CA2594730A1 - Methods and products for in vitro genotyping - Google Patents

Methods and products for in vitro genotyping Download PDF

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Publication number
CA2594730A1
CA2594730A1 CA002594730A CA2594730A CA2594730A1 CA 2594730 A1 CA2594730 A1 CA 2594730A1 CA 002594730 A CA002594730 A CA 002594730A CA 2594730 A CA2594730 A CA 2594730A CA 2594730 A1 CA2594730 A1 CA 2594730A1
Authority
CA
Canada
Prior art keywords
seq
probes
genotype
probe
genetic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002594730A
Other languages
English (en)
French (fr)
Inventor
Laureano Simon Buela
Antonio Martinez Martinez
Diego Tejedor Hernandez
Elisa Jimenez Uribe
Monica Lopez Martinez
Marta Artieda Osenalde
Lorena Hernandez Garcia
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Progenika Biopharma SA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ES200502423A external-priority patent/ES2326708B1/es
Application filed by Individual filed Critical Individual
Publication of CA2594730A1 publication Critical patent/CA2594730A1/en
Abandoned legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6881Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6834Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/16Primer sets for multiplex assays
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002594730A 2005-01-13 2006-01-12 Methods and products for in vitro genotyping Abandoned CA2594730A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
ES200500089 2005-01-13
ESP200500089 2005-01-13
ES200502423A ES2326708B1 (es) 2005-10-05 2005-10-05 Metodos y productos para genotipado in vitro.
ESP200502423 2005-10-05
US75819206P 2006-01-12 2006-01-12
PCT/IB2006/000796 WO2006075254A2 (en) 2005-01-13 2006-01-12 Methods and products for in vitro genotyping
US60/758,192 2006-01-12

Publications (1)

Publication Number Publication Date
CA2594730A1 true CA2594730A1 (en) 2006-07-20

Family

ID=36677993

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002594730A Abandoned CA2594730A1 (en) 2005-01-13 2006-01-12 Methods and products for in vitro genotyping

Country Status (7)

Country Link
US (1) US7914990B2 (enExample)
EP (1) EP1836322B8 (enExample)
JP (1) JP2008526249A (enExample)
AU (1) AU2006205571B2 (enExample)
CA (1) CA2594730A1 (enExample)
MX (1) MX2007008506A (enExample)
WO (1) WO2006075254A2 (enExample)

