CA2594730A1 - Methods and products for in vitro genotyping - Google Patents

Methods and products for in vitro genotyping Download PDF

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Publication number
CA2594730A1
CA2594730A1 CA002594730A CA2594730A CA2594730A1 CA 2594730 A1 CA2594730 A1 CA 2594730A1 CA 002594730 A CA002594730 A CA 002594730A CA 2594730 A CA2594730 A CA 2594730A CA 2594730 A1 CA2594730 A1 CA 2594730A1
Authority
CA
Canada
Prior art keywords
seq
probes
genotype
probe
genetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002594730A
Other languages
English (en)
French (fr)
Inventor
Laureano Simon Buela
Antonio Martinez Martinez
Diego Tejedor Hernandez
Elisa Jimenez Uribe
Monica Lopez Martinez
Marta Artieda Osenalde
Lorena Hernandez Garcia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Progenika Biopharma SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES200502423A external-priority patent/ES2326708B1/es
Application filed by Individual filed Critical Individual
Publication of CA2594730A1 publication Critical patent/CA2594730A1/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Dermatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CA002594730A 2005-01-13 2006-01-12 Methods and products for in vitro genotyping Abandoned CA2594730A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
ES200500089 2005-01-13
ESP200500089 2005-01-13
ESP200502423 2005-10-05
ES200502423A ES2326708B1 (es) 2005-10-05 2005-10-05 Metodos y productos para genotipado in vitro.
US75819206P 2006-01-12 2006-01-12
US60/758,192 2006-01-12
PCT/IB2006/000796 WO2006075254A2 (en) 2005-01-13 2006-01-12 Methods and products for in vitro genotyping

Publications (1)

Publication Number Publication Date
CA2594730A1 true CA2594730A1 (en) 2006-07-20

Family

ID=36677993

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002594730A Abandoned CA2594730A1 (en) 2005-01-13 2006-01-12 Methods and products for in vitro genotyping

Country Status (7)

Country Link
US (1) US7914990B2 (enExample)
EP (1) EP1836322B8 (enExample)
JP (1) JP2008526249A (enExample)
AU (1) AU2006205571B2 (enExample)
CA (1) CA2594730A1 (enExample)
MX (1) MX2007008506A (enExample)
WO (1) WO2006075254A2 (enExample)

