CA2667372C - 1,5-diphenyl-3-benzylamino-1,5-dihydropyrrolidin-2-one as cb1 receptor modulators - Google Patents
1,5-diphenyl-3-benzylamino-1,5-dihydropyrrolidin-2-one as cb1 receptor modulators Download PDFInfo
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- CA2667372C CA2667372C CA2667372A CA2667372A CA2667372C CA 2667372 C CA2667372 C CA 2667372C CA 2667372 A CA2667372 A CA 2667372A CA 2667372 A CA2667372 A CA 2667372A CA 2667372 C CA2667372 C CA 2667372C
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- LXNFVVDCCWUUKC-UHFFFAOYSA-N methyl 4-chlorobenzoate Chemical compound COC(=O)C1=CC=C(Cl)C=C1 LXNFVVDCCWUUKC-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
Landscapes
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| US86254006P | 2006-10-23 | 2006-10-23 | |
| US60/862,540 | 2006-10-23 | ||
| PCT/US2007/082042 WO2008070306A2 (en) | 2006-10-23 | 2007-10-22 | 1,5-diphenyl-3-benzylamin0-1,5-dihydr0pyrr0lidin-2-0ne as cb1 receptor modulators |
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| CA2667372A1 CA2667372A1 (en) | 2008-06-12 |
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| CA2667210A Expired - Fee Related CA2667210C (en) | 2006-10-23 | 2007-10-22 | 1,5-diphenyl-3-pyridinylmethylamino-1,5-dihydropyrrolidin-2-one as a cb-1 receptor modulator |
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Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20080926A1 (es) * | 2006-10-23 | 2008-07-19 | Lilly Co Eli | Compuestos cb1 |
| EA201071222A1 (ru) * | 2008-04-22 | 2011-12-30 | Эли Лилли Энд Компани | Соединения 1,5-дифенилпирролидин-2-она в качестве лигандов cb-1 |
| PL2280961T3 (pl) | 2008-04-22 | 2012-12-31 | Lilly Co Eli | Związki 1,5-difenylo-pirolidyn-2-onu jako ligandy CB-1 |
| US20110280813A1 (en) * | 2008-11-13 | 2011-11-17 | Alice Prince | Neuraminidase inhibitors and uses thereof |
| DE112011102349T5 (de) * | 2010-07-15 | 2013-04-18 | Oleg Iliich Epshtein | Pharmazeutische Zusammensetzung und Behandlungsverfahren |
| EP3610890A1 (en) | 2012-11-14 | 2020-02-19 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
| WO2022132803A1 (en) * | 2020-12-14 | 2022-06-23 | The Board Of Trustees Of The Leland Stanford Junior University | Cb2 receptor agonists |
| WO2023205180A1 (en) | 2022-04-19 | 2023-10-26 | Nurix Therapeutics, Inc. | Biomarkers for cbl, and compositions and methods for their use |
| US20230414598A1 (en) | 2022-06-22 | 2023-12-28 | Nurix Therapeutics, Inc. | Combination therapies with cbl-b inhibitor compounds and antiemetic agents |
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| TW200533657A (en) | 2004-02-17 | 2005-10-16 | Esteve Labor Dr | Substituted pyrazoline compounds, their preparation and use as medicaments |
| KR20060131908A (ko) * | 2004-02-19 | 2006-12-20 | 솔베이 파마슈티칼스 비. 브이 | Ｃｂ1-길항 활성을 갖는 이미다졸린 유도체 |
| US20060035245A1 (en) * | 2004-04-20 | 2006-02-16 | Ason Brandon L | Modulators of enzymatic nucleic acid elements mobilization |
| WO2007020502A2 (en) * | 2005-08-16 | 2007-02-22 | Pharmacia & Upjohn Company Llc | Cannabinoid receptor ligands and uses thereof |
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- 2007-10-22 AT AT07871197T patent/ATE492543T1/de active
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- 2007-10-22 US US12/441,570 patent/US8168659B2/en not_active Expired - Fee Related
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- 2007-10-22 DK DK07871196.7T patent/DK2099784T3/da active
- 2007-10-22 WO PCT/US2007/082042 patent/WO2008070306A2/en not_active Ceased
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- 2007-10-22 SI SI200730538T patent/SI2094684T1/sl unknown
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- 2007-10-22 DK DK07871197.5T patent/DK2094684T3/da active
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