CA2578736C - Strain of lactobacillus acidophilus having analgesic properties in the gastrointestinal system - Google Patents
Strain of lactobacillus acidophilus having analgesic properties in the gastrointestinal system Download PDFInfo
- Publication number
- CA2578736C CA2578736C CA2578736A CA2578736A CA2578736C CA 2578736 C CA2578736 C CA 2578736C CA 2578736 A CA2578736 A CA 2578736A CA 2578736 A CA2578736 A CA 2578736A CA 2578736 C CA2578736 C CA 2578736C
- Authority
- CA
- Canada
- Prior art keywords
- lactobacillus acidophilus
- strain
- gastrointestinal system
- receptors
- humans
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 240000001046 Lactobacillus acidophilus Species 0.000 title claims abstract description 16
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 title claims abstract description 16
- 229940039695 lactobacillus acidophilus Drugs 0.000 title claims abstract description 16
- 230000000202 analgesic effect Effects 0.000 title claims abstract description 10
- 210000005095 gastrointestinal system Anatomy 0.000 title claims abstract description 10
- 241001465754 Metazoa Species 0.000 claims abstract 8
- 210000002919 epithelial cell Anatomy 0.000 claims 4
- 238000000034 method Methods 0.000 claims 4
- 102100036214 Cannabinoid receptor 2 Human genes 0.000 claims 3
- 244000116699 Lactobacillus acidophilus NCFM Species 0.000 claims 3
- 235000009195 Lactobacillus acidophilus NCFM Nutrition 0.000 claims 3
- 102000003840 Opioid Receptors Human genes 0.000 claims 3
- 108090000137 Opioid Receptors Proteins 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 238000000338 in vitro Methods 0.000 claims 3
- 238000004519 manufacturing process Methods 0.000 claims 3
- 244000005700 microbiome Species 0.000 claims 3
- 241000894006 Bacteria Species 0.000 claims 2
- 102000009132 CB1 Cannabinoid Receptor Human genes 0.000 claims 2
- 108010073366 CB1 Cannabinoid Receptor Proteins 0.000 claims 2
- 102000009135 CB2 Cannabinoid Receptor Human genes 0.000 claims 2
- 108010073376 CB2 Cannabinoid Receptor Proteins 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 230000036592 analgesia Effects 0.000 claims 2
- 229930003827 cannabinoid Natural products 0.000 claims 2
- 239000003557 cannabinoid Substances 0.000 claims 2
- 210000004027 cell Anatomy 0.000 claims 2
- 230000001404 mediated effect Effects 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 102000018208 Cannabinoid Receptor Human genes 0.000 claims 1
- 108050007331 Cannabinoid receptor Proteins 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
- 102000005962 receptors Human genes 0.000 claims 1
- 108020003175 receptors Proteins 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 description 16
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/12—Fermented milk preparations; Treatment using microorganisms or enzymes
- A23C9/123—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt
- A23C9/1234—Fermented milk preparations; Treatment using microorganisms or enzymes using only microorganisms of the genus lactobacteriaceae; Yoghurt characterised by using a Lactobacillus sp. other than Lactobacillus Bulgaricus, including Bificlobacterium sp.
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/152—Milk preparations; Milk powder or milk powder preparations containing additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
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- A61K35/745—Bifidobacteria
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
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- G—PHYSICS
- G01—MEASURING; TESTING
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/948—Sedatives, e.g. cannabinoids, barbiturates
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
- G01N33/9486—Analgesics, e.g. opiates, aspirine
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/113—Acidophilus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K2035/11—Medicinal preparations comprising living procariotic cells
- A61K2035/115—Probiotics
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
- C12R2001/23—Lactobacillus acidophilus
