CA2651732C - Intracellular kinase inhibitors - Google Patents

Intracellular kinase inhibitors Download PDF

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Publication number
CA2651732C
CA2651732C CA2651732A CA2651732A CA2651732C CA 2651732 C CA2651732 C CA 2651732C CA 2651732 A CA2651732 A CA 2651732A CA 2651732 A CA2651732 A CA 2651732A CA 2651732 C CA2651732 C CA 2651732C
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Prior art keywords
lymphoma
leukemia
compounds
cell
itk
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CA2651732A
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French (fr)
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CA2651732A1 (en
Inventor
Gary A. Flynn
Sandra Aeyoung Lee
Mary Faris
David William Brandt
Subrata Chakravarty
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Pharmacyclics LLC
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Pharmacyclics LLC
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Priority to CA2858520A priority Critical patent/CA2858520A1/en
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
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US8604031B2 (en) 2013-12-10
US20070293499A1 (en) 2007-12-20
WO2007136790A3 (en) 2008-11-27
CA2651732A1 (en) 2007-11-29
US20110281850A1 (en) 2011-11-17
AU2007254179A1 (en) 2007-11-29
EP2865381A1 (en) 2015-04-29
US20140080833A1 (en) 2014-03-20
CA2858520A1 (en) 2007-11-29
AU2007254179B2 (en) 2013-03-21
JP2016040248A (ja) 2016-03-24
WO2007136790A2 (en) 2007-11-29
JP2014098004A (ja) 2014-05-29
JP5682051B2 (ja) 2015-03-11
EP2027087A2 (en) 2009-02-25
MX2008014450A (es) 2009-03-09

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