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US8688385B2 (en) * 2003-02-20 2014-04-01 Mayo Foundation For Medical Education And Research Methods for selecting initial doses of psychotropic medications based on a CYP2D6 genotype
WO2004074456A2 (en) 2003-02-20 2004-09-02 Mayo Foundation For Medical Education And Research Methods for selecting medications
US8153363B2 (en) 2005-01-13 2012-04-10 Progenika Biopharma S.A. Methods and products for in vitro genotyping
EP1958111A4 (en) 2005-11-29 2009-07-08 Childrens Hosp Medical Center OPTIMIZATION AND INDIVIDUALIZATION OF THE SELECTION AND DOSAGE OF MEDICAMENTS
GB0613844D0 (en) 2006-07-12 2006-08-23 Progenika Biopharma Sa Methods and products for in vitro genotyping
CN102154274A (zh) * 2006-11-30 2011-08-17 爱科来株式会社 Nat2基因扩增用引物对、含有其的nat2基因扩增用试剂及其用途
EP2055776A4 (en) 2006-11-30 2009-11-25 Arkray Inc PRIMER ASSEMBLY FOR OBESITY GENE AMPLIFICATION, REAGENT FOR OBESITY GENE AMPLIFICATION COMPRISING THE PRIMER ASSEMBLY AND USE THEREOF
WO2008066163A1 (en) * 2006-11-30 2008-06-05 Arkray, Inc. Primer set for amplification of cyp2c9 gene, reagent for amplification of cyp2c9 gene comprising the same, and use of the same
ITMI20070504A1 (it) * 2007-03-13 2008-09-14 Fond Irccs Ospedale Maggiore Metodo per la tipizzazione genomica di sistemi eritrocitari, sonde oligonucleotidiche e kit diagnostici relativi
JP4410269B2 (ja) * 2007-03-28 2010-02-03 株式会社東芝 N−アセチルトランスフェラーゼ2(nat2)の遺伝子型を検出するための核酸プライマーセット、キット、及び該プライマーセットを用いた検出方法
EP2173896A2 (en) * 2007-06-29 2010-04-14 Biomonitor A/S Prognostic method for the determination of the suitability of biopharmaceutical treatment
JP5290957B2 (ja) * 2007-10-09 2013-09-18 アークレイ株式会社 免疫関連遺伝子の多型の検出用プローブおよびその用途
JP2011520425A (ja) * 2008-04-18 2011-07-21 ザ ユニバーシティー オブ テネシー リサーチ ファウンデーション 一塩基多型(snp)および免疫寛容の誘導に対する耐性との関連
WO2009130797A1 (ja) * 2008-04-22 2009-10-29 東洋鋼鈑株式会社 Abo式血液型を判定するためのプローブセット
WO2010062960A2 (en) 2008-11-26 2010-06-03 Cedars-Sinai Medical Center METHODS OF DETERMINING RESPONSIVENESS TO ANTI-TNFα THERAPY IN INFLAMMATORY BOWEL DISEASE
WO2010075579A2 (en) * 2008-12-24 2010-07-01 Cedars-Sinai Medical Center Methods of predicting medically refractive ulcerative colitis (mr-uc) requiring colectomy
EP2406396A2 (en) 2009-03-12 2012-01-18 Brainco Biopharma, S.L. A genotyping tool for improving the prognostic and clinical management of ms patients
WO2011027218A1 (en) * 2009-09-04 2011-03-10 Progenika Biopharma, S.A. High throughput detection of genomic copy number variations
US9677125B2 (en) * 2009-10-21 2017-06-13 General Electric Company Detection of plurality of targets in biological samples
US9558320B2 (en) * 2009-10-26 2017-01-31 Genomas, Inc. Physiogenomic method for predicting drug metabolism reserve for antidepressants and stimulants
US20130085081A1 (en) * 2010-06-08 2013-04-04 National Cancer Center Risk prediction of developing drug-induced lung injury and detection method and kit of gene for risk prediction
EP2397561B1 (en) 2010-06-18 2017-08-02 Progenika Biopharma, S.A. Methods for determining the presence or absence of genetic segments
US8766034B2 (en) 2010-09-22 2014-07-01 Cedars-Sinai Medical Center TL1A model of inflammation fibrosis and autoimmunity
ES2445709T3 (es) * 2010-12-31 2014-03-04 Progenika Biopharma, S.A. Método para la identificación por técnicas moleculares de variantes genéticas que no codifican antígeno D (D-) y codifican antígeno C alterado (C+W)
EP2497835B1 (en) * 2011-03-09 2015-08-12 ARKRAY, Inc. Probe for detecting polymorphism in CYP3A gene, method of detecting polymorphism, method of evaluating drug efficacy, and reagent kit for detecting polymorphism
EP2535424B1 (en) * 2011-06-16 2015-08-05 Gendiag.exe, S.L. SNPs associated with thromboemoblic disease
US10557170B2 (en) 2011-06-16 2020-02-11 Gendiag.Exe, S.L. Thromboembolic disease markers
WO2012171990A1 (en) * 2011-06-17 2012-12-20 Progenika Biopharma, S.A. Discrimination of blood type variants
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WO2013107005A1 (zh) * 2012-01-18 2013-07-25 上海市血液中心 人稀有血型的多重pcr检测方法和试剂盒
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US20140274763A1 (en) * 2013-03-15 2014-09-18 Pathway Genomics Corporation Method and system to predict response to pain treatments
KR20230109779A (ko) 2013-03-27 2023-07-20 세다르스-신나이 메디칼 센터 Tl1a 기능 및 관련된 신호전달 경로의 저해에 의한섬유증 및 염증의 완화 및 반전
EP4105236A1 (en) 2013-07-19 2022-12-21 Cedars-Sinai Medical Center Anti-tl1a (tnfsf15) antibody for treatment of inflammatory bowel disease
JP2015128399A (ja) * 2014-01-09 2015-07-16 東洋紡株式会社 Cyp3a5の検出方法
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US11699069B2 (en) * 2017-07-13 2023-07-11 Helix, Inc. Predictive assignments that relate to genetic information and leverage machine learning models
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WO2019075577A1 (en) 2017-10-20 2019-04-25 The Governors Of The University Of Alberta Mononucleotide Polymorphisms and Feed Efficacy in Livestock
JP6995604B2 (ja) * 2017-12-15 2022-01-14 東洋鋼鈑株式会社 一塩基多型検出用プローブの設計方法及びプローブセット
CN112602153A (zh) * 2018-08-30 2021-04-02 生命科技股份有限公司 用于对pcr测定进行基因分型的机器学习系统
WO2021162028A1 (ja) * 2020-02-14 2021-08-19 東レ株式会社 バイオチップの製造方法
CN112442532B (zh) * 2020-08-27 2023-09-26 深圳市卫生健康发展研究中心 同时检测20种葡萄糖-6-磷酸脱氢酶缺乏症的引物组及试剂盒

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Also Published As

Publication number Publication date
EP1836322B8 (en) 2017-01-11
EP1836322B1 (en) 2016-09-07
WO2006075254A3 (en) 2007-03-22
AU2006205571B2 (en) 2012-03-22
EP1836322A2 (en) 2007-09-26
AU2006205571A1 (en) 2006-07-20
JP2008526249A (ja) 2008-07-24
WO2006075254A2 (en) 2006-07-20
MX2007008506A (es) 2010-05-17
US20080070253A1 (en) 2008-03-20
US7914990B2 (en) 2011-03-29

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Effective date: 20170330