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
- G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Mycology (AREA)
- Immunology (AREA)
- Food Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Polymers & Plastics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Epidemiology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nutrition Science (AREA)
- Genetics & Genomics (AREA)
- Pain & Pain Management (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Engineering & Computer Science (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0409966A FR2875406B1 (fr) | 2004-09-21 | 2004-09-21 | Souche de lactobacillus acidophilus ayant des proprietes analgesiques au niveau du systeme gastro-intestinal |
FR0409966 | 2004-09-21 | ||
PCT/EP2005/010880 WO2006032542A1 (en) | 2004-09-21 | 2005-09-21 | Strain of lactobacillus acidophilus having analgesic properties in the gastrointestinal system |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2578736A1 CA2578736A1 (en) | 2006-03-30 |
CA2578736C true CA2578736C (en) | 2016-08-23 |
Family
ID=34948825
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2578736A Expired - Fee Related CA2578736C (en) | 2004-09-21 | 2005-09-21 | Strain of lactobacillus acidophilus having analgesic properties in the gastrointestinal system |
Country Status (15)
Country | Link |
---|---|
US (4) | US20070298080A1 (pl) |
EP (1) | EP1796698B1 (pl) |
JP (2) | JP5162243B2 (pl) |
KR (1) | KR20070054670A (pl) |
CN (3) | CN101094682A (pl) |
AT (1) | ATE531379T1 (pl) |
AU (1) | AU2005287482B2 (pl) |
CA (1) | CA2578736C (pl) |
DK (1) | DK1796698T3 (pl) |
ES (1) | ES2376864T3 (pl) |
FR (1) | FR2875406B1 (pl) |
NZ (1) | NZ553616A (pl) |
PL (1) | PL1796698T3 (pl) |
PT (1) | PT1796698E (pl) |
WO (1) | WO2006032542A1 (pl) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2875406B1 (fr) * | 2004-09-21 | 2007-01-05 | Danisco | Souche de lactobacillus acidophilus ayant des proprietes analgesiques au niveau du systeme gastro-intestinal |
WO2007132359A2 (en) * | 2006-05-12 | 2007-11-22 | Danisco A/S | Composition containing lactobacillus sp. and a cannabinoid receptor and/or a opioid receptor agonist |
US9055763B2 (en) * | 2007-10-11 | 2015-06-16 | Dupont Nutrition Biosciences Aps | Probiotics for use in relieving symptoms associated with gastronitestinal disorders |
JP6077303B2 (ja) | 2009-05-07 | 2017-02-08 | タト エ リル アングルディアント フランス ソシエテ パ アクシオンス シンプリフィエ | アルファ−(1,2)−分岐アルファ−(1,6)オリゴデキストランを含有する組成物及びアルファ−(1,2)−分岐アルファ−(1,6)オリゴデキストランの製造方法 |
US8445226B2 (en) | 2010-02-01 | 2013-05-21 | Microbios, Inc. | Process and composition for the manufacture of a microbial-based product |
US7888062B1 (en) | 2010-02-01 | 2011-02-15 | Microbios, Inc. | Process and composition for the manufacture of a microbial-based product |
WO2011148219A1 (en) | 2010-05-28 | 2011-12-01 | Compagnie Gervais Danone | Probiotic strains for use in improving the enteric nervous system |
RU2642306C2 (ru) | 2012-05-21 | 2018-01-24 | ДюПон НЬЮТРИШН БАЙОСАЙЕНСИЗ АпС | Штамм lactobacillus, обладающий ингибирующей активностью против дрожжей и плесневых грибов (варианты), и его применение |
RU2640255C2 (ru) | 2012-05-21 | 2017-12-27 | ДюПон НЬЮТРИШН БАЙОСАЙЕНСИЗ АпС | Штамм propionibacterium, обладающий ингибирующей активностью против дрожжей и плесневых грибов (варианты) и его применение |
US9730969B2 (en) | 2015-11-06 | 2017-08-15 | Mead Johnson Nutrition Company | Nutritional compositions for promoting gut barrier function and ameliorating visceral pain |
CN108102960B (zh) * | 2017-12-25 | 2020-12-25 | 齐鲁工业大学 | 一种嗜酸乳杆菌ncfm耐酸保护剂 |
CN108949643A (zh) * | 2018-08-31 | 2018-12-07 | 重庆子和杉农业发展有限公司 | 一种培育兔用乳酸菌的方法和无公害养兔的方法 |
WO2021156777A1 (en) * | 2020-02-06 | 2021-08-12 | Buzzelet Development And Technologies Ltd. | Microbial combinations and uses thereof |
WO2021161205A1 (en) * | 2020-02-13 | 2021-08-19 | Eyal Research Consultants Ltd | Microbial combinations with modulators of the opioid system and uses thereof |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4839281A (en) * | 1985-04-17 | 1989-06-13 | New England Medical Center Hospitals, Inc. | Lactobacillus strains and methods of selection |
