AU2007254179B2 - Intracellular kinase inhibitors - Google Patents
Intracellular kinase inhibitors Download PDFInfo
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- AU2007254179B2 AU2007254179B2 AU2007254179A AU2007254179A AU2007254179B2 AU 2007254179 B2 AU2007254179 B2 AU 2007254179B2 AU 2007254179 A AU2007254179 A AU 2007254179A AU 2007254179 A AU2007254179 A AU 2007254179A AU 2007254179 B2 AU2007254179 B2 AU 2007254179B2
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- lymphoma
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- leukemia
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
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- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
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- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
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- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
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- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
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- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
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- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- C07D333/56—Radicals substituted by oxygen atoms
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- 2007-05-18 CA CA2651732A patent/CA2651732C/en active Active
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- 2007-05-18 US US11/750,866 patent/US8604031B2/en not_active Expired - Fee Related
- 2007-05-18 WO PCT/US2007/011974 patent/WO2007136790A2/en not_active Ceased
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2011
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2013
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2014
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2015
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Also Published As
| Publication number | Publication date |
|---|---|
| WO2007136790A3 (en) | 2008-11-27 |
| JP2009537552A (ja) | 2009-10-29 |
| US20110281850A1 (en) | 2011-11-17 |
| US20140080833A1 (en) | 2014-03-20 |
| JP2016040248A (ja) | 2016-03-24 |
| EP2027087A2 (en) | 2009-02-25 |
| AU2007254179A1 (en) | 2007-11-29 |
| CA2651732A1 (en) | 2007-11-29 |
| JP5682051B2 (ja) | 2015-03-11 |
| JP2014098004A (ja) | 2014-05-29 |
| CA2651732C (en) | 2014-10-14 |
| CA2858520A1 (en) | 2007-11-29 |
| US8604031B2 (en) | 2013-12-10 |
| US20070293499A1 (en) | 2007-12-20 |
| EP2865381A1 (en) | 2015-04-29 |
| WO2007136790A2 (en) | 2007-11-29 |
| US20150290200A1 (en) | 2015-10-15 |
| MX2008014450A (es) | 2009-03-09 |
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Owner name: PHARMACYCLICS, INC. Free format text: FORMER OWNER WAS: MANNKIND CORPORATION |
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| MK14 | Patent ceased section 143(a) (annual fees not paid) or expired |