CA2647119C - Fluorescence based detection of substances - Google Patents

Fluorescence based detection of substances Download PDF

Info

Publication number
CA2647119C
CA2647119C CA2647119A CA2647119A CA2647119C CA 2647119 C CA2647119 C CA 2647119C CA 2647119 A CA2647119 A CA 2647119A CA 2647119 A CA2647119 A CA 2647119A CA 2647119 C CA2647119 C CA 2647119C
Authority
CA
Canada
Prior art keywords
antibodies
antibody
metal
protein
substrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2647119A
Other languages
English (en)
French (fr)
Other versions
CA2647119A1 (en
Inventor
David Russell
Richard Leggett
Emma Lee-Smith
Sue Jickells
Barbara Daniel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intelligent Fingerprinting Ltd
Original Assignee
Intelligent Fingerprinting Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intelligent Fingerprinting Ltd filed Critical Intelligent Fingerprinting Ltd
Publication of CA2647119A1 publication Critical patent/CA2647119A1/en
Application granted granted Critical
Publication of CA2647119C publication Critical patent/CA2647119C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites

Landscapes

  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nanotechnology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Composite Materials (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
CA2647119A 2006-03-24 2007-03-23 Fluorescence based detection of substances Active CA2647119C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0605965.3 2006-03-24
GBGB0605965.3A GB0605965D0 (en) 2006-03-24 2006-03-24 Fluorescence based detection of substances
PCT/GB2007/001059 WO2007110605A2 (en) 2006-03-24 2007-03-23 Fluorescence based detection of substances

Publications (2)

Publication Number Publication Date
CA2647119A1 CA2647119A1 (en) 2007-10-04
CA2647119C true CA2647119C (en) 2014-05-27

Family

ID=36384143

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2647119A Active CA2647119C (en) 2006-03-24 2007-03-23 Fluorescence based detection of substances

Country Status (9)

Country Link
US (1) US8455264B2 (https=)
EP (1) EP2005179B1 (https=)
JP (1) JP5608853B2 (https=)
AT (1) ATE516501T1 (https=)
AU (1) AU2007231207B2 (https=)
CA (1) CA2647119C (https=)
ES (1) ES2366663T3 (https=)
GB (1) GB0605965D0 (https=)
WO (1) WO2007110605A2 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120164073A1 (en) * 2007-11-30 2012-06-28 Old Dominion University Stable nanoparticles, nanoparticle-based imaging systems, nanoparticle-based assays, and in vivo assays for screening biocompatibility and toxicity of nanoparticles
AU2012325697B2 (en) * 2011-10-21 2015-11-26 Decimadx, Llc Point-of care immunoassay for quantitative small analyte detection
US10112987B2 (en) * 2012-01-09 2018-10-30 Icb International, Inc. Blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an amyloid-beta peptide
US10112988B2 (en) 2012-01-09 2018-10-30 Icb International, Inc. Methods of assessing amyloid-beta peptides in the central nervous system by blood-brain barrier permeable peptide compositions comprising a vab domain of a camelid single domain heavy chain antibody against an anti-amyloid-beta peptide
CN103226099A (zh) * 2013-03-25 2013-07-31 常州大学 磷酸铁锂中三价铁含量的测定
CN103536297B (zh) * 2013-10-18 2015-06-17 浙江大学 基于免疫胶体金的潜在指纹成像的方法
GB2520063B (en) 2013-11-08 2018-01-31 Intelligent Fingerprinting Ltd Skin-print fluorescence analysis method and apparatus
GB201403115D0 (en) * 2014-02-21 2014-04-09 Qbd Qs Ip Ltd Red blood cell detection
CN104090050B (zh) * 2014-07-08 2015-10-28 复旦大学 一种基于磁性材料的膜蛋白共价固定方法
CN104678050A (zh) * 2015-02-05 2015-06-03 北大先行科技产业有限公司 碘量法测定磷酸铁锂中三价铁含量的方法
GB2535998A (en) * 2015-02-27 2016-09-07 Intelligent Fingerprinting Ltd A device for receiving and analysing a sample
JP6769360B2 (ja) * 2017-03-17 2020-10-14 コニカミノルタ株式会社 蛍光体集積粒子複合体を用いた多段階蛍光染色方法および蛍光体集積粒子複合体
KR102582297B1 (ko) 2017-05-19 2023-09-25 필립모리스 프로덕츠 에스.에이. 대상체의 흡연 상태를 구별하기 위한 진단 테스트
US10994993B2 (en) * 2019-08-22 2021-05-04 National Central University Method of forming enhanced super-resolution image
CN113252593B (zh) * 2021-06-29 2021-09-17 广州智汇生物科技有限公司 一种宠物食品中非法添加中枢神经兴奋类药物烟酸二乙胺的检测方法
US20230104609A1 (en) * 2021-10-04 2023-04-06 Tintoria Piana, Inc Diagnostic system and methods of using and manufacturing the same
CN119322175A (zh) * 2024-10-18 2025-01-17 武汉塞力斯生物技术有限公司 一种血管炎抗体联检试剂盒

