CA2674348A1 - Piperidine gpcr agonists - Google Patents

Piperidine gpcr agonists Download PDF

Info

Publication number
CA2674348A1
CA2674348A1 CA002674348A CA2674348A CA2674348A1 CA 2674348 A1 CA2674348 A1 CA 2674348A1 CA 002674348 A CA002674348 A CA 002674348A CA 2674348 A CA2674348 A CA 2674348A CA 2674348 A1 CA2674348 A1 CA 2674348A1
Authority
CA
Canada
Prior art keywords
pharmaceutically acceptable
acceptable salt
compound according
compounds
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002674348A
Other languages
English (en)
French (fr)
Inventor
Matthew Colin Thor Fyfe
John Keily
Simon Andrew Swain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Prosidion Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0700123A external-priority patent/GB0700123D0/en
Priority claimed from GB0719760A external-priority patent/GB0719760D0/en
Application filed by Individual filed Critical Individual
Publication of CA2674348A1 publication Critical patent/CA2674348A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Peptides Or Proteins (AREA)
CA002674348A 2007-01-04 2008-01-04 Piperidine gpcr agonists Abandoned CA2674348A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0700123.3 2007-01-04
GB0700123A GB0700123D0 (en) 2007-01-04 2007-01-04 GPCR agonists
GB0719760.1 2007-10-10
GB0719760A GB0719760D0 (en) 2007-10-10 2007-10-10 GPCR agonists
PCT/GB2008/050010 WO2008081204A1 (en) 2007-01-04 2008-01-04 Piperidine gpcr agonists

Publications (1)

Publication Number Publication Date
CA2674348A1 true CA2674348A1 (en) 2008-07-10

Family

ID=39203133

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002674348A Abandoned CA2674348A1 (en) 2007-01-04 2008-01-04 Piperidine gpcr agonists

Country Status (16)

Country Link
US (1) US20100048632A1 (enExample)
EP (2) EP2377863A1 (enExample)
JP (1) JP2010514828A (enExample)
AT (1) ATE523507T1 (enExample)
BR (1) BRPI0806498A2 (enExample)
CA (1) CA2674348A1 (enExample)
CY (1) CY1112483T1 (enExample)
DK (1) DK2114933T3 (enExample)
EA (1) EA015129B1 (enExample)
ES (1) ES2373181T3 (enExample)
HR (1) HRP20110852T1 (enExample)
PL (1) PL2114933T3 (enExample)
PT (1) PT2114933E (enExample)
RS (1) RS52065B (enExample)
SI (1) SI2114933T1 (enExample)
WO (1) WO2008081204A1 (enExample)

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Also Published As

Publication number Publication date
EP2114933B1 (en) 2011-09-07
PT2114933E (pt) 2011-12-20
JP2010514828A (ja) 2010-05-06
US20100048632A1 (en) 2010-02-25
CY1112483T1 (el) 2015-12-09
ES2373181T3 (es) 2012-02-01
PL2114933T3 (pl) 2012-02-29
HRP20110852T1 (hr) 2011-12-31
RS52065B (sr) 2012-06-30
WO2008081204A1 (en) 2008-07-10
SI2114933T1 (sl) 2012-01-31
EA200900877A1 (ru) 2010-02-26
DK2114933T3 (da) 2012-01-02
HK1135703A1 (en) 2010-06-11
EA015129B1 (ru) 2011-06-30
BRPI0806498A2 (pt) 2014-04-22
ATE523507T1 (de) 2011-09-15
EP2114933A1 (en) 2009-11-11
EP2377863A1 (en) 2011-10-19

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20140106