CA2676435C - Substituted 1,3-dioxanes useful as ppar modulators - Google Patents

Substituted 1,3-dioxanes useful as ppar modulators Download PDF

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CA2676435C
CA2676435C CA2676435A CA2676435A CA2676435C CA 2676435 C CA2676435 C CA 2676435C CA 2676435 A CA2676435 A CA 2676435A CA 2676435 A CA2676435 A CA 2676435A CA 2676435 C CA2676435 C CA 2676435C
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alkyl
compound
solvate
linear
use according
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French (fr)
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CA2676435A1 (en
Inventor
Alexandra Santana Sorensen
Jean-Philippe Meyer
Peteris Alberts
Mainkar S. Prathama
Melya Hughes Crameri
Thierry Bonnaud
Joanne Kelleher
David Pearson
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Danstar Ferment AG
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Evolva AG
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Priority claimed from PCT/IB2007/002542 external-priority patent/WO2007138485A2/en
Application filed by Evolva AG filed Critical Evolva AG
Priority claimed from PCT/US2008/051521 external-priority patent/WO2008089461A1/en
Publication of CA2676435A1 publication Critical patent/CA2676435A1/en
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
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    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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CA2676435A 2007-01-18 2008-01-18 Substituted 1,3-dioxanes useful as ppar modulators Active CA2676435C (en)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
USPCT/IB2007/002542 2007-01-18
PCT/IB2007/002542 WO2007138485A2 (en) 2006-01-18 2007-01-18 Ppar modulators
US98980507P 2007-11-21 2007-11-21
US98980807P 2007-11-21 2007-11-21
US98980607P 2007-11-21 2007-11-21
US60/989,805 2007-11-21
US60/989,806 2007-11-21
US60/989,808 2007-11-21
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JP2014240409A (ja) 2014-12-25
JP2010516701A (ja) 2010-05-20
US20120142766A1 (en) 2012-06-07
CA2676444A1 (en) 2008-07-24
JP2010516702A (ja) 2010-05-20
CA2676435A1 (en) 2008-07-24
EP2120567A4 (en) 2011-11-09
US20150158838A1 (en) 2015-06-11
CN101641009A (zh) 2010-02-03
ES2609825T3 (es) 2017-04-24
JP5662682B2 (ja) 2015-02-04
CA2676437A1 (en) 2008-07-24
JP2010516699A (ja) 2010-05-20
MX2009007670A (es) 2011-11-18
EP2120567A1 (en) 2009-11-25
US20130197030A1 (en) 2013-08-01
MX2009007669A (es) 2011-12-08
WO2008089464A1 (en) 2008-07-24
US8536196B2 (en) 2013-09-17
JP2010516700A (ja) 2010-05-20
JP2014159487A (ja) 2014-09-04
MX2009007668A (es) 2011-12-08
CA2676444C (en) 2013-07-30

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