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60222033A (ja) * 1984-04-18 1985-11-06 田岡化学工業株式会社 指紋の検出方法
DE3872691T2 (de) 1988-01-14 1992-12-03 Basf Ag Verfahren zur beherrschung der freisetzung von monomeren.
US5202267A (en) * 1988-04-04 1993-04-13 Hygeia Sciences, Inc. Sol capture immunoassay kit and procedure
US5244815A (en) * 1990-01-19 1993-09-14 Lamina Ltd. Fingerprint test pad and method for fingerprinting using particle based immunoassay
DE69127383T2 (de) * 1990-01-19 1998-03-05 Mina Ltd Gerät und Verfahren zur Untersuchung von Blut und zur Fingerabdruck-Identifikation
JP3731891B2 (ja) * 1992-10-21 2006-01-05 ミルテンイ,ステファン 分泌生成物による細胞の直接選択
US5494831A (en) * 1993-08-30 1996-02-27 Hughes Aircraft Company Electrochemical immunosensor system and methods
CA2223439A1 (en) * 1995-06-06 1996-12-12 Jonathan Braun Anti-neutrophil cytoplasmic antibody material associated with ulcerative colitis and related methods and kits
US6582921B2 (en) * 1996-07-29 2003-06-24 Nanosphere, Inc. Nanoparticles having oligonucleotides attached thereto and uses thereof
US6165798A (en) * 1996-10-10 2000-12-26 University Of British Columbia Optical quantification of analytes in membranes
DE10027776A1 (de) 2000-06-07 2002-02-14 Roche Diagnostics Gmbh Neuartige core-shell Partikel
US20020192841A1 (en) * 2001-04-27 2002-12-19 Masayoshi Kojima Measurement chip for biosensor
WO2002096262A2 (en) * 2001-05-25 2002-12-05 Northwestern University Non-alloying core shell nanoparticles
WO2003027678A1 (en) * 2001-09-26 2003-04-03 Psychiatric Genomics, Inc. Fluorescence proximity assay
JP2004149507A (ja) * 2002-09-05 2004-05-27 Hisamitsu Pharmaceut Co Inc 免疫抑制剤
CN1245625C (zh) * 2003-04-30 2006-03-15 陕西西大北美基因股份有限公司 一种核/壳型超顺磁性复合微粒及其制备方法与应用
ES2385829T3 (es) * 2003-08-20 2012-08-01 Ucb Pharma, S.A. Métodos para obtener anticuerpos
GB0400235D0 (en) 2004-01-07 2004-02-11 Univ Sunderland Nanoparticles as agents for imaging finger prints
US7625712B2 (en) * 2004-05-21 2009-12-01 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential
ES2686677T3 (es) 2007-12-21 2018-10-19 Biomerieux Sa Detección de Staphylococcus aureus resistente a meticilina

