CA2666953A1 - Spontaneous forming ellipsoidal phospholipid unilamellar vesicles - Google Patents

Spontaneous forming ellipsoidal phospholipid unilamellar vesicles Download PDF

Info

Publication number
CA2666953A1
CA2666953A1 CA002666953A CA2666953A CA2666953A1 CA 2666953 A1 CA2666953 A1 CA 2666953A1 CA 002666953 A CA002666953 A CA 002666953A CA 2666953 A CA2666953 A CA 2666953A CA 2666953 A1 CA2666953 A1 CA 2666953A1
Authority
CA
Canada
Prior art keywords
dops
chain
liposomes
lipid
dppc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002666953A
Other languages
English (en)
French (fr)
Inventor
Xiaoyang Qi
John KATSARAS
Mu-Ping NIEH
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cincinnati Children's Hospital Medical Center
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2666953A1 publication Critical patent/CA2666953A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1275—Lipoproteins or protein-free species thereof, e.g. chylomicrons; Artificial high-density lipoproteins [HDL], low-density lipoproteins [LDL] or very-low-density lipoproteins [VLDL]; Precursors thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002666953A 2006-10-20 2007-10-19 Spontaneous forming ellipsoidal phospholipid unilamellar vesicles Abandoned CA2666953A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US86231206P 2006-10-20 2006-10-20
US60/862,312 2006-10-20
PCT/US2007/081880 WO2008051818A2 (en) 2006-10-20 2007-10-19 Spontaneously forming ellipsoidal phospholipid unilamellar vesicles

Publications (1)

Publication Number Publication Date
CA2666953A1 true CA2666953A1 (en) 2008-05-02

Family

ID=39325270

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002666953A Abandoned CA2666953A1 (en) 2006-10-20 2007-10-19 Spontaneous forming ellipsoidal phospholipid unilamellar vesicles

Country Status (7)

Country Link
US (1) US20100311844A1 (enExample)
EP (1) EP2081552A2 (enExample)
JP (1) JP5253402B2 (enExample)
CN (1) CN101541307A (enExample)
BR (1) BRPI0717475A2 (enExample)
CA (1) CA2666953A1 (enExample)
WO (1) WO2008051818A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7834147B2 (en) 2003-04-28 2010-11-16 Childrens Hospital Medical Center Saposin C-DOPS: a novel anti-tumor agent
CN101583346B (zh) * 2006-04-28 2015-08-19 儿童医院医疗中心 用于穿膜药物递送系统的皂化蛋白c和相关蛋白及肽的促融合性质
AU2008363813A1 (en) * 2008-11-07 2010-05-14 Children's Hospital Medical Center Fusogenic properties of saposin C and related proteins and peptides for application to transmembrane drug delivery systems
CN102614125B (zh) * 2011-02-01 2018-11-02 常州长吉生物技术开发有限公司 SapC-磷脂纳米囊泡冻干制剂、其制备方法及用途
ES2608857T3 (es) 2012-12-18 2017-04-17 Salipro Biotech Ag Partículas Salipro
LT3043814T (lt) 2013-09-13 2021-02-25 Salipro Biotech AB Antigenas ir jo gamybos būdas
MX2020009829A (es) 2018-03-23 2021-01-08 Bexion Pharmaceuticals Inc Composiciones farmaceuticas de saposina c y metodos para tratar el cancer.
EP4125816A4 (en) * 2020-04-01 2024-01-10 University of Cincinnati MATERIALS AND METHODS FOR CANCER THERAPY TARGETING AN IMMUNOSUPPRESSIVE TUMOR MICROENVIRONMENT
US11833254B2 (en) * 2020-05-27 2023-12-05 University Of Connecticut Discoidal nano universal platform for efficient delivery of PNAs

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4921706A (en) * 1984-11-20 1990-05-01 Massachusetts Institute Of Technology Unilamellar lipid vesicles and method for their formation
US6433040B1 (en) * 1997-09-29 2002-08-13 Inhale Therapeutic Systems, Inc. Stabilized bioactive preparations and methods of use
WO2000012553A1 (en) * 1998-08-28 2000-03-09 Myelos Corporation Cyclic prosaposin-derived peptides and uses thereof
US6872406B2 (en) * 2000-02-11 2005-03-29 Children's Hospital Research Foundation Fusogenic properties of saposin C and related proteins and polypeptides for application to transmembrane drug delivery systems
US7834147B2 (en) * 2003-04-28 2010-11-16 Childrens Hospital Medical Center Saposin C-DOPS: a novel anti-tumor agent
CN101583346B (zh) * 2006-04-28 2015-08-19 儿童医院医疗中心 用于穿膜药物递送系统的皂化蛋白c和相关蛋白及肽的促融合性质
AU2008363813A1 (en) * 2008-11-07 2010-05-14 Children's Hospital Medical Center Fusogenic properties of saposin C and related proteins and peptides for application to transmembrane drug delivery systems

Also Published As

Publication number Publication date
BRPI0717475A2 (pt) 2014-03-11
CN101541307A (zh) 2009-09-23
EP2081552A2 (en) 2009-07-29
JP5253402B2 (ja) 2013-07-31
JP2010507580A (ja) 2010-03-11
US20100311844A1 (en) 2010-12-09
WO2008051818A3 (en) 2008-12-24
WO2008051818A2 (en) 2008-05-02
WO2008051818A8 (en) 2009-08-06

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20141229