CA2575787C - Dihydropteridinones for the treatment of cancer diseases - Google Patents
Dihydropteridinones for the treatment of cancer diseases Download PDFInfo
- Publication number
- CA2575787C CA2575787C CA2575787A CA2575787A CA2575787C CA 2575787 C CA2575787 C CA 2575787C CA 2575787 A CA2575787 A CA 2575787A CA 2575787 A CA2575787 A CA 2575787A CA 2575787 C CA2575787 C CA 2575787C
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- Prior art keywords
- mixture
- compound
- alkyl
- polymorph
- racemate
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- Biomedical Technology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Dermatology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Communicable Diseases (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04019359.1 | 2004-08-14 | ||
| EP04019359 | 2004-08-14 | ||
| PCT/EP2005/008626 WO2006018185A2 (en) | 2004-08-14 | 2005-08-09 | Dihydropteridinones for the treatment of cancer diseases |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2575787A1 CA2575787A1 (en) | 2006-02-23 |
| CA2575787C true CA2575787C (en) | 2013-12-24 |
Family
ID=34926179
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2575787A Expired - Fee Related CA2575787C (en) | 2004-08-14 | 2005-08-09 | Dihydropteridinones for the treatment of cancer diseases |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US20060074088A1 (https=) |
| EP (3) | EP1778240B1 (https=) |
| JP (2) | JP2008509949A (https=) |
| KR (2) | KR101283378B1 (https=) |
| CN (2) | CN104055778A (https=) |
| AR (1) | AR050694A1 (https=) |
| AU (1) | AU2005274387B2 (https=) |
| BR (1) | BRPI0513977A (https=) |
| CA (1) | CA2575787C (https=) |
| ES (2) | ES2800308T3 (https=) |
| IL (2) | IL181304A (https=) |
| MX (2) | MX2007001851A (https=) |
| NZ (1) | NZ553722A (https=) |
| PL (1) | PL3560499T3 (https=) |
| RU (1) | RU2406503C2 (https=) |
| TW (1) | TWI360420B (https=) |
| WO (1) | WO2006018185A2 (https=) |
| ZA (1) | ZA200700281B (https=) |
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| DE102004033670A1 (de) * | 2004-07-09 | 2006-02-02 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue Pyridodihydropyrazinone, Verfahren zu Ihrer Herstellung und Ihre Verwendung als Arzneimittel |
| US20060074088A1 (en) * | 2004-08-14 | 2006-04-06 | Boehringer Ingelheim International Gmbh | Dihydropteridinones for the treatment of cancer diseases |
| US7728134B2 (en) * | 2004-08-14 | 2010-06-01 | Boehringer Ingelheim International Gmbh | Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament |
| US20060058311A1 (en) | 2004-08-14 | 2006-03-16 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation |
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| US7759485B2 (en) * | 2004-08-14 | 2010-07-20 | Boehringer Ingelheim International Gmbh | Process for the manufacture of dihydropteridinones |
| EP1630163A1 (de) * | 2004-08-25 | 2006-03-01 | Boehringer Ingelheim Pharma GmbH & Co.KG | Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| EP1632493A1 (de) * | 2004-08-25 | 2006-03-08 | Boehringer Ingelheim Pharma GmbH & Co.KG | Dihydropteridinonderivative, Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
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| EP2536725B1 (en) | 2010-02-17 | 2015-10-28 | Boehringer Ingelheim International GmbH | Dihydropteridinones, method for production and use thereof |
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| MX354217B (es) | 2010-05-14 | 2018-02-19 | Dana Farber Cancer Inst Inc | Composiciones y metodos para el tratamiento de leucemia. |