Also Published As

Publication number Publication date
US20090230322A1 (en) 2009-09-17
AU2007231207A1 (en) 2007-10-04
US8455264B2 (en) 2013-06-04
WO2007110605A3 (en) 2008-01-24
WO2007110605A2 (en) 2007-10-04
ES2366663T3 (es) 2011-10-24
ATE516501T1 (de) 2011-07-15
EP2005179B1 (en) 2011-07-13
AU2007231207B2 (en) 2012-09-06
CA2647119A1 (en) 2007-10-04
JP2009531694A (ja) 2009-09-03
EP2005179A2 (en) 2008-12-24
GB0605965D0 (en) 2006-05-03
JP5608853B2 (ja) 2014-10-15

Similar Documents

Publication Publication Date Title
CA2647119C (en) Fluorescence based detection of substances
Han et al. Label-free detection in biological applications of surface-enhanced Raman scattering
Jans et al. Dynamic light scattering as a powerful tool for gold nanoparticle bioconjugation and biomolecular binding studies
Sun et al. Microminiaturized immunoassays using quantum dots as fluorescent label by laser confocal scanning fluorescence detection
KR101195957B1 (ko) 표면증강 라만 산란 복합 프로브 및 이를 이용하여 표적 물질을 검출하는 방법
Kim et al. Dual-mode fluorophore-doped nickel nitrilotriacetic acid-modified silica nanoparticles combine histidine-tagged protein purification with site-specific fluorophore labeling
JP2007506084A (ja) ナノ粒子コンジュゲート及びその製造方法
Oliveira et al. Microfluidic SERS devices: brightening the future of bioanalysis
CN104316698A (zh) 固定有抗原的免疫荧光载片的制备方法和由该方法制备的免疫荧光载片
CN101978254A (zh) 使用金属纳米粒子探针和动态光散射的分析物检测
JP7284470B2 (ja) 生体分子の検出のための温度応答性蛍光粒子
Kang et al. Specific adsorption of histidine-tagged proteins on silica surfaces modified with Ni2+/NTA-derivatized poly (ethylene glycol)
Braz et al. Gold-binding peptide as a selective layer for electrochemical detection of SARS-CoV-2 antibodies
EP2957912A1 (en) A method of labelling a target molecule forming part of a corona of molecules on a surface of a nanosized object
Chen et al. Sensitive detection of enrofloxacin using an electrochemiluminescence immunosensor based on gold-functionalized C 60 and Au@ BSA nanoflowers
McColman et al. Serum proteins on nanoparticles: early stages of the “protein corona”
Heinecke et al. Preparation of gold nanocluster bioconjugates for electron microscopy
CN105051539A (zh) 用于使用发光检测生物分子的方法和试剂
Cháfer-Pericás et al. Functionalized inorganic nanoparticles used as labels in solid-phase immunoassays
Chaloupková et al. Surface-enhanced Raman spectroscopy-assisted lateral flow test for adenine and IgG analysis
Powell et al. Giant platinum clusters: 2-nm covalent metal cluster labels
KR101115388B1 (ko) 히스티딘 특이적 바이오센서 및 이의 제조방법
Nakashima et al. Pattern formation and molecular transport of histidine-tagged GFPs using supported lipid bilayers
RU2733884C1 (ru) Нано- и микрочастицы для изоляции специфических субпопуляций экзосом и их анализа
Hainfeld et al. Nanoparticle molecular labels

Legal Events

Date Code Title Description
EEER Examination request
H11 Ip right ceased following rejected request for revival

Free format text: ST27 STATUS EVENT CODE: T-6-6-H10-H11-H101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: TIME LIMIT FOR REVERSAL EXPIRED

Effective date: 20250925

H13 Ip right lapsed

Free format text: ST27 STATUS EVENT CODE: N-4-6-H10-H13-H100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE AND LATE FEE NOT PAID BY DEADLINE OF NOTICE

Effective date: 20251106