CA2630884A1 - Inhibitors of c-met and uses thereof - Google Patents
Inhibitors of c-met and uses thereof Download PDFInfo
- Publication number
- CA2630884A1 CA2630884A1 CA002630884A CA2630884A CA2630884A1 CA 2630884 A1 CA2630884 A1 CA 2630884A1 CA 002630884 A CA002630884 A CA 002630884A CA 2630884 A CA2630884 A CA 2630884A CA 2630884 A1 CA2630884 A1 CA 2630884A1
- Authority
- CA
- Canada
- Prior art keywords
- aliphatic
- optionally substituted
- dmso
- compound according
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
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- 125000001424 substituent group Chemical group 0.000 claims description 37
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- 150000003839 salts Chemical class 0.000 claims description 21
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/433—Thidiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US74074105P | 2005-11-30 | 2005-11-30 | |
| US74085905P | 2005-11-30 | 2005-11-30 | |
| US74073705P | 2005-11-30 | 2005-11-30 | |
| US60/740,737 | 2005-11-30 | ||
| US60/740,741 | 2005-11-30 | ||
| US60/740,859 | 2005-11-30 | ||
| PCT/US2006/045847 WO2007064797A2 (en) | 2005-11-30 | 2006-11-30 | Inhibitors of c-met and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2630884A1 true CA2630884A1 (en) | 2007-06-07 |
Family
ID=37998312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002630884A Abandoned CA2630884A1 (en) | 2005-11-30 | 2006-11-30 | Inhibitors of c-met and uses thereof |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US7728017B2 (enExample) |
| EP (1) | EP1963329B1 (enExample) |
| JP (1) | JP5144532B2 (enExample) |
| KR (1) | KR20080080584A (enExample) |
| AU (1) | AU2006320580B2 (enExample) |
| BR (1) | BRPI0619252A2 (enExample) |
| CA (1) | CA2630884A1 (enExample) |
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| NO (1) | NO20082880L (enExample) |
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| DE10038019A1 (de) * | 2000-08-04 | 2002-02-14 | Bayer Ag | Substituierte Triazolopyrid(az)ine |
| US7122548B2 (en) * | 2003-07-02 | 2006-10-17 | Sugen, Inc. | Triazolotriazine compounds and uses thereof |
| AU2006331912B2 (en) * | 2005-12-21 | 2012-08-30 | Janssen Pharmaceutica, N.V. | Triazolopyridazines as tyrosine kinase modulators |
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- 2006-11-30 JP JP2008543461A patent/JP5144532B2/ja not_active Expired - Fee Related
- 2006-11-30 KR KR1020087015565A patent/KR20080080584A/ko not_active Ceased
- 2006-11-30 BR BRPI0619252-1A patent/BRPI0619252A2/pt not_active Application Discontinuation
- 2006-11-30 WO PCT/US2006/045847 patent/WO2007064797A2/en not_active Ceased
- 2006-11-30 US US11/606,524 patent/US7728017B2/en not_active Expired - Fee Related
- 2006-11-30 AU AU2006320580A patent/AU2006320580B2/en not_active Ceased
- 2006-11-30 MX MX2008007049A patent/MX2008007049A/es not_active Application Discontinuation
- 2006-11-30 CA CA002630884A patent/CA2630884A1/en not_active Abandoned
- 2006-11-30 EP EP06838683A patent/EP1963329B1/en active Active
- 2006-11-30 NZ NZ568666A patent/NZ568666A/en not_active IP Right Cessation
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Also Published As
| Publication number | Publication date |
|---|---|
| KR20080080584A (ko) | 2008-09-04 |
| WO2007064797A2 (en) | 2007-06-07 |
| JP2009518296A (ja) | 2009-05-07 |
| US20100190774A1 (en) | 2010-07-29 |
| NZ568666A (en) | 2011-09-30 |
| IL191623A0 (en) | 2008-12-29 |
| EP1963329A2 (en) | 2008-09-03 |
| MX2008007049A (es) | 2008-10-23 |
| BRPI0619252A2 (pt) | 2011-09-20 |
| AU2006320580B2 (en) | 2011-06-23 |
| NO20082880L (no) | 2008-09-01 |
| EP1963329B1 (en) | 2013-01-23 |
| WO2007064797A3 (en) | 2007-12-13 |
| US20070191369A1 (en) | 2007-08-16 |
| JP5144532B2 (ja) | 2013-02-13 |
| AU2006320580A1 (en) | 2007-06-07 |
| US7728017B2 (en) | 2010-06-01 |
| US7998987B2 (en) | 2011-08-16 |
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