and methods
WO2004054548A1 (en) * 2002-12-12 2004-07-01 Activbiotics,Inc. Method and reagents for treating or preventing atherosclerosis and diseases associated therewith
WO2004054513A2 (en) * 2002-12-12 2004-07-01 Activbiotics, Inc. Methods and compositions for treating and preventing ear infections
US20050013835A1 (en) * 2003-07-15 2005-01-20 Pfizer Inc. Stable non-dihydrate azithromycin oral suspensions
RU2254123C2 (ru) * 2003-08-11 2005-06-20 Государственное научное учреждение Институт экспериментальной ветеринарии Сибири и Дальнего Востока Сибирского отделения Россельхозакадемии (ГНУ ИЭВСиДВ СО РАСХН) Препарат для лечения гемобартонеллеза кошек и способ его применения
WO2005027961A2 (en) * 2003-09-23 2005-03-31 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Chlamydia pmpd autotransporter and its role as adhesin
NZ549661A (en) 2004-02-06 2010-07-30 Pharmatel R & D Pty Ltd As Tru Use of aminosalicylates in diarrhoea-predominant irritable bowel syndrome
JP5009152B2 (ja) * 2004-05-28 2012-08-22 サリックス ファーマシューティカルズ, インコーポレイテッド 放射線誘発性腸炎の予防、処置、および回復
JP5047797B2 (ja) 2004-09-30 2012-10-10 コヴァロン・テクノロジーズ・インコーポレーテッド 非接着性の弾性ゼラチンマトリックス
JPWO2006057429A1 (ja) * 2004-11-24 2008-06-05 ナノキャリア株式会社 ブロックコポリマーのモーフォロジーの変化方法
US7452872B2 (en) * 2005-08-24 2008-11-18 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
CN101247812A (zh) * 2005-08-24 2008-08-20 萨利克斯药品公司 巴柳氮制剂及其生产和应用
US8921344B2 (en) * 2006-11-03 2014-12-30 Salix Pharmaceuticals, Inc. Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives
FR2891744B1 (fr) * 2005-10-06 2009-10-09 France Etat Armement Application a la chimioprophylaxie du paludisme d'une association de chloroquine et de doxycycline
US8647673B2 (en) * 2007-07-24 2014-02-11 Wayne State University Nanoparticles for imaging and treating chlamydial infection
ES2645692T3 (es) 2008-11-11 2017-12-07 The Board Of Regents,The University Of Texas System Microcápsulas de rapamicina y su uso para el tratamiento del cáncer
GB2548296A (en) * 2009-10-22 2017-09-13 Borody Thomas J Novel parasite therapy
US9283211B1 (en) 2009-11-11 2016-03-15 Rapamycin Holdings, Llc Oral rapamycin preparation and use for stomatitis
US8497256B2 (en) 2010-04-26 2013-07-30 Salix Pharmaceuticals, Ltd Formulations and uses of 2-hydroxy-5-phenylazobenzoic acid derivatives for the treatment of males
NZ611868A (en) 2010-12-13 2015-11-27 Salix Pharmaceuticals Inc Gastric and colonic formulations and methods for making and using them
CN103813977A (zh) * 2011-08-16 2014-05-21 普拉克生化公司 可用于发酵液处理的通过用盐酸沉淀从羧酸镁盐中回收羧酸的方法
EP2877163B1 (en) 2012-07-27 2019-03-20 Redhill Biopharma Ltd. Formulations and methods of manufacturing formulations for use in colonic evacuation
WO2014160328A1 (en) 2013-03-13 2014-10-02 The Board Of Regents Of The University Of Texas System Mtor inhibitors for prevention of intestinal polyp growth
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US9700544B2 (en) 2013-12-31 2017-07-11 Neal K Vail Oral rapamycin nanoparticle preparations
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CN111757732A (zh) * 2018-02-01 2020-10-09 消化系统疾病中心 用于治疗感染性动脉疾病和相关病状的组合物
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Also Published As

Publication number Publication date
NZ509504A (en) 2004-04-30
EP1093363B1 (en) 2006-11-15
DE69934010D1 (de) 2006-12-28
WO2000001378A1 (en) 2000-01-13
EP1093363A4 (en) 2003-09-24
ES2278449T3 (es) 2007-08-01
JP2010174030A (ja) 2010-08-12
EP1093363A1 (en) 2001-04-25
ATE345115T1 (de) 2006-12-15
CA2336593A1 (en) 2000-01-13
JP4651816B2 (ja) 2011-03-16
JP2013147504A (ja) 2013-08-01
DE69934010T2 (de) 2007-06-21
CA2336593C (en) 2010-06-29
AU757293B2 (en) 2003-02-13
EP1754472A3 (en) 2009-08-26
US6475518B1 (en) 2002-11-05
ES2514469T3 (es) 2014-10-28
AUPP437698A0 (en) 1998-07-23
HK1037864A1 (en) 2002-02-22
JP5335726B2 (ja) 2013-11-06
EP1754472A2 (en) 2007-02-21
EP1754472B1 (en) 2014-07-23
CA2684402A1 (en) 2000-01-13
AU4591999A (en) 2000-01-24
JP2002519374A (ja) 2002-07-02

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Effective date: 20190702