| CN103180318B (zh) | 2010-05-14 | 2017-05-10 | 达那-法伯癌症研究所 | 雄性避孕组合物以及使用方法 |
| AU2011261375B2 (en) | 2010-06-04 | 2016-09-22 | Albany Molecular Research, Inc. | Glycine transporter-1 inhibitors, methods of making them, and uses thereof |
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| US9358233B2 (en) | 2010-11-29 | 2016-06-07 | Boehringer Ingelheim International Gmbh | Method for treating acute myeloid leukemia |
| CA2827770A1 (en) | 2011-02-25 | 2012-11-01 | Takeda Pharmaceutical Company Limited | N-substituted oxazinopteridines and oxazinopteridinones |
| US20130131069A1 (en) * | 2011-05-13 | 2013-05-23 | Boehringer Ingelheim International Gmbh | Method for treatment of solid malignancies including advanced or metastatic solid malignancies |
| US9370535B2 (en) | 2011-05-17 | 2016-06-21 | Boehringer Ingelheim International Gmbh | Method for treatment of advanced solid tumors |
| US9714946B2 (en) | 2013-03-14 | 2017-07-25 | Dana-Farber Cancer Institute, Inc. | Bromodomain binding reagents and uses thereof |
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| BR112016017045A2 (pt) | 2014-01-31 | 2017-08-08 | Dana Farber Cancer Inst Inc | Derivados de diazepano e usos dos mesmos |
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-
2005
- 2005-07-25 US US11/188,926 patent/US20060074088A1/en not_active Abandoned
- 2005-08-09 BR BRPI0513977-5A patent/BRPI0513977A/pt not_active IP Right Cessation
- 2005-08-09 CA CA2575787A patent/CA2575787C/en not_active Expired - Fee Related
- 2005-08-09 KR KR1020077005855A patent/KR101283378B1/ko not_active Expired - Fee Related
- 2005-08-09 CN CN201410065809.2A patent/CN104055778A/zh active Pending
- 2005-08-09 KR KR1020137009370A patent/KR101353990B1/ko not_active Expired - Fee Related
- 2005-08-09 ES ES05770942T patent/ES2800308T3/es not_active Expired - Lifetime
- 2005-08-09 NZ NZ553722A patent/NZ553722A/en not_active IP Right Cessation
- 2005-08-09 PL PL19168693.0T patent/PL3560499T3/pl unknown
- 2005-08-09 ES ES19168693T patent/ES2975234T3/es not_active Expired - Lifetime
- 2005-08-09 JP JP2007526350A patent/JP2008509949A/ja not_active Withdrawn
- 2005-08-09 CN CNA2005800277121A patent/CN101022809A/zh active Pending
- 2005-08-09 EP EP05770942.0A patent/EP1778240B1/en not_active Expired - Lifetime
- 2005-08-09 EP EP19168693.0A patent/EP3560499B1/en not_active Expired - Lifetime
- 2005-08-09 EP EP11185693A patent/EP2409706A1/en not_active Withdrawn
- 2005-08-09 MX MX2007001851A patent/MX2007001851A/es active IP Right Grant
- 2005-08-09 RU RU2007109109/15A patent/RU2406503C2/ru not_active IP Right Cessation
- 2005-08-09 MX MX2012004012A patent/MX343697B/es unknown
- 2005-08-09 WO PCT/EP2005/008626 patent/WO2006018185A2/en not_active Ceased
- 2005-08-09 AU AU2005274387A patent/AU2005274387B2/en not_active Ceased
- 2005-08-12 TW TW094127427A patent/TWI360420B/zh not_active IP Right Cessation
- 2005-08-12 AR ARP050103378A patent/AR050694A1/es unknown
-
2007
- 2007-01-10 ZA ZA200700281A patent/ZA200700281B/xx unknown
- 2007-02-13 IL IL181304A patent/IL181304A/en not_active IP Right Cessation
-
2008
- 2008-05-15 US US12/120,740 patent/US8058270B2/en active Active
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2012
- 2012-07-05 JP JP2012151593A patent/JP2012211178A/ja active Pending
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2013
- 2013-08-07 IL IL227841A patent/IL227841A/en not_active IP Right Cessation
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