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US8688385B2 (en) * 2003-02-20 2014-04-01 Mayo Foundation For Medical Education And Research Methods for selecting initial doses of psychotropic medications based on a CYP2D6 genotype
JP5348840B2 (ja) 2003-02-20 2013-11-20 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ 薬物を選択する方法
US8153363B2 (en) * 2005-01-13 2012-04-10 Progenika Biopharma S.A. Methods and products for in vitro genotyping
CA2911569C (en) 2005-11-29 2019-11-26 Children's Hospital Medical Center Optimization and individualization of medication selection and dosing
GB0613844D0 (en) * 2006-07-12 2006-08-23 Progenika Biopharma Sa Methods and products for in vitro genotyping
WO2008066164A1 (fr) * 2006-11-30 2008-06-05 Arkray, Inc. Ensemble d'amorces utilisé dans l'amplification du gène de l'obésité, réactif utilisé dans l'amplification du gène de l'obésité comprenant ledit ensemble d'amorce et son utilisation
WO2008066161A1 (en) * 2006-11-30 2008-06-05 Arkray, Inc. Primer set for amplification of nat2 gene, reagent for amplification of nat2 gene comprising the same, and use of the same
JPWO2008066163A1 (ja) * 2006-11-30 2010-03-11 アークレイ株式会社 Cyp2c9遺伝子増幅用プライマーセット、それを含むcyp2c9遺伝子増幅用試薬およびその用途
ITMI20070504A1 (it) 2007-03-13 2008-09-14 Fond Irccs Ospedale Maggiore Metodo per la tipizzazione genomica di sistemi eritrocitari, sonde oligonucleotidiche e kit diagnostici relativi
JP4410269B2 (ja) * 2007-03-28 2010-02-03 株式会社東芝 N−アセチルトランスフェラーゼ2(nat2)の遺伝子型を検出するための核酸プライマーセット、キット、及び該プライマーセットを用いた検出方法
US20100311052A1 (en) * 2007-06-29 2010-12-09 Biomonitor A/S Prognostic method for the determination of the suitability of biopharmaceutical treatment
WO2009048027A1 (ja) * 2007-10-09 2009-04-16 Arkray, Inc. 免疫関連遺伝子の多型の検出用プローブおよびその用途
CA2721651A1 (en) * 2008-04-18 2009-12-03 University Of Tennessee Research Foundation Single nucleotide polymorphisms (snp) and association with resistance to immune tolerance induction
WO2009130797A1 (ja) * 2008-04-22 2009-10-29 東洋鋼鈑株式会社 Abo式血液型を判定するためのプローブセット
US20110229471A1 (en) 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
US9580752B2 (en) * 2008-12-24 2017-02-28 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (MR-UC) requiring colectomy
US8835111B2 (en) 2009-03-12 2014-09-16 Brainco Biopharma S.L. Genotyping tool for improving the prognostic and clinical management of MS patients
WO2011027218A1 (en) * 2009-09-04 2011-03-10 Progenika Biopharma, S.A. High throughput detection of genomic copy number variations
US9677125B2 (en) * 2009-10-21 2017-06-13 General Electric Company Detection of plurality of targets in biological samples
US9558320B2 (en) * 2009-10-26 2017-01-31 Genomas, Inc. Physiogenomic method for predicting drug metabolism reserve for antidepressants and stimulants
WO2011155531A1 (ja) * 2010-06-08 2011-12-15 独立行政法人国立がん研究センター 薬剤性肺障害の発症のリスク予測、該リスク予測のための遺伝子の検出方法及び検出用キット
ES2641600T3 (es) 2010-06-18 2017-11-10 Progenika Biopharma, S.A. Métodos de determinación de la presencia o la ausencia de segmentos genéticos
US8766034B2 (en) 2010-09-22 2014-07-01 Cedars-Sinai Medical Center TL1A model of inflammation fibrosis and autoimmunity
EP2471949B1 (en) * 2010-12-31 2013-12-25 Progenika Biopharma, S.A. Method for the identification by molecular techniques of genetic variants that encode no D antigen (D-) and altered C antigen (C+W)
JP2012196209A (ja) * 2011-03-09 2012-10-18 Arkray Inc Cyp3a遺伝子の多型検出用プローブ、多型検出方法、薬効評価方法及び多型検出用試薬キット
EP2535424B1 (en) * 2011-06-16 2015-08-05 Gendiag.exe, S.L. SNPs associated with thromboemoblic disease
US10557170B2 (en) 2011-06-16 2020-02-11 Gendiag.Exe, S.L. Thromboembolic disease markers
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AR088867A1 (es) * 2011-11-15 2014-07-16 Acgt Intellectual Ltd Metodo y aparato para detectar variacion(es) del acido nucleico
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ES2759782T3 (es) * 2012-01-18 2020-05-12 Shanghai Blood Centre Procedimiento de detección por PCR múltiplex para tipos sanguíneos humanos poco comunes y kit
JP6028300B2 (ja) * 2012-08-31 2016-11-16 東洋鋼鈑株式会社 Abo式血液型を判定するためのプライマーセット及びプローブ
US20140274763A1 (en) * 2013-03-15 2014-09-18 Pathway Genomics Corporation Method and system to predict response to pain treatments
EP3639841B1 (en) 2013-03-27 2023-09-06 Cedars-Sinai Medical Center Treating fibrosis by inhibiting tl1a
EP3022295A4 (en) 2013-07-19 2017-03-01 Cedars-Sinai Medical Center Signature of tl1a (tnfsf15) signaling pathway
JP2015128399A (ja) * 2014-01-09 2015-07-16 東洋紡株式会社 Cyp3a5の検出方法
JP7082945B2 (ja) 2016-03-17 2022-06-09 シーダーズ―シナイ メディカル センター Rnaset2により炎症性腸疾患を診断する方法
US11699069B2 (en) * 2017-07-13 2023-07-11 Helix, Inc. Predictive assignments that relate to genetic information and leverage machine learning models
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EP3697933A4 (en) 2017-10-20 2021-12-08 The Governors of the University of Alberta SINGLE NUCLEOTIDE POLYMORPHISMS AND FEEDING EFFICIENCY IN Cattle
JP6995604B2 (ja) * 2017-12-15 2022-01-14 東洋鋼鈑株式会社 一塩基多型検出用プローブの設計方法及びプローブセット
JP7308261B2 (ja) * 2018-08-30 2023-07-13 ライフ テクノロジーズ コーポレーション ジェノタイピングpcrアッセイのための機械学習システム
JP7706698B2 (ja) * 2020-02-14 2025-07-14 東レ株式会社 バイオチップの製造方法
CN112442532B (zh) * 2020-08-27 2023-09-26 深圳市卫生健康发展研究中心 同时检测20种葡萄糖-6-磷酸脱氢酶缺乏症的引物组及试剂盒

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CA2490766A1 (en) * 2002-06-28 2004-01-08 Applera Corporation A system and method for snp genotype clustering

Also Published As

Publication number Publication date
US7914990B2 (en) 2011-03-29
WO2006075254A3 (en) 2007-03-22
JP2008526249A (ja) 2008-07-24
MX2007008506A (es) 2010-05-17
EP1836322B8 (en) 2017-01-11
AU2006205571A1 (en) 2006-07-20
EP1836322A2 (en) 2007-09-26
US20080070253A1 (en) 2008-03-20
EP1836322B1 (en) 2016-09-07
WO2006075254A2 (en) 2006-07-20
AU2006205571B2 (en) 2012-03-22

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Effective date: 20170330