CA2670563A1 - Methods for treating hypercholesterolemia - Google Patents
Methods for treating hypercholesterolemia Download PDFInfo
- Publication number
- CA2670563A1 CA2670563A1 CA002670563A CA2670563A CA2670563A1 CA 2670563 A1 CA2670563 A1 CA 2670563A1 CA 002670563 A CA002670563 A CA 002670563A CA 2670563 A CA2670563 A CA 2670563A CA 2670563 A1 CA2670563 A1 CA 2670563A1
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| US8084437B2 (en) | 2006-11-27 | 2011-12-27 | Isis Pharmaceuticals, Inc. | Methods for treating hypercholesterolemia |
| US8093222B2 (en) | 2006-11-27 | 2012-01-10 | Isis Pharmaceuticals, Inc. | Methods for treating hypercholesterolemia |
| JOP20080381B1 (ar) | 2007-08-23 | 2023-03-28 | Amgen Inc | بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9) |
| AU2009213147A1 (en) | 2008-02-11 | 2009-08-20 | Rxi Pharmaceuticals Corp. | Modified RNAi polynucleotides and uses thereof |
| WO2009148605A2 (en) * | 2008-06-04 | 2009-12-10 | Isis Pharmaceuticals, Inc. | Methods for treating hypercholesterolemia |
| DK2379084T3 (en) * | 2008-10-15 | 2018-01-22 | Ionis Pharmaceuticals Inc | MODULATION OF FACTOR 11 EXPRESSION |
| AU2009323766B2 (en) | 2008-12-02 | 2016-10-06 | Wave Life Sciences Ltd. | Method for the synthesis of phosphorus atom modified nucleic acids |
| JO3672B1 (ar) | 2008-12-15 | 2020-08-27 | Regeneron Pharma | أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9). |
| US9493774B2 (en) * | 2009-01-05 | 2016-11-15 | Rxi Pharmaceuticals Corporation | Inhibition of PCSK9 through RNAi |
| CA2754043A1 (en) * | 2009-03-12 | 2010-09-16 | Alnylam Pharmaceuticals, Inc. | Lipid formulated compositions and methods for inhibiting expression of eg5 and vegf genes |
| BRPI1015236A2 (pt) * | 2009-04-15 | 2019-09-24 | Isis Pharmaceuticals Inc | métodos para modular uma resposta inflamatória, apra melhorar uma doença, distúrbio ou condição inflamatórios em um animal, para tratar um animal em risco para uma doença, distúrbio ou condição inflamatórios, para inibir a expressão de fator xi em um animal, para reduzir o risco de doença, distúrbio ou condição inflamatórios, em um animal, para tratar um animal em risco para uma doença inflamatória, e para tratar um animal tendo uma doença inflamatória, e, uso de um composto marcado para fator xi |
| NZ597504A (en) | 2009-06-15 | 2013-10-25 | Alnylam Pharmaceuticals Inc | Lipid formulated dsrna targeting the pcsk9 gene |
| US9051567B2 (en) | 2009-06-15 | 2015-06-09 | Tekmira Pharmaceuticals Corporation | Methods for increasing efficacy of lipid formulated siRNA |
| SG177564A1 (en) | 2009-07-06 | 2012-02-28 | Ontorii Inc | Novel nucleic acid prodrugs and methods of use thereof |
| EP2456870A1 (en) * | 2009-07-21 | 2012-05-30 | Santaris Pharma A/S | Antisense oligomers targeting pcsk9 |
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| US9605019B2 (en) | 2011-07-19 | 2017-03-28 | Wave Life Sciences Ltd. | Methods for the synthesis of functionalized nucleic acids |
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| SG10201912895PA (en) | 2012-07-13 | 2020-02-27 | Wave Life Sciences Ltd | Chiral control |
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-
2007
- 2007-11-27 US US12/516,457 patent/US8084437B2/en active Active
- 2007-11-27 MX MX2009005527A patent/MX2009005527A/es not_active Application Discontinuation
- 2007-11-27 EP EP11192458A patent/EP2455471A3/en not_active Withdrawn
- 2007-11-27 CA CA002670563A patent/CA2670563A1/en not_active Abandoned
- 2007-11-27 EA EA200900741A patent/EA200900741A1/ru unknown
- 2007-11-27 EP EP07862213A patent/EP2102340A2/en not_active Withdrawn
- 2007-11-27 AU AU2007325767A patent/AU2007325767A1/en not_active Abandoned
- 2007-11-27 WO PCT/US2007/024369 patent/WO2008066776A2/en not_active Ceased
- 2007-11-27 TW TW096145015A patent/TW200838551A/zh unknown
- 2007-11-27 EP EP11192464A patent/EP2453016A1/en not_active Withdrawn
- 2007-11-27 KR KR1020097013295A patent/KR20090103894A/ko not_active Withdrawn
- 2007-11-27 JP JP2009539274A patent/JP2010510807A/ja active Pending
-
2009
- 2009-05-20 IL IL198851A patent/IL198851A0/en unknown
- 2009-06-03 NO NO20092150A patent/NO20092150L/no not_active Application Discontinuation
- 2009-06-26 CO CO09066682A patent/CO6241169A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20092150L (no) | 2009-07-31 |
| EP2455471A2 (en) | 2012-05-23 |
| EA200900741A1 (ru) | 2010-04-30 |
| CO6241169A2 (es) | 2011-01-20 |
| TW200838551A (en) | 2008-10-01 |
| AU2007325767A1 (en) | 2008-06-05 |
| AU2007325767A2 (en) | 2009-07-09 |
| WO2008066776A3 (en) | 2008-09-25 |
| US20100144834A1 (en) | 2010-06-10 |
| WO2008066776A2 (en) | 2008-06-05 |
| EP2453016A1 (en) | 2012-05-16 |
| US8084437B2 (en) | 2011-12-27 |
| KR20090103894A (ko) | 2009-10-01 |
| EP2455471A3 (en) | 2012-09-12 |
| MX2009005527A (es) | 2009-06-08 |
| EP2102340A2 (en) | 2009-09-23 |
| JP2010510807A (ja) | 2010-04-08 |
| IL198851A0 (en) | 2011-08-01 |
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