CA2596227A1 - Improved modalities for the treatment of degenerative diseases of the retina - Google Patents

Improved modalities for the treatment of degenerative diseases of the retina Download PDF

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Publication number
CA2596227A1
CA2596227A1 CA002596227A CA2596227A CA2596227A1 CA 2596227 A1 CA2596227 A1 CA 2596227A1 CA 002596227 A CA002596227 A CA 002596227A CA 2596227 A CA2596227 A CA 2596227A CA 2596227 A1 CA2596227 A1 CA 2596227A1
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cells
rpe
hes
pigmented
cell
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CA002596227A
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English (en)
French (fr)
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Irina Klimanskaya
Robert Lanza
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Harvard University
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
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    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A—HUMAN NECESSITIES
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    • A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
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    • A61P27/06—Antiglaucoma agents or miotics
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/062—Sensory transducers, e.g. photoreceptors; Sensory neurons, e.g. for hearing, taste, smell, pH, touch, temperature, pain
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Reproductive Health (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Psychology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA002596227A 2005-01-24 2005-07-20 Improved modalities for the treatment of degenerative diseases of the retina Pending CA2596227A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11/041,382 2005-01-24
US11/041,382 US7794704B2 (en) 2004-01-23 2005-01-24 Methods for producing enriched populations of human retinal pigment epithelium cells for treatment of retinal degeneration
PCT/US2005/025860 WO2006080952A2 (en) 2005-01-24 2005-07-20 Improved modalities for the treatment of degenerative diseases of the retina

Publications (1)

Publication Number Publication Date
CA2596227A1 true CA2596227A1 (en) 2006-08-03

Family

ID=36740924

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002596227A Pending CA2596227A1 (en) 2005-01-24 2005-07-20 Improved modalities for the treatment of degenerative diseases of the retina

Country Status (7)

Country Link
US (12) US7794704B2 (cg-RX-API-DMAC10.html)
EP (3) EP2479262A1 (cg-RX-API-DMAC10.html)
JP (6) JP2008530984A (cg-RX-API-DMAC10.html)
AU (1) AU2005325753B2 (cg-RX-API-DMAC10.html)
CA (1) CA2596227A1 (cg-RX-API-DMAC10.html)
HK (1) HK1215960A1 (cg-RX-API-DMAC10.html)
WO (1) WO2006080952A2 (cg-RX-API-DMAC10.html)

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