US5858356A (en) * | 1995-12-21 | 1999-01-12 | Abbott Laboratories | Lactobacillus acidophilus to inhibit cryptosporidiosis in mammals |
JPH11504048A (ja) * | 1996-02-14 | 1999-04-06 | ザ、プロクター、エンド、ギャンブル、カンパニー | 泌尿生殖器および腸用の組成物 |
US6203797B1 (en) * | 1998-01-06 | 2001-03-20 | Stephen C. Perry | Dietary supplement and method for use as a probiotic, for alleviating the symptons associated with irritable bowel syndrome |
CH693625A5 (it) * | 1999-02-18 | 2003-11-28 | Inpharma Sa | Composizioni farmaceutiche contenenti composti ad attività promotrice di assorbimento di principi attivi. |
KR100357668B1 (ko) * | 2000-02-19 | 2002-10-18 | 주식회사 한국야쿠르트 | 헬리코박터 필로리에 대해 항균활성을 갖는 락토바실러스애시도필러스 에이치 와이 2177, 락토바실러스 카제이에이치 와이2743 및 그를 이용한 유산균 제제, 발효유 |
US7125884B2 (en) * | 2001-03-02 | 2006-10-24 | Euro-Celtique S.A. | N-but-3-enyl norbuprenorphine and its use as analgesic |
AU2002329043A1 (en) * | 2001-07-30 | 2003-02-24 | Claudio De Simone | Treatment of radiation-induced diarrhea with probiotics |
US20040005304A1 (en) * | 2002-07-08 | 2004-01-08 | Mak Wood, Inc. | Novel compositions and methods for treating neurological disorders and associated gastrointestinal conditions |
US7179460B2 (en) * | 2002-12-05 | 2007-02-20 | Danisco A/S | Bacterial composition and its use |
EP2287616A1 (en) * | 2003-09-15 | 2011-02-23 | Oklahoma Medical Research Foundation | Method of using cytokine assays to diagnose, treat, and evaluate systemic lupus erythematosus |
FR2875406B1 (fr) * | 2004-09-21 | 2007-01-05 | Danisco | Souche de lactobacillus acidophilus ayant des proprietes analgesiques au niveau du systeme gastro-intestinal |
-
2004
- 2004-09-21 FR FR0409966A patent/FR2875406B1/fr not_active Expired - Fee Related
-
2005
- 2005-09-21 US US11/661,534 patent/US20070298080A1/en not_active Abandoned
- 2005-09-21 DK DK05788495.9T patent/DK1796698T3/da active
- 2005-09-21 AU AU2005287482A patent/AU2005287482B2/en not_active Ceased
- 2005-09-21 AT AT05788495T patent/ATE531379T1/de active
- 2005-09-21 CA CA2578736A patent/CA2578736C/en not_active Expired - Fee Related
- 2005-09-21 CN CNA2005800315405A patent/CN101094682A/zh active Pending
- 2005-09-21 KR KR1020077006484A patent/KR20070054670A/ko not_active Application Discontinuation
- 2005-09-21 WO PCT/EP2005/010880 patent/WO2006032542A1/en active Application Filing
- 2005-09-21 ES ES05788495T patent/ES2376864T3/es active Active
- 2005-09-21 CN CN201410119530.8A patent/CN103961377A/zh active Pending
- 2005-09-21 NZ NZ553616A patent/NZ553616A/en unknown
- 2005-09-21 PL PL05788495T patent/PL1796698T3/pl unknown
- 2005-09-21 PT PT05788495T patent/PT1796698E/pt unknown
- 2005-09-21 CN CN201711364330.9A patent/CN107982283B/zh active Active
- 2005-09-21 EP EP05788495A patent/EP1796698B1/en active Active
- 2005-09-21 JP JP2007531724A patent/JP5162243B2/ja not_active Expired - Fee Related
-
2012
- 2012-08-03 JP JP2012172823A patent/JP2012246300A/ja active Pending
-
2014
- 2014-10-03 US US14/506,065 patent/US20150023936A1/en not_active Abandoned
-
2017
- 2017-06-15 US US15/624,083 patent/US20180036355A1/en not_active Abandoned
-
2020
- 2020-02-24 US US16/798,913 patent/US20200323930A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20150023936A1 (en) | 2015-01-22 |
ES2376864T3 (es) | 2012-03-20 |
US20070298080A1 (en) | 2007-12-27 |
AU2005287482A1 (en) | 2006-03-30 |
FR2875406A1 (fr) | 2006-03-24 |
PT1796698E (pt) | 2012-02-07 |
CN103961377A (zh) | 2014-08-06 |
EP1796698B1 (en) | 2011-11-02 |
CN107982283A (zh) | 2018-05-04 |
DK1796698T3 (da) | 2012-02-27 |
FR2875406B1 (fr) | 2007-01-05 |
CA2578736A1 (en) | 2006-03-30 |
JP2012246300A (ja) | 2012-12-13 |
ATE531379T1 (de) | 2011-11-15 |
JP2008513411A (ja) | 2008-05-01 |
KR20070054670A (ko) | 2007-05-29 |
JP5162243B2 (ja) | 2013-03-13 |
CN107982283B (zh) | 2021-09-28 |
PL1796698T3 (pl) | 2012-05-31 |
EP1796698A1 (en) | 2007-06-20 |
US20200323930A1 (en) | 2020-10-15 |
US20180036355A1 (en) | 2018-02-08 |
NZ553616A (en) | 2010-05-28 |
AU2005287482B2 (en) | 2011-08-25 |
CN101094682A (zh) | 2007-12-26 |
WO2006032542A1 (en) | 2006-03-30 |
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